Mitogen-activated protein kinase p38 and retinoblastoma protein signalling is required for DNA damage-mediated formation of senescence-associated heterochromatic foci in tumour cells

Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16ink4a

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Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

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miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1

(2010) Hongling Li et al.   BREAST CANCER RESEARCH AND TREATMENT

Changed Genome Heterochromatinization Upon Prolonged Activation of the Raf/ERK Signaling Pathway

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Stress-Activated MAP Kinase Cascades in Cellular Senescence

(2009) Junichi Maruyama et al.   CURRENT MEDICINAL CHEMISTRY

BMP4-Smad Signaling Pathway Mediates Adriamycin-induced Premature Senescence in Lung Cancer Cells

(2009) Dongmei Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

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