Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme

The predicated demise of racemic new molecular entities is an exaggeration

(2012) Israel Agranat et al.   NATURE REVIEWS DRUG DISCOVERY

Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides

(2012) Geoffrey Masuyer et al.   Scientific Reports

Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide

(2011) Mohd Akif et al.   BIOCHEMICAL JOURNAL

Characterization of domain-selective inhibitor binding in angiotensin-converting enzyme using a novel derivative of lisinopril

(2010) Jean M. Watermeyer et al.   BIOCHEMICAL JOURNAL

The N Domain of Human Angiotensin-I-converting Enzyme

(2010) Colin S. Anthony et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-Resolution Crystal Structures of Drosophila melanogaster Angiotensin-Converting Enzyme in Complex with Novel Inhibitors and Antihypertensive Drugs

(2010) Mohd Akif et al.   JOURNAL OF MOLECULAR BIOLOGY

Inhibition of Zinc Metallopeptidases in Cardiovascular Disease - From Unity to Trinity, or Duality?

(2009) Vincent Dive et al.   CURRENT PHARMACEUTICAL DESIGN

Phosphinic Tripeptides as Dual Angiotensin-Converting Enzyme C-Domain and Endothelin-Converting Enzyme-1 Inhibitors

(2009) Nicolas Jullien et al.   JOURNAL OF MEDICINAL CHEMISTRY

Probing the Basis of Domain-Dependent Inhibition Using Novel Ketone Inhibitors of Angiotensin-Converting Enzyme†‡

(2008) Jean M. Watermeyer et al.   BIOCHEMISTRY

Structure of human Endothelin-converting Enzyme I Complexed with Phosphoramidon

(2008) Henk Schulz et al.   JOURNAL OF MOLECULAR BIOLOGY