Ryanodine receptor calcium release channels: lessons from structure-function studies

An α-helical C-terminal tail segment of the skeletal L-type Ca2+ channel β1a subunit activates ryanodine receptor type 1 via a hydrophobic surface

(2012) Yamuna Karunasekara et al.   FASEB JOURNAL

Structural determination of the phosphorylation domain of the ryanodine receptor

(2012) Parveen Sharma et al.   FEBS Journal

Calmodulin-binding Locations on the Skeletal and Cardiac Ryanodine Receptors

(2012) Xiaojun Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ryanodine Receptors: Structure and Function

(2012) Filip Van Petegem   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and functional conservation of key domains in InsP3 and ryanodine receptors

(2012) Min-Duk Seo et al.   NATURE

FRET-Based Localization of Fluorescent Protein Insertions Within the Ryanodine Receptor Type 1

(2012) Shweta A. Raina et al.   PLoS One

Disease Mutations in the Ryanodine Receptor Central Region: Crystal Structures of a Phosphorylation Hot Spot Domain

(2012) Zhiguang Yuchi et al.   STRUCTURE

Mapping domains and mutations on the skeletal muscle ryanodine receptor channel

(2012) Jean H. Hwang et al.   TRENDS IN MOLECULAR MEDICINE

Complications Associated with the Administration of Dantrolene 1987 to 2006

(2011) Barbara W. Brandom et al.   ANESTHESIA AND ANALGESIA

Functional characterization of the P1059L mutation in the inositol 1,4,5-trisphosphate receptor type 1 identified in a Japanese SCA15 family

(2011) Haruka Yamazaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The β1a Subunit of the Skeletal DHPR Binds to Skeletal RyR1 and Activates the Channel via Its 35-Residue C-Terminal Tail

(2011) Robyn T. Rebbeck et al.   BIOPHYSICAL JOURNAL

S100A1 and calmodulin regulation of ryanodine receptor in striated muscle

(2011) Benjamin L. Prosser et al.   CELL CALCIUM

Common allosteric mechanisms between ryanodine and inositol-1,4,5-trisphosphate receptors

(2011) Zhiguang Yuchi et al.   Channels

Mutation-Linked Defective Interdomain Interactions Within Ryanodine Receptor Cause Aberrant Ca 2+ Release Leading to Catecholaminergic Polymorphic Ventricular Tachycardia

(2011) Takeshi Suetomi et al.   CIRCULATION

Cyclization of the Intrinsically Disordered α1SDihydropyridine Receptor II-III Loop Enhances Secondary Structure andin VitroFunction

(2011) Han-Shen Tae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ancestral Ca2+ Signaling Machinery in Early Animal and Fungal Evolution

(2011) X. Cai et al.   MOLECULAR BIOLOGY AND EVOLUTION

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Apo and InsP3-bound crystal structures of the ligand-binding domain of an InsP3 receptor

(2011) Chun-Chi Lin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease

(2011) Angela M. Bruno et al.   NEUROBIOLOGY OF AGING

Identification of Intracellular and Plasma Membrane Calcium Channel Homologues in Pathogenic Parasites

(2011) David L. Prole et al.   PLoS One

The structural biology of ryanodine receptors

(2011) Lynn Kimlicka et al.   Science China-Life Sciences

Flexible Architecture of IP3R1 by Cryo-EM

(2011) Steven J. Ludtke et al.   STRUCTURE

The Deletion of Exon 3 in the Cardiac Ryanodine Receptor Is Rescued by β Strand Switching

(2011) Paolo A. Lobo et al.   STRUCTURE

Kinetics of FKBP12.6 Binding to Ryanodine Receptors in Permeabilized Cardiac Myocytes and Effects on Ca Sparks

(2010) Tao Guo et al.   CIRCULATION RESEARCH

Looking for answers to EC coupling’s persistent questions: Figure 1.

(2010) Kurt G. Beam et al.   JOURNAL OF GENERAL PHYSIOLOGY

The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule

(2010) Ching-Chieh Tung et al.   NATURE

Calcium Signalling and Alzheimer’s Disease

(2010) Michael J. Berridge   NEUROCHEMICAL RESEARCH

Ryanodine Receptors: Structure, Expression, Molecular Details, and Function in Calcium Release

(2010) J. T. Lanner et al.   Cold Spring Harbor Perspectives in Biology

The Relationship Between Exertional Heat Illness, Exertional Rhabdomyolysis, and Malignant Hyperthermia

(2009) John F. Capacchione et al.   ANESTHESIA AND ANALGESIA

The voltage-gated calcium-channel β subunit: more than just an accessory

(2009) Yamuna Karunasekara et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Ubiquitous SPRY domains and their role in the skeletal type ryanodine receptor

(2009) HanShen Tae et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Crystal structure of type I ryanodine receptor amino-terminal  -trefoil domain reveals a disease-associated mutation "hot spot" loop

(2009) F. J. Amador et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structures of the N-Terminal Domains of Cardiac and Skeletal Muscle Ryanodine Receptors: Insights into Disease Mutations

(2009) Paolo Antonio Lobo et al.   STRUCTURE

Comprehensive behavioral phenotyping of ryanodine receptor type3 (RyR3) knockout mice: Decreased social contact duration in two social interaction tests

(2009) Naoki Matsuo   Frontiers in Behavioral Neuroscience

Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating

(2009) Montserrat Samsó et al.   PLOS BIOLOGY

Trends and Outcomes of Malignant Hyperthermia in the United States, 2000 to 2005

(2008) Eric B. Rosero et al.   ANESTHESIOLOGY

Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts

(2008) H. Tateishi et al.   CARDIOVASCULAR RESEARCH

RyR1 S-Nitrosylation Underlies Environmental Heat Stroke and Sudden Death in Y522S RyR1 Knockin Mice

(2008) William J. Durham et al.   CELL

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors

(2008) Nanaho Fukuda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A dihydropyridine receptor α1s loop region critical for skeletal muscle contraction is intrinsically unstructured and binds to a SPRY domain of the type 1 ryanodine receptor

(2008) Yanfang Cui et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

S100A1 and Calmodulin Compete for the Same Binding Site on Ryanodine Receptor

(2008) Nathan T. Wright et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unicellular Ca2+ Signaling 'Toolkit' at the Origin of Metazoa

(2008) X. Cai   MOLECULAR BIOLOGY AND EVOLUTION

Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel

(2008) I. I. Serysheva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ryanodine receptor arrays: not just a pretty pattern?

(2008) Chang-Cheng Yin et al.   TRENDS IN CELL BIOLOGY