Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi

Rescuing Mutant CFTR: A Multi-task Approach to a Better Outcome in Treating Cystic Fibrosis

(2013) Margarida D. Amaral et al.   CURRENT PHARMACEUTICAL DESIGN

HGF Stimulation of Rac1 Signaling Enhances Pharmacological Correction of the Most Prevalent Cystic Fibrosis Mutant F508del-CFTR

(2012) Sónia Moniz et al.   ACS Chemical Biology

GTPase Networks in Membrane Traffic

(2012) Emi Mizuno-Yamasaki et al.   Annual Review of Biochemistry

Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator

(2012) Alessandro Luciani et al.   Autophagy

Improvement of defective cystic fibrosis airway epithelial wound repair after CFTR rescue

(2012) Nguyen Thu Ngan Trinh et al.   EUROPEAN RESPIRATORY JOURNAL

The Ras protein superfamily: Evolutionary tree and role of conserved amino acids

(2012) Ana Maria Rojas et al.   JOURNAL OF CELL BIOLOGY

NHERF1 and CFTR restore tight junction organisation and function in cystic fibrosis airway epithelial cells: role of ezrin and the RhoA/ROCK pathway

(2012) Stefano Castellani et al.   LABORATORY INVESTIGATION

A Chaperone Trap Contributes to the Onset of Cystic Fibrosis

(2012) Judith A. Coppinger et al.   PLoS One

Autophagy stimulation by rapamycin suppresses lung inflammation and infection byBurkholderia cenocepaciain a model of cystic fibrosis

(2011) Basant A. Abdulrahman et al.   Autophagy

Rescue of ΔF508-CFTR Trafficking via a GRASP-Dependent Unconventional Secretion Pathway

(2011) Heon Yung Gee et al.   CELL

Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect

(2011) Julien Colas et al.   HUMAN MOLECULAR GENETICS

C-Terminus Glycans with Critical Functional Role in the Maturation of Secretory Glycoproteins

(2011) Daniela Cioaca et al.   PLoS One

The Cystic Fibrosis-causing Mutation ΔF508 Affects Multiple Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis

(2010) Patrick H. Thibodeau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Annexin A5 on CFTR: regulated traffic or scaffolding?

(2010) Diana Faria et al.   MOLECULAR MEMBRANE BIOLOGY

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

(2010) Alessandro Luciani et al.   NATURE CELL BIOLOGY

Peripheral Protein Quality Control Removes Unfolded CFTR from the Plasma Membrane

(2010) T. Okiyoneda et al.   SCIENCE

Multifaceted role of Rho, Rac, Cdc42 and Ras in intercellular junctions, lessons from toxins

(2009) Michel R. Popoff et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Deletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperone

(2009) Toby S. Scott-Ward et al.   FEBS Journal

Rab11b Regulates the Apical Recycling of the Cystic Fibrosis Transmembrane Conductance Regulator in Polarized Intestinal Epithelial Cells

(2009) Mark R. Silvis et al.   MOLECULAR BIOLOGY OF THE CELL

Na+/H+ Exchanger Regulatory Factor 1 Overexpression-dependent Increase of Cytoskeleton Organization Is Fundamental in the Rescue of F508del Cystic Fibrosis Transmembrane Conductance Regulator in Human Airway CFBE41o- Cells

(2009) Maria Favia et al.   MOLECULAR BIOLOGY OF THE CELL

Rab GTPase function in Golgi trafficking

(2009) Francis A. Barr   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Remodeling Epithelial Cell Organization: Transitions Between Front-Rear and Apical-Basal Polarity

(2009) W. J. Nelson   Cold Spring Harbor Perspectives in Biology

Actin Binding of Ezrin Is Activated by Specific Recognition of PIP2-Functionalized Lipid Bilayers†

(2008) Matthias Janke et al.   BIOCHEMISTRY

Membrane traffic in the secretory pathway

(2008) M. Fukuda   CELLULAR AND MOLECULAR LIFE SCIENCES

Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

(2008) A. W. R. Serohijos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA