Relating localized protein motions to the reaction coordinate in coenzyme B12-dependent enzymes

Mutagenesis of a Conserved Glutamate Reveals the Contribution of Electrostatic Energy to Adenosylcobalamin Co–C Bond Homolysis in Ornithine 4,5-Aminomutase and Methylmalonyl-CoA Mutase

(2013) Caitlyn Makins et al.   BIOCHEMISTRY

Fast Protein Motions Are Coupled to Enzyme H-Transfer Reactions

(2013) Christopher R. Pudney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogen Bonds Guide the Short-Lived 5′-Deoxyadenosyl Radical to the Place of Action

(2012) Wolfgang Buckel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Motions Are Coupled to the Reaction Chemistry in Coenzyme B12-Dependent Ethanolamine Ammonia Lyase

(2012) Henry J. Russell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical Use of Rossmann and TIM Barrel Architectures for Controlling Coenzyme B12 Chemistry

(2012) Daniel P. Dowling et al.   Annual Review of Biophysics

Adenosylcobalamin enzymes: Theory and experiment begin to converge

(2012) E. Neil G. Marsh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Ultrafast Infrared Spectral Fingerprints of Vitamin B12 and Related Cobalamins

(2012) Alex R. Jones et al.   JOURNAL OF PHYSICAL CHEMISTRY A

The Elusive 5′-Deoxyadenosyl Radical in Coenzyme-B12-Mediated Reactions

(2012) Denis Bucher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

B12 cofactors directly stabilize an mRNA regulatory switch

(2012) James E. Johnson Jr et al.   NATURE

Good vibrations in enzyme-catalysed reactions

(2012) Sam Hay et al.   Nature Chemistry

Taking Ockham's razor to enzyme dynamics and catalysis

(2012) David R. Glowacki et al.   Nature Chemistry

Is There a Dynamic Protein Contribution to the Substrate Trigger in Coenzyme B12-Dependent Ethanolamine Ammonia Lyase?

(2011) Alex R. Jones et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Vitamin B12-derivatives—enzyme cofactors and ligands of proteins and nucleic acids

(2011) Karl Gruber et al.   CHEMICAL SOCIETY REVIEWS

The Fragmentation–Recombination Mechanism of the Enzyme Glutamate Mutase Studied by QM/MM Simulations

(2011) Judith B. Rommel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of Protein Contributions to Cobalt−Carbon Bond Cleavage Catalysis in Adenosylcobalamin-Dependent Ethanolamine Ammonia-Lyase by using Photolysis in the Ternary Complex

(2011) Wesley D. Robertson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Large-Scale Domain Conformational Change Is Coupled to the Activation of the Co–C Bond in the B12-Dependent Enzyme Ornithine 4,5-Aminomutase: A Computational Study

(2011) Jiayun Pang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light-dependent gene regulation by a coenzyme B12-based photoreceptor

(2011) J. M. Ortiz-Guerrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Femtosecond dynamics coupled to chemical barrier crossing in a Born-Oppenheimer enzyme

(2011) R. G. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen Tunneling in Adenosylcobalamin-Dependent Glutamate Mutase: Evidence from Intrinsic Kinetic Isotope Effects Measured by Intramolecular Competition

(2010) Miri Yoon et al.   BIOCHEMISTRY

Barrier Compression and Its Contribution to Both Classical and Quantum Mechanical Aspects of Enzyme Catalysis

(2010) Sam Hay et al.   BIOPHYSICAL JOURNAL

Adenosyl Radical: Reagent and Catalyst in Enzyme Reactions

(2010) E. Neil G. Marsh et al.   CHEMBIOCHEM

Large-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-Aminomutase

(2010) Kirsten R. Wolthers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of the Human GTPase MMAA and Vitamin B12-dependent Methylmalonyl-CoA Mutase and Insight into Their Complex Formation

(2010) D. Sean Froese et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of Ethanolamine Ammonia-lyase Complexed with Coenzyme B12Analogs and Substrates

(2010) Naoki Shibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Time-resolved studies of radical pairs

(2009) Jonathan R. Woodward et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Solvent-Dependent Cage Dynamics of Small Nonpolar Radicals: Lessons from the Photodissociation and Geminate Recombination of Alkylcobalamins

(2009) Andrew B. Stickrath et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Continuous Wave Photolysis Magnetic Field Effect Investigations with Free and Protein-Bound Alkylcobalamins

(2009) Alex R. Jones et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identification of the Substrate Radical Intermediate Derived from Ethanolamine during Catalysis by Ethanolamine Ammonia-Lyase†

(2008) Güneş Bender et al.   BIOCHEMISTRY

Photolysis of Adenosylcobalamin and Radical Pair Recombination in Ethanolamine Ammonia-Lyase Probed on the Micro- to Millisecond Time Scale by Using Time-Resolved Optical Absorption Spectroscopy†

(2008) Wesley D. Robertson et al.   BIOCHEMISTRY

Cobalamin-dependent and cobamide-dependent methyltransferases

(2008) Rowena G Matthews et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

An update on cobalamin deficiency in adults

(2008) N. Dali-Youcef et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE