Unique ganglioside binding by botulinum neurotoxins C and D-SA

Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner

(2010) Jasmin Strotmeier et al.   BIOCHEMICAL JOURNAL

Molecular mechanisms of substrate recognition and specificity of botulinum neurotoxin serotype F

(2010) Sheng Chen et al.   BIOCHEMICAL JOURNAL

Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA,

(2010) Andrew P.-A. Karalewitz et al.   BIOCHEMISTRY

Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F

(2009) Zhuji Fu et al.   BIOCHEMISTRY

Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

(2009) Chen Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor

(2009) Andreas Rummel et al.   JOURNAL OF NEUROCHEMISTRY

Mode of VAMP substrate recognition and inhibition of Clostridium botulinum neurotoxin F

(2009) Rakhi Agarwal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Engineering botulinum neurotoxin to extend therapeutic intervention

(2009) S. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SNAP-25 Substrate Peptide (Residues 180–183) Binds to but Bypasses Cleavage by Catalytically ActiveClostridium botulinumNeurotoxin E

(2008) Rakhi Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Domain Organization in Clostridium botulinum Neurotoxin Type E Is Unique: Its Implication in Faster Translocation

(2008) Desigan Kumaran et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of the receptor-binding sites in the carboxyl-terminal half of the heavy chain of botulinum neurotoxin types C and D

(2008) Kentaro Tsukamoto et al.   MICROBIAL PATHOGENESIS

Glycosylated SV2A and SV2B Mediate the Entry of Botulinum Neurotoxin E into Neurons

(2008) Min Dong et al.   MOLECULAR BIOLOGY OF THE CELL

Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction

(2008) Pål Stenmark et al.   PLoS Pathogens

Botulinum Neurotoxin Devoid of Receptor Binding Domain Translocates Active Protease

(2008) Audrey Fischer et al.   PLoS Pathogens

Immune recognition of botulinum neurotoxin B: Antibody-binding regions on the heavy chain of the toxin

(2007) Behzod Z. Dolimbek et al.   MOLECULAR IMMUNOLOGY