Mechanisms of amyloid fibril formation - focus on domain-swapping

Mechanism of amyloidogenesis: nucleation-dependent fibrillation versus double-concerted fibrillation

(2011) Ghi-Bom Bhak et al.   BMB Reports

Applying Hsp104 to protein-misfolding disordersThis paper is one of a selection of papers published in this special issue entitled 8th International Conference on AAA Proteins and has undergone the Journal's usual peer review process.

(2010) Shilpa Vashist et al.   Biochemistry and Cell Biology

Amyloid fibril formation by human stefins: Structure, mechanism & putative functions

(2010) Eva Žerovnik et al.   BIOCHIMIE

Crystal structure of human cystatin C stabilized against amyloid formation

(2010) Robert Kolodziejczyk et al.   FEBS Journal

Mysterious oligomerization of the amyloidogenic proteins

(2010) Vladimir N. Uversky   FEBS Journal

Intrinsic disorder in proteins associated with neurodegenerative diseases

(2010) Vladimir et al.   Frontiers in Bioscience-Landmark

A Hinge Region cis-Proline in Ribonuclease A Acts as a Conformational Gatekeeper for C-Terminal Domain Swapping

(2010) Katherine H. Miller et al.   JOURNAL OF MOLECULAR BIOLOGY

Autophagy gone awry in neurodegenerative diseases

(2010) Esther Wong et al.   NATURE NEUROSCIENCE

β2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages

(2010) Cong Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Induction of Autophagy by Cystatin C: A Mechanism That Protects Murine Primary Cortical Neurons and Neuronal Cell Lines

(2010) Belen Tizon et al.   PLoS One

Identifying the amylome, proteins capable of forming amyloid-like fibrils

(2010) Lukasz Goldschmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biological metals and Alzheimer's disease: Implications for therapeutics and diagnostics

(2010) James A. Duce et al.   PROGRESS IN NEUROBIOLOGY

Non-3D domain swapped crystal structure of truncated zebrafish alphaA crystallin

(2010) A. Laganowsky et al.   PROTEIN SCIENCE

Amyloid β-Protein Aggregation Produces Highly Reproducible Kinetic Data and Occurs by a Two-Phase Process

(2009) Erik Hellstrand et al.   ACS Chemical Neuroscience

Delineating the Conformational Elements Responsible for Cu2+-Induced Oligomerization of β-2 Microglobulin

(2009) Dorottya V. Blaho et al.   BIOCHEMISTRY

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

(2009) Liping Yu et al.   BIOCHEMISTRY

Amyloid Fibril-Like Structure Underlies the Aggregate Structure across the pH Range for β -Lactoglobulin

(2009) Mark R.H. Krebs et al.   BIOPHYSICAL JOURNAL

Phylogenomic analysis of the cystatin superfamily in eukaryotes and prokaryotes

(2009) Dušan Kordiš et al.   BMC EVOLUTIONARY BIOLOGY

TheCST3B haplotype is associated with frontotemporal lobar degeneration

(2009) L. Benussi et al.   EUROPEAN JOURNAL OF NEUROLOGY

Essential role of Pro 74 in stefin B amyloid-fibril formation: Dual action of cyclophilin A on the process

(2009) Aida Smajlović et al.   FEBS LETTERS

Methods for structural characterization of prefibrillar intermediates and amyloid fibrils

(2009) Annette Eva Langkilde et al.   FEBS LETTERS

Cystatin B Deficiency Sensitizes Neurons to Oxidative Stress in Progressive Myoclonus Epilepsy, EPM1

(2009) M. K. Lehtinen et al.   JOURNAL OF NEUROSCIENCE

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

(2009) Ashwani K Thakur et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Granular Assembly of α-Synuclein Leading to the Accelerated Amyloid Fibril Formation with Shear Stress

(2009) Ghibom Bhak et al.   PLoS One

Remodeling of Protein Aggregates by Hsp104

(2009) John Glover et al.   PROTEIN AND PEPTIDE LETTERS

Size and morphology of toxic oligomers of amyloidogenic proteins: a case study of human stefin B

(2008) Slavko Čeru et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Protein aggregation kinetics, mechanism, and curve-fitting: A review of the literature

(2008) Aimee M. Morris et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Instantaneous Amyloid Fibril Formation of α-Synuclein from the Oligomeric Granular Structures in the Presence of Hexane

(2008) Jung-Ho Lee et al.   BIOPHYSICAL JOURNAL

Cystatins: Biochemical and structural properties, and medical relevance

(2008) ">Vito Turk   Frontiers in Bioscience-Landmark

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein aggregation probed by two-photon fluorescence correlation spectroscopy of native tryptophan

(2008) Bankanidhi Sahoo et al.   JOURNAL OF CHEMICAL PHYSICS

Hsp104 Targets Multiple Intermediates on the Amyloid Pathway and Suppresses the Seeding Capacity of Aβ Fibrils and Protofibrils

(2008) Muriel Arimon et al.   JOURNAL OF MOLECULAR BIOLOGY

Conformational Conversion May Precede or Follow Aggregate Elongation on Alternative Pathways of Amyloid Protofibril Formation

(2008) Santosh Kumar et al.   JOURNAL OF MOLECULAR BIOLOGY

Competition between Folding, Native-State Dimerisation and Amyloid Aggregation in β-Lactoglobulin

(2008) Daizo Hamada et al.   JOURNAL OF MOLECULAR BIOLOGY

Determination of Conformational Preferences of Dipeptides Using Vibrational Spectroscopy

(2008) Jože Grdadolnik et al.   JOURNAL OF PHYSICAL CHEMISTRY B

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(2008) G Irvine et al.   MOLECULAR MEDICINE

A regulatable switch mediates self-association in an immunoglobulin fold

(2008) Matthew F Calabrese et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Therapeutics for Alzheimer’s disease based on the metal hypothesis

(2008) Ashley I. Bush et al.   Neurotherapeutics

The mechanism of amyloid-fibril formation by stefin B: Temperature and protein concentration dependence of the rates

(2008) Katja Škerget et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Mechanisms of Protein Fibril Formation: Nucleated Polymerization with Competing Off-Pathway Aggregation

(2007) Evan T. Powers et al.   BIOPHYSICAL JOURNAL

Exclusion of the Native α-Helix from the Amyloid Fibrils of a Mixed α/β Protein

(2007) Gareth J. Morgan et al.   JOURNAL OF MOLECULAR BIOLOGY