Multi-targeted activity of maslinic acid as an antimalarial natural compound

Investigation of a novel approach to scoring Giemsa-stained malaria-infected thin blood films

(2012) Owen Proudfoot et al.   MALARIA JOURNAL

Parasitostatic effect of maslinic acid. I. Growth arrest of Plasmodium falciparum intraerythrocytic stages

(2011) Carlos Moneriz et al.   MALARIA JOURNAL

Parasitostatic effect of maslinic acid. II. Survival increase and immune protection in lethal Plasmodium yoelii-infected mice

(2011) Carlos Moneriz et al.   MALARIA JOURNAL

Empowering malaria vaccination by drug administration

(2010) Robert W Sauerwein et al.   CURRENT OPINION IN IMMUNOLOGY

Action of a Pentacyclic Triterpenoid, Maslinic Acid, againstToxoplasma gondii

(2010) Luis M. De Pablos et al.   JOURNAL OF NATURAL PRODUCTS

Plasmodium falciparum PfA-M1 aminopeptidase is trafficked via the parasitophorous vacuole and marginally delivered to the food vacuole

(2010) Omid Azimzadeh et al.   MALARIA JOURNAL

In Silico Receptorome Screening of Antipsychotic Drugs

(2010) David Vidal et al.   Molecular Informatics

The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis

(2010) Freya J. I. Fowkes et al.   PLOS MEDICINE

Synthesis and biological evaluation of heterocyclic ring-substituted maslinic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B

(2009) Wen-Wei Qiu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A chemogenomic approach to drug discovery: focus on cardiovascular diseases

(2009) Montserrat Cases et al.   DRUG DISCOVERY TODAY

A multifunctional serine protease primes the malaria parasite for red blood cell invasion

(2009) Konstantinos Koussis et al.   EMBO JOURNAL

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum

(2009) Jing Yuan et al.   Nature Chemical Biology

Synchronous culture of Plasmodium falciparum at high parasitemia levels

(2009) Azar Radfar et al.   Nature Protocols

MEROPS: the peptidase database

(2009) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Selective and Irreversible Inhibitors of Mosquito Acetylcholinesterases for Controlling Malaria and Other Mosquito-Borne Diseases

(2009) Yuan-Ping Pang et al.   PLoS One

Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials

(2009) Tina S. Skinner-Adams et al.   TRENDS IN BIOCHEMICAL SCIENCES

Conciliating binding efficiency and polypharmacology

(2009) Jordi Mestres et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Antimalarial Drugs – What is in Use and What is in the Pipeline

(2008) Martin Schlitzer   ARCHIV DER PHARMAZIE

Solution- and solid-phase synthesis and anti-HIV activity of maslinic acid derivatives containing amino acids and peptides

(2008) Andres Parra et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Malarial proteases and host cell egress: an ‘emerging’ cascade

(2008) Michael J. Blackman   CELLULAR MICROBIOLOGY

A Ligand-Based Approach to Mining the Chemogenomic Space of Drugs

(2008) Elisabet Gregori-Puigjane et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Inhibition of Malaria Parasite Development by a Cyclic Peptide That Targets the Vital Parasite Protein SERA5

(2008) W. D. Fairlie et al.   INFECTION AND IMMUNITY

Naturally Occurring Pentacyclic Triterpenes as Inhibitors of Glycogen Phosphorylase: Synthesis, Structure−Activity Relationships, and X-ray Crystallographic Studies†

(2008) Xiaoan Wen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Data completeness—the Achilles heel of drug-target networks

(2008) Jordi Mestres et al.   NATURE BIOTECHNOLOGY

Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum

(2008) Shirin Arastu-Kapur et al.   Nature Chemical Biology