BRICHOS domain associated with lung fibrosis, dementia and cancer - a chaperone that prevents amyloid fibril formation?

Amyloid fibril protein nomenclature: 2010 recommendations from the nomenclature committee of the International Society of Amyloidosis

(2010) Jean D. Sipe et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Conformational preferences of non-polar amino acid residues: An additional factor in amyloid formation

(2010) Jan Johansson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Novel Gastrokine, Gkn3, Marks Gastric Atrophy and Shows Evidence of Adaptive Gene Loss in Humans

(2010) Trevelyan R. Menheniott et al.   GASTROENTEROLOGY

Memory Deficits Due to Familial British Dementia BRI2 Mutation Are Caused by Loss of BRI2 Function Rather than Amyloidosis

(2010) R. Tamayev et al.   JOURNAL OF NEUROSCIENCE

Bri2-23 is a potential cerebrospinal fluid biomarker in multiple sclerosis

(2010) Violaine K. Harris et al.   NEUROBIOLOGY OF DISEASE

Stabilization of neurotoxic Alzheimer amyloid-  oligomers by protein engineering

(2010) A. Sandberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits

(2010) R. Tamayev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease

(2010) Janaky Coomaraswamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The extracellular domain of Bri2 (ITM2B) binds the ABri peptide (1–23) and amyloid β-peptide (Aβ1–40): Implications for Bri2 effects on processing of amyloid precursor protein and Aβ aggregation

(2009) Siwei Peng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-Amyloid Activity of the C-Terminal Domain of proSP-C against Amyloid β-Peptide and Medin†

(2009) Charlotte Nerelius et al.   BIOCHEMISTRY

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

(2009) Liping Yu et al.   BIOCHEMISTRY

C-terminal, endoplasmic reticulum-lumenal domain of prosurfactant protein C - structural features and membrane interactions

(2009) Cristina Casals et al.   FEBS Journal

BRI3 Inhibits Amyloid Precursor Protein Processing in a Mechanistically Distinct Manner from Its Homologue Dementia Gene BRI2

(2009) Shuji Matsuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preventing Amyloid Formation by Catching Unfolded Transmembrane Segments

(2009) H. Johansson et al.   JOURNAL OF MOLECULAR BIOLOGY

The Brichos domain of prosurfactant protein C can hold and fold a transmembrane segment

(2009) Hanna Johansson et al.   PROTEIN SCIENCE

Mutations linked to interstitial lung disease can abrogate anti-amyloid function of prosurfactant protein C

(2008) Charlotte Nerelius et al.   BIOCHEMICAL JOURNAL

Structure and mode of action of the antimicrobial peptide arenicin

(2008) Jörg Andrä et al.   BIOCHEMICAL JOURNAL

Protease Activation of α2-Macroglobulin Modulates a Chaperone-like Action with Broad Specificity

(2008) Katie French et al.   BIOCHEMISTRY

Cerebral Amyloid Angiopathy and Parenchymal Amyloid Deposition in Transgenic Mice Expressing the Danish Mutant Form of Human BRI2

(2008) Ruben Vidal et al.   BRAIN PATHOLOGY

Hsp104 Targets Multiple Intermediates on the Amyloid Pathway and Suppresses the Seeding Capacity of Aβ Fibrils and Protofibrils

(2008) Muriel Arimon et al.   JOURNAL OF MOLECULAR BIOLOGY

BRI2 Inhibits Amyloid  -Peptide Precursor Protein Processing by Interfering with the Docking of Secretases to the Substrate

(2008) S. Matsuda et al.   JOURNAL OF NEUROSCIENCE

BRI2 (ITM2b) Inhibits A  Deposition In Vivo

(2008) J. Kim et al.   JOURNAL OF NEUROSCIENCE

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE