Review
Plant Sciences
Yunzhuan Zhou, Fuxiang Xu, Yanan Shao, Junna He
Summary: As global warming intensifies, the earth's average temperature continues to rise. Plants have developed two main mechanisms, the heat stress response and the thermomorphogenesis response, to cope with elevated temperatures. This review summarizes recent progress in understanding these heat-responsive molecular regulatory pathways in plants and discusses future perspectives in this field.
Article
Plant Sciences
Shujun Meng, Yuming Huang, Yujie Lian, Hui Chen, Xudong Cao, Dong Ding, Xiaoyang Chen, Jihua Tang
Summary: The study identified differentially expressed genes associated with maize ear-length development and highlighted the importance of transcription factors and heat shock proteins. These findings provide candidate genes for dissecting the molecular mechanisms of ear-length development and increasing maize ear length.
PLANT GROWTH REGULATION
(2023)
Article
Biochemistry & Molecular Biology
Guangna Chen, Hongliang Hu, Xinhui Chen, Jialuo Chen, Siyi Wang, He Ning, Cheng Zhu, Su Yang
Summary: TFIIB is a general transcription factor that plays a crucial role in RNA polymerase II activity. In plants, the TFIIB-related protein family, including BRP5/PTF2, has expanded greatly. This study revealed the essential role of BRP5/PTF2 in pollen germination and embryogenesis in Arabidopsis and its impact on pollen development and grain formation in rice. These findings highlight the importance of BRP5/PTF2 in plant sexual reproduction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Zhenyu Ma, Mingyue Li, Huaning Zhang, Baihui Zhao, Zihui Liu, Shuonan Duan, Xiangzhao Meng, Guoliang Li, Xiulin Guo
Summary: High temperature reduces crop production, especially wheat. A novel splice variant, TaHsfA2-7-AS, was induced by heat and positively regulated thermotolerance in wheat. TaHsfA2-7-AS encodes a truncated isoform and its expression is up-regulated during heat shock.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Abdulhakim A. Aldubai, Abdullah A. Alsadon, Hussein H. Migdadi, Salem S. Alghamdi, Sulieman A. Al-Faifi, Muhammad Afzal
Summary: This study aimed to determine the response of tomato to heat stress under different temperature conditions and characterized the heat shock genes in tomato genotypes. The results showed that heat shock factor genes play an important role in plant heat tolerance pathways, and different genotypes have different responses to high-temperature stress.
Review
Plant Sciences
Fengxia Tian, Xiao-Li Hu, Tao Yao, Xiaohan Yang, Jin-Gui Chen, Meng-Zhu Lu, Jin Zhang
Summary: Global warming poses a threat to plant life, with heat shock response (HSR) playing a crucial role in protecting cellular homeostasis, especially for perennial trees. Understanding the molecular mechanisms of HSR in woody plants is essential for predicting how they will respond to climate changes.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Plant Sciences
Kunliang Xie, Jinliang Guo, Shaoyu Wang, Wenjie Ye, Fengli Sun, Chao Zhang, Yajun Xi
Summary: This study identified the Hsf family in switchgrass and revealed its functional role in heat stress signal transduction and heat tolerance. PvHsf03 and PvHsf25 were found to play critical roles in the early and late stages of switchgrass response to heat stress, respectively, while HsfB mainly showed a negative response to heat stress. Additionally, ectopic expression of PvHsf03 significantly increased the heat resistance of Arabidopsis seedlings. This research provides a notable foundation for studying the regulatory network in response to deleterious environments and for further excavating tolerance genes in switchgrass.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Pia Roos-Mattjus, Lea Sistonen
Summary: Heat-shock factors (HSFs) are a family of transcription factors with a wide range of target genes, playing crucial roles in normal development and linked to various diseases such as neurodegenerative disorders and cancer. The regulatory mechanisms of HSFs and their specific target gene selection under different conditions remain unclear, with posttranslational modifications and interplay among family members being key regulatory mechanisms.
Article
Plant Sciences
Quanquan Shen, Qian Chen, Yang Liu, Xiang Xue, Xiaogang Shen, Qiang He, Guokun Wang, Fei Han
Summary: Aspirin can partially alleviate vascular smooth muscle cell (VSMC) calcification by regulating the expression of heat shock protein 70 (HSP70) and heat shock protein 90 (HSP90). Blocking HSP70 or HSP90 inhibitors can partially weaken the anti-calcification effect of aspirin.
PHARMACEUTICAL BIOLOGY
(2022)
Article
Cell Biology
Mooud Amirkavei, Flavia Plastino, Anders Kvanta, Kai Kaarniranta, Helder Andre, Ari Koskelainen
Summary: Cells have stress-response pathways to cope with stress factors for homeostasis maintenance; low doses of stress may be beneficial; HHS was found to enhance autophagy gene expression and activation through HSF1.
Article
Biochemistry & Molecular Biology
Ting-Ting Sun, Chao Wang, Rui Liu, Yu Zhang, Yu-Cheng Wang, Liu-Qiang Wang
Summary: This study elucidated the regulatory mechanism of ThHSFA1-ThWRKY4 genes in response to salt stress in Tamarix hispida, with ThHSFA1 acting as an upstream regulator that can directly activate ThWRKY4 expression. Transgenic plants overexpressing ThHSFA1 exhibited enhanced salt tolerance, decreased reactive oxygen species levels, and increased antioxidant enzyme activity levels under salt stress.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Mengyao Li, Ran Zhang, Jin Zhou, Jiageng Du, Xiaoyan Li, Yong Zhang, Qing Chen, Yan Wang, Yuanxiu Lin, Yunting Zhang, Wen He, Xiaorong Wang, Aisheng Xiong, Ya Luo, Haoru Tang
Summary: High temperature stress is a significant abiotic stress that affects natural habitats and agriculturally significant plants worldwide. The HSF family is an important transcription factor family in plants that responds rapidly to heat and other abiotic stresses. This study identified and classified 29 AgHSFs in celery, and demonstrated their involvement in multiple biological processes. The functional validation of AgHSFa6-1 confirmed its role as a positive regulator in response to high temperature, enhancing thermotolerance in yeast and Arabidopsis and improving celery's thermotolerance through various mechanisms.
FRONTIERS IN PLANT SCIENCE
(2023)
Review
Plant Sciences
Baptiste Bourgine, Anthony Guihur
Summary: Heat stress events limit crop productivity, leading plants to accumulate heat-shock proteins (HSPs) for thermal protection. HSP chaperones play a critical role in regulating protein folding and preventing misfolded protein formation, thereby avoiding heat-induced cell death. The HSP20 family is tightly repressed at low temperatures, suggesting a costly mechanism that can become detrimental under unnecessary conditions.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Chengcheng Ling, Yunyan Liu, Zuchi Yang, Jiale Xu, Zhiyin Ouyang, Jun Yang, Songhu Wang
Summary: This study conducted a comprehensive analysis of the AeHSF gene family in kiwifruit and found that AeHSFA2b can enhance the tolerance of kiwifruit to salt stress by directly binding to the AeRFS4 promoter.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Gaelle Friocourt, Aurore Perrin, Paul A. Saunders, Elvira Nikalayevich, Cecile Voisset, Charles Coutton, Guillaume Martinez, Frederic Morel
Summary: Mendel's law of segregation states that alleles at a diploid locus should be equally transmitted to the progeny. Genetic segregation distortion, known as transmission ratio distortion (TRD), is a deviation from this rule and has been observed in several mammal species. This review provides examples of TRD in mammals and discusses the mechanisms behind it, with a focus on the differences between male and female gametogenesis in mice. It also explores TRD in other mammals, including farmed species and the common shrew, and discusses its relevance to human diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)