ERK and cell death: ERK location and T cell selection

Protein Kinase C-  Is Required for Efficient Positive Selection

(2014) S. C. Morley et al.   JOURNAL OF IMMUNOLOGY

Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells

(2009) Jayajit Das et al.   CELL

The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development

(2009) Amanda L. Prince et al.   IMMUNOLOGICAL REVIEWS

The Mitogen-Activated Protein Kinase Scaffold KSR1 Is Required for Recruitment of Extracellular Signal-Regulated Kinase to the Immunological Synapse

(2009) E. Giurisato et al.   MOLECULAR AND CELLULAR BIOLOGY

Non-redundant function of the MEK5–ERK5 pathway in thymocyte apoptosis

(2008) Sue J Sohn et al.   EMBO JOURNAL

ERK5 is involved in TCR-induced apoptosis through the modification of Nur77

(2008) Yasushi Fujii et al.   GENES TO CELLS

During negative selection, Nur77 family proteins translocate to mitochondria where they associate with Bcl-2 and expose its proapoptotic BH3 domain

(2008) Jennifer Thompson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Scalable signaling mediated by T cell antigen receptor–CD3 ITAMs ensures effective negative selection and prevents autoimmunity

(2008) Jeff Holst et al.   NATURE IMMUNOLOGY

Origin of the sharp boundary that discriminates positive and negative selection of thymocytes

(2008) A. Prasad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA