Vascular characterization of mice with endothelial expression of cytochrome P450 4F2

Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients

(2013) Robert N. Schuck et al.   ATHEROSCLEROSIS

Induction of Angiotensin-Converting Enzyme and Activation of the Renin–Angiotensin System Contribute to 20-Hydroxyeicosatetraenoic Acid–Mediated Endothelial Dysfunction

(2012) Jennifer Cheng et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Disturbed ratio of renal 20-HETE/EETs is involved in androgen-induced hypertension in cytochrome P450 4F2 transgenic mice

(2012) Xiaoliang Liu et al.   GENE

Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart

(2011) Matthew L. Edin et al.   FASEB JOURNAL

20-HETE increases NADPH oxidase-derived ROS production and stimulates the L-type Ca2+ channel via a PKC-dependent mechanism in cardiomyocytes

(2010) Qinghua Zeng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cytochrome P450 ω-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer

(2010) Wei Yu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice

(2010) Craig R. Lee et al.   FASEB JOURNAL

Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury

(2010) Uwe Hoff et al.   KIDNEY INTERNATIONAL

CYP4F2 gene V433M polymorphism is associated with ischemic stroke in the male Northern Chinese Han population

(2010) Shumin Deng et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

20-HETE can act as a nonhypoxic regulator of HIF-1α in human microvascular endothelial cells

(2009) Austin M. Guo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

NADPH Oxidases: Functions and Pathologies in the Vasculature

(2009) Bernard Lassègue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

20-Hydroxy-5,8,11,14-eicosatetraenoic Acid Mediates Endothelial Dysfunction via I B Kinase-Dependent Endothelial Nitric-Oxide Synthase Uncoupling

(2009) J. Cheng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic acid production and arterial blood pressure

(2009) Xiaoliang Liu et al.   KIDNEY INTERNATIONAL

20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells

(2008) Meetha Medhora et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Increased blood pressure in mice lacking cytochrome P450 2J5

(2008) Krairerk Athirakul et al.   FASEB JOURNAL

A Single Nucleotide Polymorphism in the CYP4F2 but not CYP4A11 Gene Is Associated With Increased 20-HETE Excretion and Blood Pressure

(2008) Natalie C. Ward et al.   HYPERTENSION

Interleukin-6 Mediates the Increase in NADPH-Oxidase in the Ketamine Model of Schizophrenia

(2008) M. M. Behrens et al.   JOURNAL OF NEUROSCIENCE

20-HETE Mediates Proliferation of Renal Epithelial Cells in Polycystic Kidney Disease

(2008) F. Park et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Association of a Functional Cytochrome P450 4F2 Haplotype with Urinary 20-HETE and Hypertension

(2008) H. Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

20-Hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling

(2007) Jennifer Cheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY