Amyloid precursor protein α- and β-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2
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Title
Amyloid precursor protein α- and β-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2
Authors
Keywords
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Journal
FASEB JOURNAL
Volume 28, Issue 2, Pages 849-860
Publisher
FASEB
Online
2013-11-19
DOI
10.1096/fj.13-239301
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- (2011) Frank W. Pfrieger et al. PROGRESS IN LIPID RESEARCH
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- (2010) H. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) Joseph L. Goldstein et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
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- (2009) Y. Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2007) Piia Simonen et al. ATHEROSCLEROSIS
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- (2007) Huaqi Xiong et al. NEUROBIOLOGY OF DISEASE
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