Senescence-associated release of transmembrane proteins involves proteolytic processing by ADAM17 and microvesicle shedding

Cellular senescence and its effector programs

(2014) R. Salama et al.   GENES & DEVELOPMENT

Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR)

(2013) Christoph Garbers et al.   CELL CYCLE

I B  is a regulator of the senescence-associated secretory phenotype in DNA damage- and oncogene-induced senescence

(2013) E. Alexander et al.   JOURNAL OF CELL SCIENCE

A novel bispecific single-chain antibody for ADAM17 and CD3 induces T-cell-mediated lysis of prostate cancer cells

(2012) Kosuke Yamamoto et al.   BIOCHEMICAL JOURNAL

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

(2011) Adam Freund et al.   EMBO JOURNAL

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

Development of sandwich ELISA for detection and quantification of human and murine a disintegrin and metalloproteinase17

(2011) Ahmad Trad et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Cross-domain inhibition of TACE ectodomain

(2011) C. J. Tape et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADAM17: a molecular switch to control inflammation and tissue regeneration

(2011) Jürgen Scheller et al.   TRENDS IN IMMUNOLOGY

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

(2010) E. Jorissen et al.   JOURNAL OF NEUROSCIENCE

Direct Activation of TACE-Mediated Ectodomain Shedding by p38 MAP Kinase Regulates EGF Receptor-Dependent Cell Proliferation

(2010) Pinglong Xu et al.   MOLECULAR CELL

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

(2010) Jean-Philippe Coppé et al.   PLoS One

Inflammatory networks during cellular senescence: causes and consequences

(2010) Adam Freund et al.   TRENDS IN MOLECULAR MEDICINE

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Senescence-Associated Exosome Release from Human Prostate Cancer Cells

(2008) B. D. Lehmann et al.   CANCER RESEARCH

Multiple Mechanisms Are Responsible for Transactivation of the Epidermal Growth Factor Receptor in Mammary Epithelial Cells

(2008) Karin D. Rodland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pervanadate-induced shedding of the intercellular adhesion molecule (ICAM)-1 ectodomain is mediated by membrane type-1 matrix metalloproteinase (MT1-MMP)

(2008) E. Essick et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY