Loss of sphingosine kinase 1 predisposes to the onset of diabetes via promoting pancreatic β-cell death in diet-induced obese mice

Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 β-cell survival

(2012) Julien Véret et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Diabetes Mellitus and the β Cell: The Last Ten Years

(2012) Frances M. Ashcroft et al.   CELL

Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress-Mitochondrial Dialog Triggering Lipotoxic Rodent and Human  -Cell Apoptosis

(2012) D. A. Cunha et al.   DIABETES

Overexpression of Sphingosine Kinase 1 Prevents Ceramide Accumulation and Ameliorates Muscle Insulin Resistance in High-Fat Diet-Fed Mice

(2012) C. R. Bruce et al.   DIABETES

Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Plays a Critical Role in β-Cell Survival under Endoplasmic Reticulum Stress

(2012) Yanfei Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MMSAT: Automated Quantification of Metabolites in Selected Reaction Monitoring Experiments

(2011) Jason W. H. Wong et al.   ANALYTICAL CHEMISTRY

Sphingosine kinase 1 knockdown reduces insulin synthesis and secretion in a rat insulinoma cell line

(2011) N.M. Hasan et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A lipidomic screen of palmitate-treated MIN6 β-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking

(2011) Ebru Boslem et al.   BIOCHEMICAL JOURNAL

Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction

(2011) Esteban N. Gurzov et al.   TRENDS IN CELL BIOLOGY

Sphingosine-1-phosphate signaling and its role in disease

(2011) Michael Maceyka et al.   TRENDS IN CELL BIOLOGY

Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies

(2010) Adria Giacca et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis

(2010) F Allagnat et al.   CELL DEATH AND DIFFERENTIATION

Assessment of Feeding Behavior in Laboratory Mice

(2010) Kate L.J. Ellacott et al.   Cell Metabolism

Sphingosine 1-phosphate, a key mediator of the cytokine network: Juxtacrine signaling

(2010) Pu Xia et al.   CYTOKINE & GROWTH FACTOR REVIEWS

 -Cell Growth and Regeneration: Replication Is Only Part of the Story

(2010) S. Bonner-Weir et al.   DIABETES

Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice

(2010) Ana Olivera et al.   JOURNAL OF CLINICAL INVESTIGATION

Glucolipotoxicity of the pancreatic beta cell

(2009) Vincent Poitout et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Restoring Endocrine Response in Breast Cancer Cells by Inhibition of the Sphingosine Kinase-1 Signaling Pathway

(2009) Olga Sukocheva et al.   ENDOCRINOLOGY

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

(2009) Mira M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet

(2008) Chie Ebato et al.   Cell Metabolism

Inhibition of Foxo1 Protects Pancreatic Islet  -Cells Against Fatty Acid and Endoplasmic Reticulum Stress-Induced Apoptosis

(2008) S. C. Martinez et al.   DIABETES

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY