Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation

Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation

(2013) Brendan Egan et al.   Cell Metabolism

Simple estimators of false discovery rates given as few as one or two p-values without strong parametric assumptions

(2013) David R. Bickel   Statistical Applications in Genetics and Molecular Biology

Muscle-Specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility

(2012) Deborah M. Muoio et al.   Cell Metabolism

Calorie restriction in mice overexpressing UCP3: Evidence that prior mitochondrial uncoupling alters response

(2012) Carmen Estey et al.   EXPERIMENTAL GERONTOLOGY

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

(2012) S. A. Hawley et al.   SCIENCE

Estimators of the local false discovery rate designed for small numbers of tests

(2012) Marta Padilla et al.   Statistical Applications in Genetics and Molecular Biology

Hexokinase II acts through UCP3 to suppress mitochondrial reactive oxygen species production and maintain aerobic respiration

(2011) Ryan J. Mailloux et al.   BIOCHEMICAL JOURNAL

Crucial yet divergent roles of mitochondrial redox state in skeletal muscle vs. brown adipose tissue energetics

(2011) Ryan J. Mailloux et al.   FASEB JOURNAL

Metabolic profiling of muscle contraction in lean compared with obese rodents

(2010) John P. Thyfault et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Abnormal metabolism flexibility in response to high palmitate concentrations in myotubes derived from obese type 2 diabetic patients

(2010) Magali Kitzmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Intramyocellular lipid accumulation is associated with permanent relocation ex vivo and in vitro of fatty acid translocase (FAT)/CD36 in obese patients

(2010) C. Aguer et al.   DIABETOLOGIA

Uncoupling protein-3 lowers reactive oxygen species production in isolated mitochondria

(2010) Laurence J. Toime et al.   FREE RADICAL BIOLOGY AND MEDICINE

Distinct skeletal muscle fiber characteristics and gene expression in diet-sensitive versus diet-resistant obesity

(2010) Martin F. Gerrits et al.   JOURNAL OF LIPID RESEARCH

Uncoupling protein 3 expression levels influence insulin sensitivity, fatty acid oxidation, and related signaling pathways

(2010) Rosalba Senese et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Long-Chain Fatty Acid Combustion Rate Is Associated with Unique Metabolite Profiles in Skeletal Muscle Mitochondria

(2010) Erin L. Seifert et al.   PLoS One

Medium Chain Acylcarnitines Dominate the Metabolite Pattern in Humans under Moderate Intensity Exercise and Support Lipid Oxidation

(2010) Rainer Lehmann et al.   PLoS One

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism

(2009) Kristaps Jaudzems et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Plasma Acylcarnitine Profiles Suggest Incomplete Long-Chain Fatty Acid β-Oxidation and Altered Tricarboxylic Acid Cycle Activity in Type 2 Diabetic African-American Women

(2009) Sean H. Adams et al.   JOURNAL OF NUTRITION

AMPK and PPARδ Agonists Are Exercise Mimetics

(2008) Vihang A. Narkar et al.   CELL

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Muscle-specific expression of PPARγ coactivator-1α improves exercise performance and increases peak oxygen uptake

(2008) Jennifer A. Calvo et al.   JOURNAL OF APPLIED PHYSIOLOGY

Acute exercise increases expression of extracellular superoxide dismutase in skeletal muscle and the aorta

(2008) Yoshiaki Hitomi et al.   REDOX REPORT

PGC-1α is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle

(2007) Lotte Leick et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM