Defective DNA damage response and repair in liver cells expressing hepatitis B virus surface antigen

Multicenter results of stereotactic body radiotherapy (SBRT) for non-resectable primary liver tumors

(2012) Rafael A. Ibarra et al.   ACTA ONCOLOGICA

Targeting the DNA damage response in oncology

(2012) Bristi Basu et al.   CURRENT OPINION IN ONCOLOGY

Zinc Fingers and Homeoboxes 2 Inhibits Hepatocellular Carcinoma Cell Proliferation and Represses Expression of Cyclins A and E

(2012) Xuetian Yue et al.   GASTROENTEROLOGY

High Levels of Hepatitis B Surface Antigen Increase Risk of Hepatocellular Carcinoma in Patients With Low HBV Load

(2012) Tai–Chung Tseng et al.   GASTROENTEROLOGY

Serum and glucocorticoid kinase 3 at 8q13.1 promotes cell proliferation and survival in hepatocellular carcinoma

(2012) Ming Liu et al.   HEPATOLOGY

Acute promyelocytic leukemia, arsenic, and PML bodies

(2012) Hugues de Thé et al.   JOURNAL OF CELL BIOLOGY

DNA viruses and the cellular DNA-damage response

(2012) A. S. Turnell et al.   JOURNAL OF GENERAL VIROLOGY

HBsAg Inhibits the Translocation of JTB into Mitochondria in HepG2 Cells and Potentially Plays a Role in HCC Progression

(2012) Yun-Peng Liu et al.   PLoS One

Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans

(2012) X. Geng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A clustered ground-glass hepatocyte pattern represents a new prognostic marker for the recurrence of hepatocellular carcinoma after surgery

(2011) Hung-Wen Tsai et al.   CANCER

The relative contribution of pro-apoptotic p53-target genes in the triggering of apoptosis following DNA damage in vitro and in vivo

(2011) Kageaki Kuribayashi et al.   CELL CYCLE

DNA Repair: From Genome Maintenance to Biomarker and Therapeutic Target

(2011) S. Jalal et al.   CLINICAL CANCER RESEARCH

The Unfolded Protein Response (UPR)-activated Transcription Factor X-box-binding Protein 1 (XBP1) Induces MicroRNA-346 Expression That Targets the Human Antigen Peptide Transporter 1 (TAP1) mRNA and Governs Immune Regulatory Genes

(2011) Rafal Bartoszewski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Promyelocytic Leukemia Protein in Host Antiviral Defense

(2011) Marie-Claude Geoffroy et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Functional Connection between Rad51 and PML in Homology-Directed Repair

(2011) Sergei Boichuk et al.   PLoS One

Transgenic Expression of Entire Hepatitis B Virus in Mice Induces Hepatocarcinogenesis Independent of Chronic Liver Injury

(2011) Bing Na et al.   PLoS One

DNA double-strand break repair pathways, chromosomal rearrangements and cancer

(2011) Torben R. Kasparek et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Reactivation of hepatitis B

(2010) Jay H. Hoofnagle   HEPATOLOGY

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Viral hepatocarcinogenesis

(2010) W-L Tsai et al.   ONCOGENE

PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium Release

(2010) C. Giorgi et al.   SCIENCE

Poly(ADP-Ribose) Polymerase Inhibition as a Model for Synthetic Lethality in Developing Radiation Oncology Targets

(2010) Anthony J. Chalmers et al.   SEMINARS IN RADIATION ONCOLOGY

PML Nuclear Bodies

(2010) V. Lallemand-Breitenbach et al.   Cold Spring Harbor Perspectives in Biology

IFN- -Induced Apoptosis in Hepatocellular Carcinoma Involves Promyelocytic Leukemia Protein and TRAIL Independently of p53

(2009) K. Herzer et al.   CANCER RESEARCH

Perspectives in PML: a unifying framework for PML function

(2009) Katherine et al.   Frontiers in Bioscience-Landmark

Promyelocytic Leukemia Nuclear Bodies Link the DNA Damage Repair Pathway with Hepatitis B Virus Replication: Implications for Hepatitis B Virus Exacerbation during Chemotherapy and Radiotherapy

(2009) Y.-L. Chung et al.   MOLECULAR CANCER RESEARCH

Formation of Dynamic γ-H2AX Domains along Broken DNA Strands Is Distinctly Regulated by ATM and MDC1 and Dependent upon H2AX Densities in Chromatin

(2009) Velibor Savic et al.   MOLECULAR CELL

Synthetic Lethality — A New Direction in Cancer-Drug Development

(2009) J. Dirk Iglehart et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interplay between Herpesvirus Infection and Host Defense by PML Nuclear Bodies

(2009) Nina Tavalai et al.   Viruses-Basel

Hepatitis B virus core protein inhibits TRAIL-induced apoptosis of hepatocytes by blocking DR5 expression

(2008) J Du et al.   CELL DEATH AND DIFFERENTIATION

A Synthetic Lethal Therapeutic Approach: Poly(ADP) Ribose Polymerase Inhibitors for the Treatment of Cancers Deficient in DNA Double-Strand Break Repair

(2008) Alan Ashworth   JOURNAL OF CLINICAL ONCOLOGY