Dysfunction of dopamine homeostasis: clues in the hunt for novel Parkinson's disease therapies

Parkinsonism Due to Mutations in PINK1, Parkin, and DJ-1 and Oxidative Stress and Mitochondrial Pathways

(2013) M. R. Cookson   Cold Spring Harbor Perspectives in Medicine

Therapies in Parkinsonʼs disease

(2012) Joseph Jankovic et al.   CURRENT OPINION IN NEUROLOGY

Dopamine-derived Quinones Affect the Structure of the Redox Sensor DJ-1 through Modifications at Cys-106 and Cys-53

(2012) Stefania Girotto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurodegeneration and Motor Dysfunction in Mice Lacking Cytosolic and Mitochondrial Aldehyde Dehydrogenases: Implications for Parkinson's Disease

(2012) Margaret Chia-Ying Wey et al.   PLoS One

Human SOD2 Modification by Dopamine Quinones Affects Enzymatic Activity by Promoting Its Aggregation: Possible Implications for Parkinson’s Disease

(2012) Elisa Belluzzi et al.   PLoS One

Functional significance of aldehyde dehydrogenase ALDH1A1 to the nigrostriatal dopamine system

(2011) David W. Anderson et al.   BRAIN RESEARCH

Dopamine-derived biological reactive intermediates and protein modifications: Implications for Parkinson's disease

(2011) Yunden Jinsmaa et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Molecular Mechanisms of PINK1-Related Neurodegeneration

(2011) Joe H. Pogson et al.   Current Neurology and Neuroscience Reports

Tetrabenazine for the treatment of chorea and other hyperkinetic movement disorders

(2011) Joseph Jankovic et al.   Expert Review of Neurotherapeutics

How Addictive Drugs Disrupt Presynaptic Dopamine Neurotransmission

(2011) David Sulzer   NEURON

MAO-inhibitors in Parkinson's Disease

(2011) Peter Riederer et al.   Experimental Neurobiology

Dopamine quinones interact with α-synuclein to form unstructured adducts

(2010) Marco Bisaglia et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gene Therapy in Parkinsonʼs Disease

(2010) Li Rebekah Feng et al.   CNS DRUGS

Catechols in post-mortem brain of patients with Parkinson disease

(2010) D. S. Goldstein et al.   EUROPEAN JOURNAL OF NEUROLOGY

A rare novel deletion of the tyrosine hydroxylase gene in Parkinson disease

(2010) Güney Bademci et al.   HUMAN MUTATION

Dopamine Transporter Genetic Variants and Pesticides in Parkinson’s Disease

(2009) Beate R. Ritz et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Dopamine transporter glycosylation correlates with the vulnerability of midbrain dopaminergic cells in Parkinson's disease

(2009) Domingo Afonso-Oramas et al.   NEUROBIOLOGY OF DISEASE

New considerations in the medical management of early Parkinson's disease: Impact of recent clinical trials on treatment strategy

(2009) Robert A. Hauser   PARKINSONISM & RELATED DISORDERS

Dopamine Gene Therapy for Parkinson's Disease in a Nonhuman Primate Without Associated Dyskinesia

(2009) B. Jarraya et al.   Science Translational Medicine

Direct Binding of GTP Cyclohydrolase and Tyrosine Hydroxylase

(2008) Kevin M. Bowling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered vesicular dopamine storage in Parkinson's disease: a premature demise

(2008) W. Michael Caudle et al.   TRENDS IN NEUROSCIENCES

Viral vectors for in vivo gene transfer in Parkinson's disease: Properties and clinical grade production

(2007) Ronald J. Mandel et al.   EXPERIMENTAL NEUROLOGY