Channel sialic acids limit hERG channel activity during the ventricular action potential

Drug-induced hERG Block and Long QT Syndrome

(2010) Harry J. Witchel   Cardiovascular Therapeutics

Role of hERG potassium channel assays in drug development

(2010) Birgit Priest et al.   Channels

The corrected QT interval in 24 h ECGs in neonates

(2010) Thomas Krasemann et al.   Clinical Research in Cardiology

Sialic Acids Attached toO-Glycans Modulate Voltage-gated Potassium Channel Gating

(2010) Tara A. Schwetz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A KCR1 variant implicated in susceptibility to the long QT syndrome

(2010) Kenshi Hayashi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A novel mutation and first report of dilated cardiomyopathy in ALG6-CDG (CDG-Ic): a case report

(2010) Mohammed Al-Owain et al.   Orphanet Journal of Rare Diseases

An evaluation of hERG current assay performance: Translating preclinical safety studies to clinical QT prolongation

(2010) Gary Gintant   PHARMACOLOGY & THERAPEUTICS

N-glycans modulate Kv1.5 gating but have no effect on Kv1.4 gating

(2009) Tara A. Schwetz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Levofloxacin can be used effectively as a positive control in thorough QT/QTc studies in healthy volunteers

(2009) Jorg Taubel et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Cardiomyopathy in the congenital disorders of glycosylation (CDG): a case of late presentation and literature review

(2009) E. J. Footitt et al.   JOURNAL OF INHERITED METABOLIC DISEASE

H1 antihistamine drug promethazine directly blocks hERG K+ channel

(2009) Su-Hyun Jo et al.   PHARMACOLOGICAL RESEARCH

Regulated and aberrant glycosylation modulate cardiac electrical signaling

(2009) M. L. Montpetit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Kv1.2 potassium channel: The position of an N-glycan on the extracellular linkers affects its protein expression and function

(2008) Jing Zhu et al.   BRAIN RESEARCH

Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

(2008) Hugo M. Vargas et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS