ATP released from cardiac fibroblasts via connexin hemichannels activates profibrotic P2Y2 receptors

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Uridine triphosphate (UTP) induces profibrotic responses in cardiac fibroblasts by activation of P2Y2 receptors

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Both sides now: multiple interactions of ATP with pannexin-1 hemichannels. Focus on “A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP”

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Pannexins, distant relatives of the connexin family with specific cellular functions?

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Emerging concepts in cardiac matrix biologyThis article is one of a selection of papers published in a special issue on Advances in Cardiovascular Research.

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Cardiac Fibroblast

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ATP release by way of connexin 36 hemichannels mediates ischemic tolerance in vitro

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P2Y6 receptor-Gα12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis

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ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear

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