Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease

Does Impairment of the Ubiquitin-Proteasome System or the Autophagy-Lysosome Pathway Predispose Individuals to Neurodegenerative Disorders such as Parkinson's Disease?

(2017) Noriyuki Matsuda et al.   JOURNAL OF ALZHEIMERS DISEASE

CSF α-Synuclein Does Not Discriminate Dementia with Lewy Bodies from Alzheimer's Disease

(2017) Fransje E. Reesink et al.   JOURNAL OF ALZHEIMERS DISEASE

DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease

(2010) Zhen Hong et al.   BRAIN

Phosphorylated α-Synuclein at Ser-129 Is Targeted to the Proteasome Pathway in a Ubiquitin-independent Manner

(2010) Youhei Machiya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-Produced  -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

(2010) E. Emmanouilidou et al.   JOURNAL OF NEUROSCIENCE

Imaging Approaches to Parkinson Disease

(2010) D. J. Brooks   JOURNAL OF NUCLEAR MEDICINE

Clinical implications of gene discovery in Parkinson's disease and parkinsonism

(2010) Christian Wider et al.   MOVEMENT DISORDERS

Plasma α-synuclein in patients with Parkinson's disease with and without treatment

(2010) Raquel Duran et al.   MOVEMENT DISORDERS

Progress towards a molecular biomarker for Parkinson disease

(2010) Penelope Foulds et al.   Nature Reviews Neurology

Detection of elevated levels of  -synuclein oligomers in CSF from patients with Parkinson disease

(2010) T. Tokuda et al.   NEUROLOGY

Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease

(2010) Min Shi et al.   NEUROSCIENCE LETTERS

Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications

(2009) Hong Qing et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biological fluid biomarkers in neurodegenerative parkinsonism

(2009) Michael Eller et al.   Nature Reviews Neurology

Dissecting the potential molecular mechanisms underlying α-synuclein cell-to-cell transfer in Parkinson's disease

(2009) Elodie Angot et al.   PARKINSONISM & RELATED DISORDERS

Applicability of current staging/categorization of α-synuclein pathology and their clinical relevance

(2008) Laura Parkkinen et al.   ACTA NEUROPATHOLOGICA

Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

(2008) Brit Mollenhauer et al.   EXPERIMENTAL NEUROLOGY

Phosphorylation at Ser-129 but Not the Phosphomimics S129E/D Inhibits the Fibrillation of α-Synuclein

(2008) Katerina E. Paleologou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2008) G Irvine et al.   MOLECULAR MEDICINE

Red Blood Cells Are the Major Source of Alpha-Synuclein in Blood

(2008) Robin Barbour et al.   Neurodegenerative Diseases

The phosphorylation state of Ser-129 in human  -synuclein determines neurodegeneration in a rat model of Parkinson disease

(2008) O. S. Gorbatyuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA