Dietary and genetic evidence for enhancing glucose metabolism and reducing obesity by inhibiting klotho functions

Osteo-renal regulation of systemic phosphate metabolism

(2011) Mohammed Shawkat Razzaque   IUBMB LIFE

Phosphate toxicity: new insights into an old problem

(2010) M. Shawkat Razzaque   CLINICAL SCIENCE

Development of high-fat-diet-induced obesity in female metallothionein-null mice

(2010) Masao Sato et al.   FASEB JOURNAL

TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet

(2010) Federica Cioffi et al.   FASEB JOURNAL

Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism

(2010) Sylvie Rabot et al.   FASEB JOURNAL

Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity

(2010) Damir Zadravec et al.   FASEB JOURNAL

Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging

(2010) Mutsuko Ohnishi et al.   FASEB JOURNAL

Body Mass Index and Survival in Men and Women Aged 70 to 75

(2010) Leon Flicker et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

The dualistic role of vitamin D in vascular calcifications

(2010) M. Shawkat Razzaque   KIDNEY INTERNATIONAL

In Vivo Genetic Evidence for Suppressing Vascular and Soft-Tissue Calcification Through the Reduction of Serum Phosphate Levels, Even in the Presence of High Serum Calcium and 1,25-Dihydroxyvitamin D Levels

(2009) Mutsuko Ohnishi et al.   Circulation-Cardiovascular Genetics

Diet-induced obesity in female mice leads to peroxidized lipid accumulations and impairment of hippocampal neurogenesis during the early life of their offspring

(2009) Yusuke Tozuka et al.   FASEB JOURNAL

Inactivation of klotho function induces hyperphosphatemia even in presence of high serum fibroblast growth factor 23 levels in a genetically engineered hypophosphatemic (Hyp) mouse model

(2009) Teruyo Nakatani et al.   FASEB JOURNAL

Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1α-hydroxylase

(2009) Mutsuko Ohnishi et al.   KIDNEY INTERNATIONAL

Regulation of Renal Outer Medullary Potassium Channel and Renal K+ Excretion by Klotho

(2009) S.-K. Cha et al.   MOLECULAR PHARMACOLOGY

The FGF23–Klotho axis: endocrine regulation of phosphate homeostasis

(2009) M. Shawkat Razzaque   Nature Reviews Endocrinology

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis

(2008) Teruyo Nakatani et al.   FASEB JOURNAL

Klotho is a target gene of PPAR-γ

(2008) Hong Zhang et al.   KIDNEY INTERNATIONAL