Site-specific recombinases: from tag-and-target- to tag-and-exchange-based genomic modifications

Therapeutic Applications of the PhiC31 Integrase System

(2012) Christopher L. Chavez et al.   CURRENT GENE THERAPY

Intermediates in serine recombinase-mediated site-specific recombination

(2011) W. Marshall Stark et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Rapid derivation of genetically related mutants from embryonic cells harboring a recombinase-specificTrp53platform

(2011) Quan-Xiang Wei et al.   CELL CYCLE

Preliminary study on the DNA-binding properties of phage ΦC31 integrase

(2011) Zhihui Li et al.   GENE

Long-term phenotypic correction in factor IX knockout mice by using phiC31 integrase-mediated gene therapy

(2011) A Keravala et al.   GENE THERAPY

Recombinase-Mediated Cassette Exchange (RMCE): Traditional Concepts and Current Challenges

(2011) Soeren Turan et al.   JOURNAL OF MOLECULAR BIOLOGY

High throughput gene trapping and postinsertional modifications of gene trap alleles

(2011) Frank Schnütgen et al.   METHODS

Arm site independence of coliphage HK022 integrase in human cells

(2011) Natalia Malchin et al.   MOLECULAR GENETICS AND GENOMICS

A phage protein that binds φC31 integrase to switch its directionality

(2011) Thanafez Khaleel et al.   MOLECULAR MICROBIOLOGY

Resources for proteomics in mouse embryonic stem cells

(2011) Frank Schnütgen et al.   NATURE METHODS

High-level transgene expression by homologous recombination-mediated gene transfer

(2011) Mélanie Grandjean et al.   NUCLEIC ACIDS RESEARCH

VCre/VloxP and SCre/SloxP: new site-specific recombination systems for genome engineering

(2011) Emiko Suzuki et al.   NUCLEIC ACIDS RESEARCH

Zinc is essential for high-affinity DNA binding and recombinase activity of φC31 integrase

(2011) Andrew R. McEwan et al.   NUCLEIC ACIDS RESEARCH

Efficient recombinase-mediated cassette exchange at the AAVS1 locus in human embryonic stem cells using baculoviral vectors

(2011) Chrishan J. A. Ramachandra et al.   NUCLEIC ACIDS RESEARCH

Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery

(2011) Melanie Galla et al.   NUCLEIC ACIDS RESEARCH

A Genome-Wide Analysis of FRT-Like Sequences in the Human Genome

(2011) Jeffry L. Shultz et al.   PLoS One

Non-Integrative Lentivirus Drives High-Frequency cre-Mediated Cassette Exchange in Human Cells

(2011) Raul Torres et al.   PLoS One

A Comparison of Exogenous Promoter Activity at the ROSA26 Locus Using a PhiC31 Integrase Mediated Cassette Exchange Approach in Mouse ES Cells

(2011) Chiann-mun Chen et al.   PLoS One

Site-specific integrase-mediated transgenesis in mice via pronuclear injection

(2011) B. Tasic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gammaretroviral Vectors: Biology, Technology and Application

(2011) Tobias Maetzig et al.   Viruses-Basel

Site-specific recombination by φC31 integrase and other large serine recombinases

(2010) Margaret C.M. Smith et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Production of Non Viral DNA Vectors

(2010) Martin Schleef et al.   CURRENT GENE THERAPY

Refinement of Tools for Targeted Gene Expression in Drosophila

(2010) B. D. Pfeiffer et al.   GENETICS

TK.007: A Novel, Codon-Optimized HSVtk(A168H) Mutant for Suicide Gene Therapy

(2010) Ellen Preuß et al.   HUMAN GENE THERAPY

Multiplexing RMCE: Versatile Extensions of the Flp-Recombinase-Mediated Cassette-Exchange Technology

(2010) Soeren Turan et al.   JOURNAL OF MOLECULAR BIOLOGY

High Efficiency of a Sequential Recombinase-Mediated Cassette Exchange Reaction in Escherichia coli

(2010) Natalia Malchin et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

PhiC31 integrase facilitates genetic approaches combining multiple recombinases

(2010) Claudio Monetti et al.   METHODS

Gene Correction by Homologous Recombination With Zinc Finger Nucleases in Primary Cells From a Mouse Model of a Generic Recessive Genetic Disease

(2010) Jon P Connelly et al.   MOLECULAR THERAPY

Dual RMCE for efficient re-engineering of mouse mutant alleles

(2010) Marco Osterwalder et al.   NATURE METHODS

Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps

(2010) Laura Schebelle et al.   NUCLEIC ACIDS RESEARCH

Pronuclear injection-based mouse targeted transgenesis for reproducible and highly efficient transgene expression

(2010) Masato Ohtsuka et al.   NUCLEIC ACIDS RESEARCH

Protein transduction from retroviral Gag precursors

(2010) Christine Voelkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Cleavage is Independent of Synapsis during Streptomyces Phage φBT1 Integrase-Mediated Site-Specific Recombination

(2010) Lin Zhang et al.   Journal of Molecular Cell Biology

Cytoplasmic injection of circular plasmids allows targeted expression in mammalian embryos

(2009) Khursheed Iqbal et al.   BIOTECHNIQUES

Effect of nuclear localization and hydrodynamic delivery-induced cell division on φC31 integrase activity

(2009) L E Woodard et al.   GENE THERAPY

Novel Tag-and-Exchange (RMCE) Strategies Generate Master Cell Clones with Predictable and Stable Transgene Expression Properties

(2009) Junhua Qiao et al.   JOURNAL OF MOLECULAR BIOLOGY

Minicircle Performance Depending on S/MAR–Nuclear Matrix Interactions

(2009) Sandra Broll et al.   JOURNAL OF MOLECULAR BIOLOGY

DNA binding and synapsis by the large C-terminal domain of  C31 integrase

(2009) A. R. McEwan et al.   NUCLEIC ACIDS RESEARCH

Synthesis of programmable integrases

(2009) R. M. Gordley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly Efficient In Vitro Site-Specific Recombination System Based on Streptomyces Phage  BT1 Integrase

(2008) L. Zhang et al.   JOURNAL OF BACTERIOLOGY

Cellular Restriction of Retrovirus Particle-Mediated mRNA Transfer

(2008) M. Galla et al.   JOURNAL OF VIROLOGY

In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette

(2008) E. Sangiorgi et al.   NUCLEIC ACIDS RESEARCH