Destabilization of the neuromuscular junction by proteolytic cleavage of agrin results in precocious sarcopenia

Accumulation of severely atrophic myofibers marks the acceleration of sarcopenia in slow and fast twitch muscles

(2011) Sharon L. Rowan et al.   EXPERIMENTAL GERONTOLOGY

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

(2010) Martin Picard et al.   AGING CELL

Remodeling of the neuromuscular junction precedes sarcopenia related alterations in myofibers

(2010) Michael R. Deschenes et al.   EXPERIMENTAL GERONTOLOGY

Slow twitch soleus muscle is not protected from sarcopenia in senescent rats

(2010) E.E. Carter et al.   EXPERIMENTAL GERONTOLOGY

Specific proteolytic cleavage of agrin regulates maturation of the neuromuscular junction

(2010) M. F. Bolliger et al.   JOURNAL OF CELL SCIENCE

Neurotrypsin cleaves agrin locally at the synapse

(2008) Alexander Stephan et al.   FASEB JOURNAL

Age-related reductions in the estimated numbers of motor units are minimal in the human soleus

(2008) Brian H. Dalton et al.   MUSCLE & NERVE