New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells

Novel Agents on the Horizon for Cancer Therapy

(2009) W. W. Ma et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Kinome Profiling in Pediatric Brain Tumors as a New Approach for Target Discovery

(2009) A. H. Sikkema et al.   CANCER RESEARCH

Combined Radio- and Chemotherapy of Brain Tumours in Adult Patients

(2009) C. Nieder et al.   CLINICAL ONCOLOGY

The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cells

(2009) Alessandra Rossi et al.   INTERNATIONAL JOURNAL OF CANCER

The decision to enter mitosis: feedback and redundancy in the mitotic entry network

(2009) Arne Lindqvist et al.   JOURNAL OF CELL BIOLOGY

Improving the prognosis for patients with glioblastoma: the rationale for targeting Src

(2009) John de Groot et al.   JOURNAL OF NEURO-ONCOLOGY

Medulloblastoma in children under the age of three years: a retrospective Canadian review

(2009) Donna L. Johnston et al.   JOURNAL OF NEURO-ONCOLOGY

Analysis of apoptosis and expression of genes related to apoptosis in cultures of follicles derived from vitrified and non-vitrified ovaries

(2009) T. Mazoochi et al.   MOLECULAR HUMAN REPRODUCTION

Evidence that Resistance to Nilotinib May Be Due to BCR-ABL, Pgp, or Src Kinase Overexpression

(2008) F.-X. Mahon et al.   CANCER RESEARCH

Medulloblastoma: From Molecular Pathology to Therapy

(2008) A. Rossi et al.   CLINICAL CANCER RESEARCH

Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines

(2008) Silvia Schenone et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells

(2008) Adriano Spreafico et al.   FASEB JOURNAL

Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells

(2008) Chandramu Chetty et al.   INTERNATIONAL JOURNAL OF CANCER

Src Directly Phosphorylates Bif-1 and Prevents Its Interaction with Bax and the Initiation of Anoikis

(2008) Hirohito Yamaguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling pathways in medulloblastoma

(2008) Fadila Guessous et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy

(2008) Jinyan Du et al.   NATURE BIOTECHNOLOGY

Flexibility and charge asymmetry in the activation loop of Src tyrosine kinases

(2008) Nilesh K. Banavali et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS