Article
Multidisciplinary Sciences
Joseph Ochieng, Betty Kwagala, John Barugahare, Erisa Mwaka, Deborah Ekusai-Sebatta, Joseph Ali, Nelson K. Sewankambo
Summary: This study explores researchers' perspectives and experiences regarding feedback of incidental genomics findings to participants in genetics and genomics research. The study finds that researchers generally find it acceptable to share incidental research findings with participants, but face challenges such as lack of ethical guidelines and uncertainty about the findings.
Editorial Material
Peripheral Vascular Disease
Michael Stowasser
Summary: Additional digital content can be found in the text.
Article
Health Care Sciences & Services
Katherine Ann Gielissen, Emily Pinto Taylor, David Vermette, Benjamin Doolittle
Summary: This study identified factors contributing to career satisfaction and life satisfaction among primary care physicians through qualitative interviews. The findings revealed that intrinsic factors such as love for work and value-oriented beliefs, as well as extrinsic factors like fulfilling social networks, play critical roles in physician thriving. The study proposed a model for physician thriving based on the identified critical themes and discussed barriers and opportunities for wider application in the physician community.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2021)
Review
Health Care Sciences & Services
Luisa Silva, Nadeem Qureshi, Hasidah Abdul-Hamid, Stephen Weng, Joe Kai, Jo Leonardi-Bee
Summary: There is currently insufficient evidence to determine the most effective method of systematically identifying FH in non-specialist settings.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Primary Health Care
Zhimin Poon, Esther Cui Wei Lee, Li Ping Ang, Ngiap Chuan Tan
Summary: The postpartum period is defined as 12 weeks following childbirth, during which PCPs often manage postpartum women in the community. The study aimed to explore PCPs' experiences in managing postpartum mothers, finding that personal attributes and knowledge influenced their care delivery.
BMC FAMILY PRACTICE
(2021)
Article
Biochemistry & Molecular Biology
Agnes Sebastian, June C. Carroll, Meredith Vanstone, Marc Clausen, Rita Kodida, Emma Reble, Chloe Mighton, Salma Shickh, Melyssa Aronson, Andrea Eisen, Christine Elser, Jordan Lerner-Ellis, Raymond H. Kim, Yvonne Bombard
Summary: Primary care providers (PCPs) often approach the management of secondary genomic findings (SFs) through the lens of actionability, actively searching for clinical relevance and considering a wide range of immediate and future actions. They see clinical actionability as the main benefit, mitigating potential harms such as patient anxiety and unnecessary investigations. Further research is needed to explore if the emphasis on actionability by PCPs may conflict with patients' expectations or lead to overutilization of healthcare resources.
EUROPEAN JOURNAL OF HUMAN GENETICS
(2022)
Article
Health Care Sciences & Services
Sophie Beland, Mireille Lambert, Alannah Delahunty-Pike, Dana Howse, Charlotte Schwarz, Maud-Christine Chouinard, Kris Aubrey-Bassler, Fred Burge, Shelley Doucet, Alya Danish, Olivier Dumont-Samson, Mathieu Bisson, Alison Luke, Marilyn Macdonald, Andre Gaudreau, Judy Porter, Donna Rubenstein, Veronique Sabourin, Cathy Scott, Mike Warren, Linda Wilhelm, Catherine Hudon
Summary: This study aimed to describe and compare the experiences of patient partners and academic researchers in patient engagement research. The findings highlight the importance of evolving relationships, creating an environment that fosters patient engagement, striking a balance, and recognizing the impact and value of patient engagement. The experiences of patient partners and academic researchers differed based on their backgrounds, motives, and expectations, but both groups emphasized the need for structure and flexibility in patient engagement.
HEALTH EXPECTATIONS
(2022)
Article
Genetics & Heredity
Devan M. Duenas, Kelly J. Shipman, Kathryn M. Porter, Elizabeth Shuster, Claudia Guerra, Ana Reyes, Tia L. Kauffman, Jessica Ezzell Hunter, Katrina A. B. Goddard, Benjamin S. Wilfond, Stephanie A. Kraft
Summary: This study investigated the motivations and concerns of primary care patients regarding participation in research. The findings showed that motivations included the desire to learn about future risk, help family, and advance research, while concerns included privacy, research burdens, and coping with genetic information.
GENETICS IN MEDICINE
(2022)
Article
Multidisciplinary Sciences
Maude Laberge, Francesca Katherine Brundisini, Herve Tchala Vignon Zomahoun, Jasmine Sawadogo, Jose Massougbodji, Amede Gogovor, Genevieve David, France Legare
Summary: This study explores how citizens, physicians, and communication specialists understand knowledge transfer in public spaces. Four kinds of knowledge were identified: biomedical, sociocultural beliefs, value-based reasoning, and institutional knowledge. The findings highlight the different perspectives on biomedical knowledge between physicians/communication specialists and citizens, which have implications for future knowledge exchange interventions with the public.
Article
Infectious Diseases
Ildiko Gagyor, Alastair D. Hay
Summary: Clinical and antimicrobial stewardship outcomes are crucial in pragmatic primary care trials, but currently lack agreed standards for design. Recommendations for future research designs include specifying interpretation of conflicting results, ensuring prescriptions from external sources are included in AMS effectiveness measures, prioritizing antimicrobial resistance in outcomes, considering antibiotics used in interventions as part of the outcome, and involving patients in establishing principles for prioritizing AMS or clinical outcomes.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2022)
Article
Oncology
Michael B. Wells, Sara Delilovic, Malin Gunnarsson, Jessica Dervish, Mia von Knorring, Henna Hasson
Summary: Primary care physicians in Sweden have recently implemented standardised care pathways (SCPs) for referring patients to specialists for cancer care diagnostics. While most PCPs see the value in SCPs for improving patient care and reducing wait times, there is a need for updated guidelines and clarification on SCP processes to optimize services for both patients and medical personnel.
EUROPEAN JOURNAL OF CANCER CARE
(2021)
Article
Biochemistry & Molecular Biology
Caitlin Slomp, Emily Morris, Morgan Price, Alison M. Elliott, Jehannine Austin
Summary: This study qualitatively explored the process of integrating genetic counsellors (GCs) into a multidisciplinary primary care setting. The study found that the integration process involves stages of disinterest or resistance, pre-collaboration, initial collaboration, and effective collaboration/integration of the GC into the team. Each stage has specific needs and barriers that need to be addressed.
EUROPEAN JOURNAL OF HUMAN GENETICS
(2022)
Article
Health Care Sciences & Services
Omar H. Ordaz, Raina L. Croff, LaTroy D. Robinson, Steven A. Shea, Nicole P. Bowles
Summary: Contrary to previous reports, Black American patients in this study generally accepted patient portals as tools for personalized care and reducing unfair disease burden in primary care. Increased communication, experience, and adoption of remote health care practices among Black Americans will lead to better health care opportunities.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Genetics & Heredity
June C. Carroll, Clare Liddy, Amir Afkham, Erin Keely, Elaine S. Goh, Gail E. Graham, Joanne A. Permaul, Judith Allanson, Ruth Heisey, Tutsirai Makuwaza, Donna P. Manca, Mary Ann O'Brien, Eva Grunfeld
Summary: The study aimed to investigate the effectiveness of electronic consultation (eConsult) in improving genetics service delivery in primary care. The results showed that eConsult provided timely genetics advice, helped avoid unnecessary patient referrals, and was perceived as valuable for patient management. However, for greater impact on access and wait times, systematic integration of eConsult into primary care providers and geneticists' practice is needed.
GENETICS IN MEDICINE
(2022)
Article
Multidisciplinary Sciences
Debbie Vermond, Esther de Groot, Valerie A. Sills, Georgios Lyratzopoulos, Fiona M. Walter, Niek J. de Wit, Greg Rubin
Summary: This study examines the evolution and co-evolution of academic social networks and collaborative research networks, finding that academic social networks are stable and encouraging for junior researchers, but may differ for male and female researchers. Moreover, the study demonstrates the benefits of creating academic social relationships for stimulating effective research collaboration.
Article
Public, Environmental & Occupational Health
Kelly Holloway, Fiona A. Miller
Summary: This article investigates the regulatory regime for molecular diagnostics in the US, highlighting the key role of private consultants in coverage and reimbursement. The study emphasizes the production of evidence as a critical part of the process and argues that consultants act as regulatory intermediaries, benefiting their clients' financial interests. The article suggests that public policy discussions should reconsider whose interests are represented in the regulatory regime.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Pediatrics
Celine Cressman, Fiona A. Miller, Astrid Guttmann, John Cairney, Robin Z. Hayeems
Summary: Joined-up governance (JUG) approaches have gained attention as mechanisms for tackling wicked policy problems, particularly in intersectoral areas such as child health. Investments in early childhood development, such as developmental screening, illustrate the challenges of JUG for child health.
Article
Business
Pascale Lehoux, Hudson P. Silva, Jean-Louis Denis, Fiona A. Miller, Renata Pozelli Sabio, Marguerite Mendell
Summary: This study aims to explore the challenges that Responsible Research and Innovation (RRI) poses to business models and value creation. Through multiple case studies, it was found that organizations face business model challenges from micro-, meso-, and macro-levels when trying to achieve responsible innovation, which affects the implementation of their business models and their capacity for responsible value creation.
JOURNAL OF PRODUCT INNOVATION MANAGEMENT
(2021)
Article
Ethics
Kelly Holloway, Nicole Simms, Robin Z. Hayeems, Fiona A. Miller
Summary: This study analyzes the marketing of noninvasive prenatal testing (NIPT) and identifies concerns regarding bias, misrepresentation, and lack of regulatory oversight. The findings highlight the potential for commercial imperatives to exacerbate issues in marketing materials.
HASTINGS CENTER REPORT
(2022)
Article
Health Care Sciences & Services
Jeff Myers, Ginah L. Kim, Jessica Bytautas, Fiona Webster
Summary: This study used critical discourse analysis to examine GOCDs documented by Canadian physicians in palliative medicine, critical care medicine, and general internal medicine. The study found differing conceptualizations of the GOCD, with goals being oriented towards either the person or the treatment.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2022)
Review
Public, Environmental & Occupational Health
M. Richardson, A. Erman, N. Daneman, F. A. Miller, B. Sander
Summary: This study assessed how the scope of the decision problem is defined in economic evaluations of interventions for Clostridioides difficile infection. Most studies focused on a single intervention, while only a few considered the relationship between multiple interventions. This has important implications for optimal allocation of healthcare resources.
JOURNAL OF HOSPITAL INFECTION
(2022)
Article
Genetics & Heredity
June C. Carroll, Clare Liddy, Amir Afkham, Erin Keely, Elaine S. Goh, Gail E. Graham, Joanne A. Permaul, Judith Allanson, Ruth Heisey, Tutsirai Makuwaza, Donna P. Manca, Mary Ann O'Brien, Eva Grunfeld
Summary: The study aimed to investigate the effectiveness of electronic consultation (eConsult) in improving genetics service delivery in primary care. The results showed that eConsult provided timely genetics advice, helped avoid unnecessary patient referrals, and was perceived as valuable for patient management. However, for greater impact on access and wait times, systematic integration of eConsult into primary care providers and geneticists' practice is needed.
GENETICS IN MEDICINE
(2022)
Editorial Material
Public, Environmental & Occupational Health
Stuart Hogarth, Fiona A. Miller, Steve Sturdy
SOCIAL SCIENCE & MEDICINE
(2022)
Review
Health Care Sciences & Services
Han Yan, Jessica Bytautas, Sarina Roslyn Isenberg, Ari Kaplan, Narges Hashemi, Mona Kornberg, Tekla Hendrickson
Summary: This study reviewed the literature on the grief and bereavement of family and friends following medical assistance in dying (MAiD), and identified several factors that impact their experience. The findings suggest that support is needed to address the complex and changing emotions of family and friends before, during, and after a MAiD death. Additionally, normalizing MAiD in society and reducing secrecy and stigma are necessary to improve the accessibility of resources for family and friends.
BMJ SUPPORTIVE & PALLIATIVE CARE
(2022)
Article
Health Policy & Services
Hassane Alami, Pascale Lehoux, Fiona A. A. Miller, Sara E. E. Shaw, Jean-Paul Fortin
Summary: Health systems have a responsibility to protect the health and well-being of individuals and populations, but healthcare contributes to a significant percentage of global greenhouse gas emissions. This paper examines the potential integration of "environmental sustainability" into the concept of the "Sextuple Aim" and explores the challenges and opportunities of incorporating environmental sustainability into healthcare goals. The authors propose policy and practical approaches to help healthcare systems move towards achieving the Sextuple Aim.
INTERNATIONAL JOURNAL OF HEALTH PLANNING AND MANAGEMENT
(2023)
Article
Health Care Sciences & Services
Lena Saleh, Gillian Parker, Michael Stevenson, Fiona A. Miller
BMC HEALTH SERVICES RESEARCH
(2023)
Review
Multidisciplinary Sciences
Gillian Z. Parker, Sarah Hunter, Samer A. Ghazi, Robin Z. Hayeems, Francois Rousseau, Fiona A. Miller
Summary: Decision impact studies in genomic medicine have become increasingly prevalent in cancer care. These studies aim to evaluate the impact of genomic tests on treatment decisions and provide evidence of clinical utility. This scoping review identified and characterized 87 studies reporting on different types of clinical utility outcomes.
Article
Multidisciplinary Sciences
Gillian A. Parker, Sarah Hunter, Stuart Hogarth, Fiona Miller
Summary: This study analyzes the importance of decision impact studies in genomic medicine, particularly in cancer research. The findings suggest that these studies are primarily conducted by collaborations between researchers and industry actors, aiming to provide evidence of clinical utility for proprietary genomic assays. The studies are funded by industry and the majority of authors have industry affiliations. The study emphasizes the need for further research into the impact of these studies on coverage and reimbursement decision-making.
Article
Health Policy & Services
Pascale Lehoux, Hudson Pacifico Silva, Fiona Miller, Jean-Louis Denis, Renata Sabio Pozelli
Summary: In order to promote equity and sustainability in health systems, Responsible Innovation in Health (RIH) calls for policy changes. However, current policies mainly focus on fostering the supply of innovations and neglect the health policies that affect their uptake. This study aims to inform policies that can support RIH by examining the experiences of RIH-oriented entrepreneurs with policies that influence both the supply and demand of their innovations.
INTERNATIONAL JOURNAL OF HEALTH PLANNING AND MANAGEMENT
(2023)
Article
Environmental Sciences
Owen Dan Luo, Yasmeen Razvi, Gurleen Kaur, Michelle Lim, Kelti Smith, Jacob Joel Kirsh Carson, Claudel Petrin-Desrosiers, Victoria Haldane, Nicole Simms, Fiona A. Miller
Summary: More and more healthcare professionals are recognizing the importance of delivering low-carbon sustainable health systems. This study explored how physicians can be motivated and supported in their pursuit of this goal. Through interviews with climate-engaged Canadian physicians, the study identified actions physicians can take to promote sustainable healthcare and the motivators and enablers of physician engagement in this area.
LANCET PLANETARY HEALTH
(2023)
