Article
Environmental Sciences
F. Mikaela Nordborg, Diane L. Brinkman, Andrew P. Negri
Summary: This study provides data on the sensitivity of different post-settlement life stages of the coral species Acropora millepora to heavy fuel oil (HFO) exposure. The results show that ultraviolet radiation (UVR) increases the toxicity of HFO towards corals, supporting the importance of incorporating UVR in oil toxicity testing.
ENVIRONMENTAL POLLUTION
(2022)
Article
Chemistry, Multidisciplinary
Guodong Gong, Shuang Gao, Zhuolin Xie, Xiaoyu Ye, Ying Lu, Huali Yang, Xiaojian Zhu, Run-Wei Li
Summary: This research demonstrates a visible light-triggered artificial nociceptor with a simple ITO/CeO2-x/Pt sandwich structure, successfully mimicking the pain-perceptual characteristics of the human visual system, and has significant potential for applications in next-generation intelligent and low-power perceptual systems.
Article
Biology
Tomoki Harada, Shoji Hata, Rioka Takagi, Takuma Komori, Masamitsu Fukuyama, Takumi Chinen, Daiju Kitagawa
Summary: This study analyzes the impact of phototoxicity on mitosis and identifies ascorbic acid as an efficient agent to alleviate these effects. The addition of ascorbic acid to the media allows for high temporal resolution imaging of mitotic events without photodamage.
COMMUNICATIONS BIOLOGY
(2023)
Article
Microbiology
Soichiro Fukuda, Shunsuke Ito, Jun Nishikawa, Tatsuya Takagi, Naoto Kubota, Ken-ichiro Otsuyama, Hidehiro Tsuneoka, Junzo Nojima, Koji Harada, Katsuaki Mishima, Yutaka Suehiro, Takahiro Yamasaki, Isao Sakaida
Summary: The study demonstrated that deep ultraviolet LED light therapy has a strong bactericidal effect on Fusobacterium nucleatum by causing DNA damage, indicating its potential in preventing colorectal cancer.
Article
Biochemistry & Molecular Biology
Zhe Cha, Zhiyuan Yin, A. Luodan, Lingling Ge, Junling Yang, Xiaona Huang, Hui Gao, Xia Chen, Zhou Feng, Lingyue Mo, Juncai He, Shuang Zhu, Maoru Zhao, Zui Tao, Zhanjun Gu, Haiwei Xu
Summary: This study established a MG lineage-tracing mouse model of light-induced retinal damage and found that Fullerol exhibited superior protection against light-induced retinal injury. Fullerol protected the retina by inhibiting gliosis through suppressing the TGF-beta pathway and enhancing the de-differentiation of MG cells. Transcription candidate pathways, including Nrf2 and Wnt10a pathways, were involved in Fullerol-induced neuroprotection.
Article
Endocrinology & Metabolism
Lu Yuan, Daohuan Kang, Weizhong Gu, Qing Chen, Zhen Meng, Yunyan Zheng, Bin Lu
Summary: Exposure to electrodeless lamp and LED lamp results in damage to the retinas of guinea pigs, leading to cell apoptosis and changes in protein levels.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Environmental Sciences
F. Mikaela Nordborg, Diane L. Brinkman, Gerard F. Ricardo, Susana Agusti, Andrew P. Negri
Summary: Different early life stages of Acropora millepora showed varying sensitivities to the dissolved fraction of heavy fuel oil, with larval metamorphosis being the most sensitive endpoint. Coexposure to UVR reduced toxicity thresholds across life stages and endpoints, emphasizing the importance of considering UVR when assessing oil toxicity in coral reefs.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biochemistry & Molecular Biology
Malgorzata B. Rozanowska, Barbara Czuba-Pelech, Bartosz Rozanowski
Summary: The study aimed to determine the optimal combinations of vitamins C, E, and zeaxanthin to prevent phototoxicity mediated by vitamin A aldehyde. Results showed that combining zeaxanthin with alpha-tocopherol provided substantial protection, enhancing cell viability significantly.
Article
Biology
Nagarajan Theruveethi, Bang Viet Bui, Manjunath B. Joshi, Manna Valiathan, Shonraj Ballae Ganeshrao, Sivakumar Gopalakrishnan, Shama Prasada Kabekkodu, Shailaja S. Bhat, Sudarshan Surendran
Summary: Blue light exposure can cause retinal damage and changes in visual cortex neurons, while blue light-blocking lenses can alleviate these damages.
Article
Biotechnology & Applied Microbiology
Sung-Won Kim, Gwang-Bum Im, Yeong Hwan Kim, Suk Ho Bhang
Summary: This study demonstrates the use of bOLED to enhance the paracrine secretion of hADSCs, resulting in improved therapeutic effects. The bOLED promotes angiogenesis through a cell-signaling mechanism and does not induce phototoxicity. This method effectively overcomes the barriers of toxicity and low yield in stem cell therapies.
BIOENGINEERING & TRANSLATIONAL MEDICINE
(2023)
Article
Cell Biology
Meenakshi Maurya, Tapas C. Nag, Pankaj Kumar, Tara Sankar Roy
Summary: This study investigates the impact of light exposure on the expression of iron-handling proteins in the chick retina. Results showed that intense light exposure led to an increase in retinal Fe2+ levels and lipid peroxidation, as well as changes in the expression patterns of various iron-handling proteins. These alterations may contribute to oxidative stress and retinal cell damage, highlighting the complex interplay between light exposure and iron metabolism in ocular health.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2021)
Review
Chemistry, Medicinal
Justyna Kowalska, Jakub Rok, Zuzanna Rzepka, Dorota Wrzesniok
Summary: Photosensitivity can be induced by drugs, with two types of reactions: photoallergy and phototoxicity. The risk of photosensitivity reactions increases with exposure to sunlight and the presence of photosensitizing substances in various products. Mechanisms of drug-induced photosensitivity are complex, involving oxidative stress, inflammation, and changes in melanin synthesis, leading to symptoms like erythema and swelling.
Article
Cell Biology
Sung-Won Kim, Yu-Jin Kim, Gwang-Bum Im, Yeoung Hwan Kim, Gun-Jae Jeong, Sung Min Cho, Haeshin Lee, Suk Ho Bhang
Summary: Low-level light therapy (LLLT) is a safe and noninvasive treatment method. Research has shown that using blue organic light-emitting diode (bOLED) can enhance the angiogenic properties of human adipose-derived stem cells (hADSC). This opens up new possibilities for the application of blue light in LLLT.
CELL BIOLOGY AND TOXICOLOGY
(2023)
Article
Biology
Tual Monfort, Salvatore Azzollini, Jeremy Brogard, Marilou Clemencon, Amelie Slembrouck-Brec, Valerie Forster, Serge Picaud, Olivier Goureau, Sacha Reichman, Olivier Thouvenin, Kate Grieve
Summary: Dynamic full-field optical coherence tomography (D-FFOCT) is a label-free imaging tool that can distinguish cell types and organelles in 3D live samples and monitor their activity. In this study, a D-FFOCT module design is presented that can be coupled to a commercial microscope with a stage top incubator, allowing non-invasive longitudinal imaging over extended periods of time. The imaging of human induced pluripotent stem cell-derived retinal organoids and retinal explants demonstrates the capability of D-FFOCT in capturing tissue and cell organization processes as well as individual structures. The optimized workflow for data acquisition, postprocessing, and saving significantly improves the efficiency compared to previous methods. Additionally, a method to increase the signal-to-noise ratio of D-FFOCT is demonstrated, enabling rapid screening of organoids.
COMMUNICATIONS BIOLOGY
(2023)
Article
Cell Biology
Natalia Ziolkowska, Bogdan Lewczuk, Natalia Szyrynska, Aleksandra Rawicka, Alla Vyniarska
Summary: This study examined the impact of low-intensity blue light on the albino Wistar rat retina, specifically the intrinsically photosensitive retinal ganglion cells (ipRGCs). Different exposure patterns of blue light were tested, and the results showed that prolonged exposure to low-intensity blue light caused damage to the retinas of the rats. This damage included decreased dendrite length, reduced immunoreactivity, changes in dendritic arborization, increased GFAP immunoreactivity, and apoptosis.