Current concepts on primary open-angle glaucoma genetics: a contribution to disease pathophysiology and future treatment

Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area

(2011) Chiea Chuen Khor et al.   HUMAN MOLECULAR GENETICS

Copy number variations on chromosome 12q14 in patients with normal tension glaucoma

(2011) John H. Fingert et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1

(2011) Kathryn P Burdon et al.   NATURE GENETICS

No Evidence of Association of Heterozygous NTF4 Mutations in Patients with Primary Open-Angle Glaucoma

(2010) Yutao Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Little evidence for association of the glaucoma gene MYOC with open-angle glaucoma

(2010) S. Sohn et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

The case for autoimmunity in glaucoma

(2010) Martin B. Wax   EXPERIMENTAL EYE RESEARCH

Collagen-related genes influence the glaucoma risk factor, central corneal thickness

(2010) Eranga N. Vithana et al.   HUMAN MOLECULAR GENETICS

Myocilin and optineurin coding variants in Hispanics of Mexican descent with POAG

(2010) Kristin K McDonald et al.   JOURNAL OF HUMAN GENETICS

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

(2010) Gudmar Thorleifsson et al.   NATURE GENETICS

Uncovering the roles of rare variants in common disease through whole-genome sequencing

(2010) Elizabeth T. Cirulli et al.   NATURE REVIEWS GENETICS

Genome-wide Association Study of Normal Tension Glaucoma: Common Variants in SRBD1 and ELOVL5 Contribute to Disease Susceptibility

(2010)   OPHTHALMOLOGY

SPARC Deficiency Results in Improved Surgical Survival in a Novel Mouse Model of Glaucoma Filtration Surgery

(2010) Li-Fong Seet et al.   PLoS One

Genetic Bases for Glaucoma

(2010) Nobuo Fuse   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Heterozygous NTF4 Mutations Impairing Neurotrophin-4 Signaling in Patients with Primary Open-Angle Glaucoma

(2009) Francesca Pasutto et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Differential Effects of Myocilin and Optineurin, Two Glaucoma Genes, on Neurite Outgrowth

(2009) Takahisa Koga et al.   AMERICAN JOURNAL OF PATHOLOGY

RNA interference as a gene silencing therapy for mutant MYOC protein in primary open angle glaucoma

(2009) Mao Li et al.   Diagnostic Pathology

Modulation of extracellular matrix turnover in the trabecular meshwork

(2009) Rudolf Fuchshofer et al.   EXPERIMENTAL EYE RESEARCH

Prevalence of myocilin gene mutations in a novel UK cohort of POAG patients

(2009) S Ennis et al.   EYE

Primary open angle glaucoma was not found to be associated with p53 codon 72 polymorphism in a Brazilian cohort

(2009) R.E. Silva et al.   GENETICS AND MOLECULAR RESEARCH

Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population

(2009) M. Nakano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matricellular proteins in the trabecular meshwork

(2008) Douglas J. Rhee et al.   EXPERIMENTAL EYE RESEARCH

The genetics of primary open-angle glaucoma: A review

(2008) R. Rand Allingham et al.   EXPERIMENTAL EYE RESEARCH

The Primary open-angle glaucoma gene WDR36 functions in ribosomal RNA processing and interacts with the p53 stress-response pathway

(2008) J. M. Skarie et al.   HUMAN MOLECULAR GENETICS

The Genome Gets Personal—Almost

(2008) W. Gregory Feero   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Role of CYP1B1 in Glaucoma

(2007) Vasilis Vasiliou et al.   Annual Review of Pharmacology and Toxicology

New links to the pathogenesis of Crohn disease provided by genome-wide association scans

(2007) Christopher G. Mathew   NATURE REVIEWS GENETICS