4.7 Article

Computational intelligence for microarray data and biomedical image analysis for the early diagnosis of breast cancer

Journal

EXPERT SYSTEMS WITH APPLICATIONS
Volume 39, Issue 16, Pages 12371-12377

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.eswa.2012.04.045

Keywords

Breast cancer; Microarray data; Image data; Computational intelligence; SMOTE; SMO

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The objective of this paper was to perform a comparative analysis of the computational intelligence algorithms to identify breast cancer in its early stages. Two types of data representations were considered: microarray based and medical imaging based. In contrast to previous researches, this research also considered the imbalanced nature of these data. It was observed that the SMO algorithm performed better for the majority of the test data, especially for microarray based data when accuracy was used as performance measure. Considering the imbalanced characteristic of the data, the Naive Bayes algorithm was seen to perform highly in terms of true positive rate (TPR). Regarding the influence of SMOTE, a well-known imbalanced data classification technique, it was observed that there was a notable performance improvement for J48, while the performance of SMO remained comparable for the majority of the datasets. Overall, the results indicated SMO as the most potential candidate for the microarray and image dataset considered in this research. (C) 2012 Elsevier Ltd. All rights reserved.

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