Role of chemokines in proteinuric kidney disorders

Targeting chemokines in proteinuria-induced renal disease

(2012) Juan Antonio Moreno et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms

(2012) Luigi Villa et al.   JOURNAL OF PATHOLOGY

TWEAK (tumor necrosis factor–like weak inducer of apoptosis) activates CXCL16 expression during renal tubulointerstitial inflammation

(2012) María Concepción Izquierdo et al.   KIDNEY INTERNATIONAL

Notice

(2012)   Kidney International Supplements

Antiproteinuric Effect of Chemokine C-C Motif Ligand 2 Inhibition in Subjects with Acute Proliferative Lupus Nephritis

(2011) Alessandro Ble et al.   AMERICAN JOURNAL OF NEPHROLOGY

Dual Blockade of the Homeostatic Chemokine CXCL12 and the Proinflammatory Chemokine CCL2 Has Additive Protective Effects on Diabetic Kidney Disease

(2011) Murthy N. Darisipudi et al.   AMERICAN JOURNAL OF PATHOLOGY

Discovery of INCB10820/PF-4178903, a potent, selective, and orally bioavailable dual CCR2 and CCR5 antagonist

(2011) Changsheng Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Correlations of Urinary Biomarkers, TNF-Like Weak Inducer of Apoptosis (TWEAK), Osteoprotegerin (OPG), Monocyte Chemoattractant Protein-1 (MCP-1), and IL-8 with Lupus Nephritis

(2011) Amal El-shehaby et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Discovery, Optimization, and Pharmacological Characterization of Novel Heteroaroylphenylureas Antagonists of C−C Chemokine Ligand 2 Function

(2011) Edgardo Laborde et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chemokines in Renal Injury

(2011) A. C. K. Chung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Gene expression of TWEAK/Fn14 and IP-10/CXCR3 in glomerulus and tubulointerstitium of patients with lupus nephritis

(2011) JIANXIN LU et al.   NEPHROLOGY

Oral supplementation of turmeric attenuates proteinuria, transforming growth factor-β and interleukin-8 levels in patients with overt type 2 diabetic nephropathy: A randomized, double-blind and placebo-controlled study

(2011) Parviz Khajehdehi et al.   SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY

Relationship between Oxidative Stress and Inflammatory Cytokines in Diabetic Nephropathy

(2010) Ahmed A. Elmarakby et al.   Cardiovascular Therapeutics

Anti-inflammatory effects of the GABAB receptor agonist baclofen in allergic contact dermatitis

(2010) Beatrice Duthey et al.   EXPERIMENTAL DERMATOLOGY

RANTES Deficiency Attenuates Autoantibody-Induced Glomerulonephritis

(2010) Chun Xie et al.   JOURNAL OF CLINICAL IMMUNOLOGY

A Fusion Protein Encoding the Second Extracellular Domain of CCR5 Arrests Chemokine-Induced Cosignaling and Effectively Suppresses Ongoing Experimental Autoimmune Encephalomyelitis

(2010) Y. Sapir et al.   JOURNAL OF IMMUNOLOGY

CCR6 Recruits Regulatory T Cells and Th17 Cells to the Kidney in Glomerulonephritis

(2010) J. E. Turner et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NF- B in Renal Inflammation

(2010) A. B. Sanz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CCR2 antagonism improves insulin resistance, lipid metabolism, and diabetic nephropathy in type 2 diabetic mice

(2010) Young Sun Kang et al.   KIDNEY INTERNATIONAL

Specificity tuning of antibody fragments to neutralize two human chemokines with a single agent

(2010) Séverine Fagète et al.   mAbs

Expression of the chemokine receptor CCR6 in human renal inflammation

(2010) D. Welsh-Bacic et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Urinary monocyte chemoattractant protein-1 excretion in children with glomerular proteinuria

(2010) Anna Wasilewska et al.   SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY

Efficient Renal Recruitment of Macrophages and T Cells in Mice Lacking the Duffy Antigen/Receptor for Chemokines

(2009) Volker Vielhauer et al.   AMERICAN JOURNAL OF PATHOLOGY

CXCL16 Is Expressed in Podocytes and Acts as a Scavenger Receptor for Oxidized Low-Density Lipoprotein

(2009) Paul Gutwein et al.   AMERICAN JOURNAL OF PATHOLOGY

Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes

(2009) S. G. Sayyed et al.   DIABETOLOGIA

Leukocyte - endothelial interactions in inflammation

(2009) Harald F. Langer et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CXCR4/CXCL12 Hyperexpression Plays a Pivotal Role in the Pathogenesis of Lupus

(2009) A. Wang et al.   JOURNAL OF IMMUNOLOGY

Rosiglitazone activation of PPARγ suppresses fractalkine signaling

(2009) Yihong Wan et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

CXCL10 and autoimmune diseases

(2008) Eun Young Lee et al.   AUTOIMMUNITY REVIEWS

Microarray Analysis of Glomerular Gene Expression in Murine Lupus Nephritis

(2008) Kae Teramoto et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Anti-Ccl2 Spiegelmer Permits 75% Dose Reduction of Cyclophosphamide to Control Diffuse Proliferative Lupus Nephritis and Pneumonitis in MRL-Fas(lpr) Mice

(2008) O. Kulkarni et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Immune Mediators in Idiopathic Nephrotic Syndrome: Evidence for a Relation Between Interleukin 8 and Proteinuria

(2008) Marcelo F O Souto et al.   PEDIATRIC RESEARCH