Role of toll-like receptors in systemic sclerosis

SNAPIN: an endogenous toll-like receptor ligand in rheumatoid arthritis

(2012) Bo Shi et al.   ANNALS OF THE RHEUMATIC DISEASES

Clinical and pathological significance of interleukin 6 overexpression in systemic sclerosis

(2012) Korsa Khan et al.   ANNALS OF THE RHEUMATIC DISEASES

New developments in Toll-like receptor targeted therapeutics

(2012) Dympna J Connolly et al.   CURRENT OPINION IN PHARMACOLOGY

Interleukin-6, its role in fibrosing conditions

(2012) Steven O’Reilly et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Cutting Edge: TLR13 Is a Receptor for Bacterial RNA

(2012) A. Hidmark et al.   JOURNAL OF IMMUNOLOGY

Gadolinium Compounds Signaling through TLR 4 and TLR 7 in Normal Human Macrophages: Establishment of a Proinflammatory Phenotype and Implications for the Pathogenesis of Nephrogenic Systemic Fibrosis

(2012) P. J. Wermuth et al.   JOURNAL OF IMMUNOLOGY

MyD88 mediated inflammatory signaling leads to CaMKII oxidation, cardiac hypertrophy and death after myocardial infarction

(2012) Madhu V. Singh et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Differential gene expression of MMP-1, TIMP-1 and HGF in clinically involved and uninvolved skin in South Africans with SSc

(2012) J. Frost et al.   RHEUMATOLOGY

T cells in systemic sclerosis: a reappraisal

(2012) S. O'Reilly et al.   RHEUMATOLOGY

A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators

(2011) J. C. A. Broen et al.   ARTHRITIS AND RHEUMATISM

Distinct evolution of TLR-mediated dendritic cell cytokine secretion in patients with limited and diffuse cutaneous systemic sclerosis

(2010) L. van Bon et al.   ANNALS OF THE RHEUMATIC DISEASES

Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists

(2010) D. Rajagopal et al.   BLOOD

Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNα/β and IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration

(2010) Robert Field et al.   BRAIN BEHAVIOR AND IMMUNITY

Ro60-Associated Single-Stranded RNA Links Inflammation with Fetal Cardiac Fibrosis via Ligation of TLRs: A Novel Pathway to Autoimmune-Associated Heart Block

(2010) Robert M. Clancy et al.   JOURNAL OF IMMUNOLOGY

Acute Serum Amyloid A Induces Migration, Angiogenesis, and Inflammation in Synovial Cells In Vitro and in a Human Rheumatoid Arthritis/SCID Mouse Chimera Model

(2010) M. Connolly et al.   JOURNAL OF IMMUNOLOGY

Poly(I:C) Drives Type I IFN- and TGFβ-Mediated Inflammation and Dermal Fibrosis Simulating Altered Gene Expression in Systemic Sclerosis

(2010) Giuseppina A. Farina et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype

(2010) Susan K Mathai et al.   LABORATORY INVESTIGATION

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

(2010) Anna-Barbara Stittrich et al.   NATURE IMMUNOLOGY

Rheumatoid arthritis progression mediated by activated synovial fibroblasts

(2010) Elena Neumann et al.   TRENDS IN MOLECULAR MEDICINE

Uric Acid Is a Danger Signal Activating NALP3 Inflammasome in Lung Injury Inflammation and Fibrosis

(2009) Pamela Gasse et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Autoantibody against one of the antioxidant repair enzymes, methionine sulfoxide reductase A, in systemic sclerosis: association with pulmonary fibrosis and vascular damage

(2009) Fumihide Ogawa et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Innate immunity and inflammation in systemic sclerosis

(2009) Robert Lafyatis et al.   CURRENT OPINION IN RHEUMATOLOGY

IL-1R1/MyD88 Signaling Is Critical for Elastase-Induced Lung Inflammation and Emphysema

(2009) I. Couillin et al.   JOURNAL OF IMMUNOLOGY

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease

(2009) Kim Midwood et al.   NATURE MEDICINE

Enhanced interleukin‐10 production by dendritic cells upon stimulation with Toll‐like receptor 4 agonists in systemic sclerosis that is possibly implicated in CCL18 secretion

(2009) A. W. T. van Lieshout et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

The role of Toll-like receptors in rheumatoid arthritis

(2009) Qi-Quan Huang et al.   Current Rheumatology Reports

CD19 Regulates Skin and Lung Fibrosis via Toll-Like Receptor Signaling in a Model of Bleomycin-Induced Scleroderma

(2008) Ayumi Yoshizaki et al.   AMERICAN JOURNAL OF PATHOLOGY

Induction of interferon‐α by scleroderma sera containing autoantibodies to topoisomerase I: Association of higher interferon‐α activity with lung fibrosis

(2008) Daniel Kim et al.   ARTHRITIS AND RHEUMATISM

Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: Toll-like receptor expression in early and longstanding arthritis

(2008) Caroline Ospelt et al.   ARTHRITIS AND RHEUMATISM

Inflammatory stimuli accelerate Sjögren's syndrome–like disease in (NZB × NZW)F1 mice

(2008) Umesh S. Deshmukh et al.   ARTHRITIS AND RHEUMATISM

TLR9/TLR7-triggered downregulation of BDCA2 expression on human plasmacytoid dendritic cells from healthy individuals and lupus patients

(2008) Pingping Wu et al.   CLINICAL IMMUNOLOGY

Clinical Significance of Serum HMGB-1 and sRAGE Levels in Systemic Sclerosis: Association with Disease Severity

(2008) Ayumi Yoshizaki et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toll-like receptor 9 in murine lupus: More friend than foe!

(2007) Philipp Yu et al.   IMMUNOBIOLOGY

The regulation of matrix metalloproteinases and their inhibitors

(2007) I CLARK et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY