Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control

In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect

(2010) Thomas Bjarnsholt et al.   Nature Protocols

Computer-Aided Identification of Recognized Drugs as Pseudomonas aeruginosa Quorum-Sensing Inhibitors

(2009) L. Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

(2009) MARIA VAN GENNIP et al.   APMIS

Pseudomonas aeruginosaquorum-sensing signal molecules interfere with dendritic cell-induced T-cell proliferation

(2009) Mette E. Skindersoe et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Nitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal

(2009) N. Barraud et al.   JOURNAL OF BACTERIOLOGY

Nonrandom Distribution of Pseudomonas aeruginosa and Staphylococcus aureus in Chronic Wounds

(2009) M. Fazli et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Covalent Inhibition of Bacterial Quorum Sensing

(2009) Neri Amara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

(2009) M. Alhede et al.   MICROBIOLOGY-SGM

Pyoverdine and PQS mediated subpopulation interactions involved in Pseudomonas aeruginosa biofilm formation

(2009) Liang Yang et al.   MOLECULAR MICROBIOLOGY

Characterization of starvation-induced dispersion inPseudomonas putidabiofilms: genetic elements and molecular mechanisms

(2009) Morten Gjermansen et al.   MOLECULAR MICROBIOLOGY

Pseudomonas aeruginosabiofilms in the respiratory tract of cystic fibrosis patients

(2009) Thomas Bjarnsholt et al.   PEDIATRIC PULMONOLOGY

Pseudomonas aeruginosa PAO1 Preferentially Grows as Aggregates in Liquid Batch Cultures and Disperses upon Starvation

(2009) David Schleheck et al.   PLoS One

A low concentration of azithromycin inhibits the mRNA expression of N-acyl homoserine lactone synthesis enzymes, upstream of lasI or rhlI, in Pseudomonas aeruginosa

(2009) Toshihiro Kai et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

A Novel Signaling Network Essential for Regulating Pseudomonas aeruginosa Biofilm Development

(2009) Olga E. Petrova et al.   PLoS Pathogens

Effects of Antibiotics on Quorum Sensing in Pseudomonas aeruginosa

(2008) M. E. Skindersoe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

ThePseudomonas aeruginosaautoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells

(2008) SØREN KRISTIANSEN et al.   APMIS

Emergence of Secretion-Defective Sublines of Pseudomonas aeruginosa PAO1 Resulting from Spontaneous Mutations in the vfr Global Regulatory Gene

(2008) A. Fox et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Furanone derivatives as quorum-sensing antagonists of Pseudomonas aeruginosa

(2008) Cheoljin Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Evaluation of a focused library of N-aryl l-homoserine lactones reveals a new set of potent quorum sensing modulators

(2008) Grant D. Geske et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Comparative Analyses ofN-Acylated Homoserine Lactones Reveal Unique Structural Features that Dictate Their Ability to Activate or Inhibit Quorum Sensing

(2008) Grant D. Geske et al.   CHEMBIOCHEM

Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria

(2008) Grant D. Geske et al.   CHEMICAL SOCIETY REVIEWS

Quorum-sensing signals in the microbial community of the cabbage white butterfly larval midgut

(2008) Bradley R Borlee et al.   ISME Journal

A Fatty Acid Messenger Is Responsible for Inducing Dispersion in Microbial Biofilms

(2008) D. G. Davies et al.   JOURNAL OF BACTERIOLOGY

Distribution, Organization, and Ecology of Bacteria in Chronic Wounds

(2008) K. Kirketerp-Moller et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience

(2008) C.R. Hansen et al.   Journal of Cystic Fibrosis

Solenopsin A, a Venom Alkaloid from the Fire AntSolenopsis invicta,Inhibits Quorum‐Sensing Signaling inPseudomonas aeruginosa

(2008) Junguk Park et al.   JOURNAL OF INFECTIOUS DISEASES

Quorum sensing by 2-alkyl-4-quinolones in Pseudomonas aeruginosa and other bacterial species

(2008) Jean-Frédéric Dubern et al.   Molecular BioSystems

Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes

(2008) Sünje Johanna Pamp et al.   MOLECULAR MICROBIOLOGY

Extracellular DNA Chelates Cations and Induces Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

(2008) Heidi Mulcahy et al.   PLoS Pathogens

agr-Mediated Dispersal of Staphylococcus aureus Biofilms

(2008) Blaise R. Boles et al.   PLoS Pathogens

Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa

(2007) Margrith E. Mattmann et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Why chronic wounds will not heal: a novel hypothesis

(2007) Thomas Bjarnsholt et al.   WOUND REPAIR AND REGENERATION