Sexual dimorphism in immunity: improving our understanding of vaccine immune responses in men

Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus

(2014) Benjamin R. Umiker et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Sex-based Biology and the Rational Design of Influenza Vaccination Strategies

(2014) S. L. Klein et al.   JOURNAL OF INFECTIOUS DISEASES

17 -Estradiol Protects Females against Influenza by Recruiting Neutrophils and Increasing Virus-Specific CD8 T Cell Responses in the Lungs

(2014) D. P. Robinson et al.   JOURNAL OF VIROLOGY

Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy

(2014) Daisuke Nakada et al.   NATURE

TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 mice

(2014) B. Desnues et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease

(2013) L. K. Case et al.   GENOME RESEARCH

Gender Bias in Autoimmunity Is Influenced by Microbiota

(2013) Leonid Yurkovetskiy et al.   IMMUNITY

Overexpression of X-Linked genes in T cells from women with lupus

(2013) Anura Hewagama et al.   JOURNAL OF AUTOIMMUNITY

The intracellular progesterone receptor regulates CD4+ T cells and T cell-dependent antibody responses

(2013) G. C. Hughes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Apoptosis and other immune biomarkers predict influenza vaccine responsiveness

(2013) D. Furman et al.   Molecular Systems Biology

Sex Bias in Infectious Disease Epidemiology: Patterns and Processes

(2013) Felipe Guerra-Silveira et al.   PLoS One

Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination

(2013) D. Furman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Personalized vaccinology: One size and dose might not fit both sexes

(2013) Sabra L. Klein et al.   VACCINE

Absence of LTB4/BLT1 axis facilitates generation of mouse GM-CSF-induced long-lasting antitumor immunologic memory by enhancing innate and adaptive immune systems

(2012) Y. Yokota et al.   BLOOD

Circulating sphingosine-1-phosphate and erythrocyte sphingosine kinase-1 activity as novel biomarkers for early prostate cancer detection

(2012) J Nunes et al.   BRITISH JOURNAL OF CANCER

Neuronal Androgen Receptor Regulates Insulin Sensitivity via Suppression of Hypothalamic NF- B-Mediated PTP1B Expression

(2012) I.-C. Yu et al.   DIABETES

Immune Cells Have Sex and So Should Journal Articles

(2012) Sabra L. Klein   ENDOCRINOLOGY

Estradiol increases hematopoietic stem and progenitor cells independent of its actions on bone

(2012) A. Illing et al.   HAEMATOLOGICA

Estrogen receptors regulate an inflammatory pathway of dendritic cell differentiation: Mechanisms and implications for immunity

(2012) Susan Kovats   HORMONES AND BEHAVIOR

Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome

(2012) Fadi J Charchar et al.   LANCET

Immunological complications of obesity

(2012) Thirumala-Devi Kanneganti et al.   NATURE IMMUNOLOGY

Chromosome Y Regulates Survival Following Murine Coxsackievirus B3 Infection

(2012) Laure K. Case et al.   G3-Genes Genomes Genetics

X-chromosome-located microRNAs in immunity: Might they explain male/female differences?

(2011) Iris Pinheiro et al.   BIOESSAYS

The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor   signaling

(2011) C. Seillet et al.   BLOOD

Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection

(2011) John R. Teijaro et al.   CELL

Genes that escape from X inactivation

(2011) Joel B. Berletch et al.   HUMAN GENETICS

Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies

(2011) Sanae Sasaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Sex, Race, and Geographic Region Influence Clinical Outcomes Following Primary HIV-1 Infection

(2011) Amie L. Meditz et al.   JOURNAL OF INFECTIOUS DISEASES

Thyroxine is a potential endogenous antagonist of macrophage migration inhibitory factor (MIF) activity

(2011) Y. Al-Abed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive immunity to rhinoviruses: sex and age matter

(2011) Melanie L Carroll et al.   RESPIRATORY RESEARCH

Antibody responses and cross protection against lethal influenza A viruses differ between the sexes in C57BL/6 mice

(2011) Maria E. Lorenzo et al.   VACCINE

Elevated 17β-Estradiol Protects Females from Influenza A Virus Pathogenesis by Suppressing Inflammatory Responses

(2011) Dionne P. Robinson et al.   PLoS Pathogens

Sex Hormone Regulation of Innate Immunity in the Female Reproductive Tract: The Role of Epithelial Cells in Balancing Reproductive Potential with Protection against Sexually Transmitted Pathogens

(2010) Charles R. Wira et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

17β-Estradiol Inhibits IL-8 in Cystic Fibrosis by Up-Regulating Secretory Leucoprotease Inhibitor

(2010) Sanjay H. Chotirmall et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double-blinded placebo-controlled Moscow study

(2010) Svetlana Y. Kalinchenko et al.   CLINICAL ENDOCRINOLOGY

Estrogen Receptors in Immunity and Autoimmunity

(2010) Melissa Cunningham et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Early Menopause Is Associated With Lack of Response to Antiviral Therapy in Women With Chronic Hepatitis C

(2010) Erica Villa et al.   GASTROENTEROLOGY

GPRC6A Mediates the Non-genomic Effects of Steroids

(2010) Min Pi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Testosterone Undecanoate on Cardiovascular Risk Factors and Atherosclerosis in Middle-Aged Men with Late-Onset Hypogonadism and Metabolic Syndrome: Results from a 24-month, Randomized, Double-Blind, Placebo-Controlled Study

(2010) Antonio Aversa et al.   Journal of Sexual Medicine

The Xs and Y of immune responses to viral vaccines

(2010) Sabra L Klein et al.   LANCET INFECTIOUS DISEASES

Estradiol inhibits ongoing autoimmune neuroinflammation and NF B-dependent CCL2 expression in reactive astrocytes

(2010) S. N. Giraud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NF-κB Regulates Androgen Receptor Expression and Prostate Cancer Growth

(2009) Liying Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

The induction of the lupus phenotype by estrogen is via an estrogen receptor-α-dependent pathway

(2009) Feng Feng et al.   CLINICAL IMMUNOLOGY

Estimating hepatitis C infection acquired in England, 1986–2000

(2009) M. A. BALOGUN et al.   EPIDEMIOLOGY AND INFECTION

Identification of androgen response elements in the enhancer I of hepatitis B virus: A mechanism for sex disparity in chronic hepatitis B

(2009) Sheng-Han Wang et al.   HEPATOLOGY

Progesterone-mediated immunomodulation in pregnancy: its relevance to leukocyte immunotherapy of recurrent miscarriage

(2009) Julia Szekeres-Bartho   Immunotherapy

Estrogen Regulates Transcription Factors STAT-1 and NF- B to Promote Inducible Nitric Oxide Synthase and Inflammatory Responses

(2009) R. Dai et al.   JOURNAL OF IMMUNOLOGY

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection

(2009) G. Yeretssian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

(2009) C. O. Jacob et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Half- vs Full-Dose Trivalent Inactivated Influenza Vaccine (2004-2005)

(2008) Renata J. M. Engler   ARCHIVES OF INTERNAL MEDICINE

Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: Support for the notion of a gene-dose effect from the X chromosome

(2008) R. Hal Scofield et al.   ARTHRITIS AND RHEUMATISM

Immune activation suppresses plasma testosterone level: a meta-analysis

(2008) J. J. Boonekamp et al.   Biology Letters

Gender-Dependent HLA-DR-Restricted Epitopes Identified from Herpes Simplex Virus Type 1 Glycoprotein D

(2008) X. Zhang et al.   Clinical and Vaccine Immunology

Androgen Receptor Is a New Potential Therapeutic Target for the Treatment of Hepatocellular Carcinoma

(2008) Weng–Lung Ma et al.   GASTROENTEROLOGY

A Prescription for Human Immunology

(2008) Mark M. Davis   IMMUNITY

Estrogen is a modulator of vascular inflammation

(2008) Subhadeep Chakrabarti et al.   IUBMB LIFE

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

(2008) Denis Gaucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

Sexual dimorphism of humoral immunity with human vaccines

(2008) Ian Francis Cook   VACCINE