Application of wheat germ cell-free protein expression system for novel malaria vaccine candidate discovery

Cell-free translation of peptides and proteins:from high throughput screening to clinical production

(2013) Christopher J Murray et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

RALP1 Is a Rhoptry Neck Erythrocyte-Binding Protein of Plasmodium falciparum Merozoites and a Potential Blood-Stage Vaccine Candidate Antigen

(2013) Daisuke Ito et al.   INFECTION AND IMMUNITY

Identification and Prioritization of Merozoite Antigens as Targets of Protective Human Immunity to Plasmodium falciparum Malaria for Vaccine and Biomarker Development

(2013) J. S. Richards et al.   JOURNAL OF IMMUNOLOGY

Immune mechanisms in malaria: new insights in vaccine development

(2013) Eleanor M Riley et al.   NATURE MEDICINE

Qualification of Standard Membrane-Feeding Assay with Plasmodium falciparum Malaria and Potential Improvements for Future Assays

(2013) Kazutoyo Miura et al.   PLoS One

Phase 1b Randomized Trial and Follow-Up Study in Uganda of the Blood-Stage Malaria Vaccine Candidate BK-SE36

(2013) Nirianne Marie Q. Palacpac et al.   PLoS One

PfSET10, a Plasmodium falciparum Methyltransferase, Maintains the Active var Gene in a Poised State during Parasite Division

(2012) Jennifer C. Volz et al.   Cell Host & Microbe

Biosynthesis, Localization, and Macromolecular Arrangement of thePlasmodium falciparumTranslocon of Exported Proteins (PTEX)

(2012) Hayley E. Bullen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Insights into Acquisition, Boosting, and Longevity of Immunity to Malaria in Pregnant Women

(2012) Freya JI. Fowkes et al.   JOURNAL OF INFECTIOUS DISEASES

Systematic analysis of natural antibody responses to P. falciparum merozoite antigens by protein arrays

(2012) Yan-Ting Fan et al.   Journal of Proteomics

A review of malaria vaccine clinical projects based on the WHO rainbow table

(2012) Lauren Schwartz et al.   MALARIA JOURNAL

Vaccines: The take-home lesson

(2012) Sarah DeWeerdt   NATURE

Perspectives: The missing pieces

(2012) Brendan S. Crabb et al.   NATURE

A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Pv12, a 6-Cys antigen of Plasmodium vivax, is localized to the merozoite rhoptry

(2012) Jian Li et al.   PARASITOLOGY INTERNATIONAL

Targeting Sialic Acid Dependent and Independent Pathways of Invasion in Plasmodium falciparum

(2012) Rosalynn Louise Ord et al.   PLoS One

Immunity to Malaria in Plasmodium vivax Infection: A Study in Central China

(2012) Kulachart Jangpatarapongsa et al.   PLoS One

Autophagy-Related Atg8 Localizes to the Apicoplast of the Human Malaria Parasite Plasmodium falciparum

(2012) Kei Kitamura et al.   PLoS One

Antibodies against a Plasmodium falciparum antigen PfMSPDBL1 inhibit merozoite invasion into human erythrocytes

(2012) Hirokazu Sakamoto et al.   VACCINE

Cell-free synthesis, reconstitution, and characterization of a mitochondrial dicarboxylate–tricarboxylate carrier of Plasmodium falciparum

(2011) Akira Nozawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell-free protein synthesis: Applications come of age

(2011) Erik D. Carlson et al.   BIOTECHNOLOGY ADVANCES

N-Terminal Prodomain of Pfs230 Synthesized Using a Cell-Free System Is Sufficient To Induce Complement-Dependent Malaria Transmission-Blocking Activity

(2011) Mayumi Tachibana et al.   Clinical and Vaccine Immunology

A Plant-Produced Pfs230 Vaccine Candidate Blocks Transmission of Plasmodium falciparum

(2011) Christine E. Farrance et al.   Clinical and Vaccine Immunology

Discovery of GAMA, a Plasmodium falciparum Merozoite Micronemal Protein, as a Novel Blood-Stage Vaccine Candidate Antigen

(2011) Thangavelu U. Arumugam et al.   INFECTION AND IMMUNITY

Plasmodium vivax: comparison of immunogenicity among proteins expressed in the cell-free systems of Escherichia coli and wheat germ by suspension array assays

(2011) Edmilson Rui et al.   MALARIA JOURNAL

Protection against Malaria by MSP3 Candidate Vaccine

(2011) Sodiomon B. Sirima et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Field Trial to Assess a Blood-Stage Malaria Vaccine

(2011) Mahamadou A. Thera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Plasmodial ortholog of Toxoplasma gondii rhoptry neck protein 3 is localized to the rhoptry body

(2011) Daisuke Ito et al.   PARASITOLOGY INTERNATIONAL

Measurement of naturally acquired humoral immune responses against the C-terminal region of the Plasmodium vivax MSP1 protein using protein arrays

(2011) Jun-Hu Chen et al.   PARASITOLOGY RESEARCH

Serologic Markers in Relation to Parasite Exposure History Help to Estimate Transmission Dynamics of Plasmodium vivax

(2011) Fadile Yildiz Zeyrek et al.   PLoS One

Current status ofPlasmodium vivaxvaccine

(2010) Myriam Arévalo-Herrera et al.   Human vaccines & immunotherapeutics

PATH Malaria Vaccine Initiative (MVI): Perspectives on the status of malaria vaccine development

(2010) Ashley J. Birkett   Human vaccines & immunotherapeutics

Slowing Bacterial Translation Speed Enhances Eukaryotic Protein Folding Efficiency

(2010) Efraín Siller et al.   JOURNAL OF MOLECULAR BIOLOGY

Immunoproteomics Profiling of Blood StagePlasmodium vivaxInfection by High-Throughput Screening Assays

(2010) Jun-Hu Chen et al.   JOURNAL OF PROTEOME RESEARCH

The Dynamics of Naturally Acquired Immune Responses to Plasmodium falciparum Sexual Stage Antigens Pfs230 & Pfs48/45 in a Low Endemic Area in Tanzania

(2010) Teun Bousema et al.   PLoS One

The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis

(2010) Freya J. I. Fowkes et al.   PLOS MEDICINE

Three Members of the 6-cys Protein Family of Plasmodium Play a Role in Gamete Fertility

(2010) Melissa R. van Dijk et al.   PLoS Pathogens

Novel Putative Glycosylphosphatidylinositol-Anchored Micronemal Antigen ofPlasmodium falciparumThat Binds to Erythrocytes

(2009) Louise Hinds et al.   EUKARYOTIC CELL

Wheat germ cell-free technology for accelerating the malaria vaccine research

(2009) Satoru Takeo et al.   Expert Opinion on Drug Discovery

The future for blood-stage vaccines against malaria

(2009) Jack S Richards et al.   IMMUNOLOGY AND CELL BIOLOGY

Enzymatic characterization of the Plasmodium vivax chitinase, a potential malaria transmission-blocking target

(2009) Satoru Takeo et al.   PARASITOLOGY INTERNATIONAL

Blood Stage Malaria Vaccine Eliciting High Antigen-Specific Antibody Concentrations Confers No Protection to Young Children in Western Kenya

(2009) Bernhards R. Ogutu et al.   PLoS One

Sterile Protection against Plasmodium knowlesi in Rhesus Monkeys from a Malaria Vaccine: Comparison of Heterologous Prime Boost Strategies

(2009) George Jiang et al.   PLoS One

Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design

(2009) K. M. VanBuskirk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence

(2009) H. Otsuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasmodium berghei HAP2 induces strong malaria transmission-blocking immunity in vivo and in vitro

(2009) Andrew M. Blagborough et al.   VACCINE

Malaria vaccines: a toy for travelers or a tool for eradication?

(2008) Blaise Genton   Expert Review of Vaccines

Characterization of a Conserved Rhoptry-Associated Leucine Zipper-Like Protein in the Malaria Parasite Plasmodium falciparum

(2008) S. Haase et al.   INFECTION AND IMMUNITY

Wheat Germ Cell-Free System-Based Production of Malaria Proteins for Discovery of Novel Vaccine Candidates

(2008) T. Tsuboi et al.   INFECTION AND IMMUNITY

Human protein factory for converting the transcriptome into an in vitro–expressed proteome

(2008) Naoki Goshima et al.   NATURE METHODS

Pyruvate kinase type-II isozyme in Plasmodium falciparum localizes to the apicoplast

(2008) Takuya Maeda et al.   PARASITOLOGY INTERNATIONAL

Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites

(2008) Jun Cao et al.   PARASITOLOGY INTERNATIONAL

Phase 1 Trial of Malaria Transmission Blocking Vaccine Candidates Pfs25 and Pvs25 Formulated with Montanide ISA 51

(2008) Yimin Wu et al.   PLoS One

Profiling humoral immune responses to P. falciparum infection with protein microarrays

(2008) Denise L. Doolan et al.   PROTEOMICS