TLR4 agonists as vaccine adjuvants: a chemist’s perspective

Synthesis and immunomodulatory activities of Helicobacter pylori lipophilic terminus of lipopolysaccharide including lipid A

(2012) Yukari Fujimoto et al.   CARBOHYDRATE RESEARCH

Glucopyranosyl Lipid Adjuvant (GLA), a Synthetic TLR4 Agonist, Promotes Potent Systemic and Mucosal Responses to Intranasal Immunization with HIVgp140

(2012) Mauricio A. Arias et al.   PLoS One

Selective TRIF-Dependent Signaling by a Synthetic Toll-Like Receptor 4 Agonist

(2012) W. S. Bowen et al.   Science Signaling

MF59 oil-in-water emulsion in combination with a synthetic TLR4 agonist (E6020) is a potent adjuvant for a combination Meningococcus vaccine

(2012) Manmohan Singh et al.   Human Vaccines & Immunotherapeutics

GLA-SE, a Synthetic Toll-like Receptor 4 Agonist, Enhances T-Cell Responses to Influenza Vaccine in Older Adults

(2011) Hayedeh Behzad et al.   JOURNAL OF INFECTIOUS DISEASES

The safety evaluation of adjuvants during vaccine development: The AS04 experience

(2011) Nathalie Garçon et al.   VACCINE

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease

(2009) Courtney-S Schaffert   WORLD JOURNAL OF GASTROENTEROLOGY

The ‘Ethereal’ nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics

(2008) Hélène G. Bazin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthetic TLR4-active Glycolipids as Vaccine Adjuvants and Stand-alone Immunotherapeutics

(2008) David Johnson   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Increased immunogenicity to P815 cells modified with malondialdehyde and acetaldehyde

(2008) Michael J. Duryee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY