Carbohydrate-based Clostridium difficile vaccines

Phosphorylation of the Synthetic Hexasaccharide Repeating Unit Is Essential for the Induction of Antibodies to Clostridium difficile PSII Cell Wall Polysaccharide

(2012) Roberto Adamo et al.   ACS Chemical Biology

Efficacy of LFF571 in a Hamster Model of Clostridium difficile Infection

(2012) Anna Trzasko et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clostridium difficile carbohydrates: glucan in spores, PSII common antigen in cells, immunogenicity of PSII in swine and synthesis of a dual C. difficile–ETEC conjugate vaccine

(2012) Lisa Bertolo et al.   CARBOHYDRATE RESEARCH

Structural characterization of surface glycans from Clostridium difficile

(2012) Christopher W. Reid et al.   CARBOHYDRATE RESEARCH

Immunization strategies forClostridium difficileinfections

(2012) Fabien Rebeaud et al.   Expert Review of Vaccines

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

(2012) Jeremiah R. McDole et al.   NATURE

Effects of adjuvants on the immune response of pigs after intradermal administration of antigen

(2012) Josef Krejci et al.   RESEARCH IN VETERINARY SCIENCE

Progress toward developing a carbohydrate-conjugate vaccine against Clostridium difficile ribotype 027: synthesis of the cell-surface polysaccharide PS-I repeating unit

(2011) Christopher E. Martin et al.   CHEMICAL COMMUNICATIONS

A Possible Oligosaccharide-Conjugate Vaccine Candidate for Clostridium difficile Is Antigenic and Immunogenic

(2011) Matthias A. Oberli et al.   CHEMISTRY & BIOLOGY

Humoral Immune Response to Keyhole Limpet Haemocyanin, the Protein Carrier in Cancer Vaccines

(2011) A. Kantele et al.   Clinical & Developmental Immunology

Phagocytes: Fussy about Carbs

(2011) Ann M. Kerrigan et al.   CURRENT BIOLOGY

Response to Cutaneous Immunization with Low-Molecular-Weight Subunit Keyhole Limpet Hemocyanin

(2011) Henry Milgrom et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Vaccination With Parenteral Toxoid B Protects Hamsters Against Lethal Challenge With Toxin A–Negative, Toxin B–Positive Clostridium difficile but Does Not Prevent Colonization

(2011) Farida Siddiqui et al.   JOURNAL OF INFECTIOUS DISEASES

Clostridium difficile in horses in Australia - a preliminary study

(2011) S. Thean et al.   JOURNAL OF MEDICAL MICROBIOLOGY

How vitamin A metabolizing dendritic cells are generated in the gut mucosa

(2011) William W. Agace et al.   TRENDS IN IMMUNOLOGY

Clostridium difficile infection in humans and animals, differences and similarities

(2011) E.C. Keessen et al.   VETERINARY MICROBIOLOGY

TEMPO-mediated glycoconjugation: a scheme for the controlled synthesis of polysaccharide conjugates

(2010) Zuchao Ma et al.   CARBOHYDRATE RESEARCH

Enemy at the gates: dendritic cells and immunity to mucosal pathogens

(2010) Adam C Soloff et al.   CELL RESEARCH

Update on Clostridium difficile infection

(2010) Caoilfhionn OʼDonoghue et al.   CURRENT OPINION IN GASTROENTEROLOGY

Langerin-expressing dendritic cells in gut-associated lymphoid tissues

(2010) Sun-Young Chang et al.   IMMUNOLOGICAL REVIEWS

Characterization of the Enzymes Encoded by the Anthrose Biosynthetic Operon of Bacillus anthracis

(2010) S. Dong et al.   JOURNAL OF BACTERIOLOGY

Impact of Polymorphisms of the Genes Encoding Angiotensin II-Forming Enzymes on the Progression of IgA Nephropathy

(2010) Eun Sook Jung et al.   NEPHRON CLINICAL PRACTICE

Treatment with Monoclonal Antibodies againstClostridium difficileToxins

(2010) Israel Lowy et al.   NEW ENGLAND JOURNAL OF MEDICINE

First Synthesis ofC. difficilePS-II Cell Wall Polysaccharide Repeating Unit

(2010) Elisa Danieli et al.   ORGANIC LETTERS

Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis

(2010) T. Obata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

(2010) S. Hapfelmeier et al.   SCIENCE

The potential value of Clostridium difficile vaccine: An economic computer simulation model

(2010) Bruce Y. Lee et al.   VACCINE

Acquisition of Clostridium difficile by piglets

(2010) N.E.M. Hopman et al.   VETERINARY MICROBIOLOGY

Bioaccumulation of Amylose-Like Glycans byHelicobacter pylori

(2009) José A. Ferreira et al.   HELICOBACTER

Identification of Mycobacterial  -Glucan As a Novel Ligand for DC-SIGN: Involvement of Mycobacterial Capsular Polysaccharides in Host Immune Modulation

(2009) J. Geurtsen et al.   JOURNAL OF IMMUNOLOGY

Piglet Models of Acute or ChronicClostridium difficileIllness

(2009) Jennifer Steele et al.   JOURNAL OF INFECTIOUS DISEASES

A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota

(2009) Y. Cong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of the administration of a fermented milk containing Lactobacillus casei DN-114001 on intestinal microbiota and gut associated immune cells of nursing mice and after weaning until immune maturity

(2008) Alejandra de Moreno de LeBlanc et al.   BMC IMMUNOLOGY

Clostridium difficile cell-surface polysaccharides composed of pentaglycosyl and hexaglycosyl phosphate repeating units

(2008) Jeyabarathy Ganeshapillai et al.   CARBOHYDRATE RESEARCH

A Mouse Model of Clostridium difficile–Associated Disease

(2008) Xinhua Chen et al.   GASTROENTEROLOGY

Requirement for Lymphoid Tissue-Inducer Cells in Isolated Follicle Formation and T Cell-Independent Immunoglobulin A Generation in the Gut

(2008) Masayuki Tsuji et al.   IMMUNITY

Capsule Polysaccharide Conjugate Vaccine against Diarrheal Disease Caused by Campylobacter jejuni

(2008) M. A. Monteiro et al.   INFECTION AND IMMUNITY

Immunoreactive cell wall proteins of Clostridium difficile identified by human sera

(2008) A. Wright et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Clostridium difficile— More Difficult Than Ever

(2008) Ciarán P. Kelly et al.   NEW ENGLAND JOURNAL OF MEDICINE

A prospective study of the roles of Clostridium difficile and enterotoxigenic Clostridium perfringens in equine diarrhoea

(2007) J. S. WEESE et al.   EQUINE VETERINARY JOURNAL

Keyhole limpet hemocyanin induces the activation and maturation of human dendritic cells through the involvement of mannose receptor

(2007) Pietro Presicce et al.   MOLECULAR IMMUNOLOGY