Understanding the immune response to seasonal influenza vaccination in older adults: a systems biology approach

Clonal Expansions and Loss of Receptor Diversity in the Naive CD8 T Cell Repertoire of Aged Mice

(2014) M. Ahmed et al.   JOURNAL OF IMMUNOLOGY

Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice

(2012) Nathan W. Cummins et al.   FASEB JOURNAL

Vaccinomics: Current Findings, Challenges and Novel Approaches for Vaccine Development

(2011) Inna G. Ovsyannikova et al.   AAPS Journal

Systems biology approaches to new vaccine development

(2011) Ann L Oberg et al.   CURRENT OPINION IN IMMUNOLOGY

Seasonality – still confusing

(2011) S. F. DOWELL   EPIDEMIOLOGY AND INFECTION

Vaccinomics and a New Paradigm for the Development of Preventive Vaccines Against Viral Infections

(2011) Gregory A. Poland et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Elderly Subjects Have a Delayed Antibody Response and Prolonged Viraemia following Yellow Fever Vaccination: A Prospective Controlled Cohort Study

(2011) Anna H. Roukens et al.   PLoS One

Humoral and Cell-Mediated Immunity to Pandemic H1N1 Influenza in a Canadian Cohort One Year Post-Pandemic: Implications for Vaccination

(2011) Lisa E. Wagar et al.   PLoS One

Developing vaccine policy: Attributes of “just policy” and a proposed template to guide decision and policy making

(2011) Gregory A. Poland et al.   VACCINE

Age-related changes in memory and effector T cells responding to influenza A/H3N2 and pandemic A/H1N1 strains in humans

(2011) Xin Zhou et al.   VACCINE

Antibody and Th1-type cell-mediated immune responses in elderly and young adults immunized with the standard or a high dose influenza vaccine

(2011) Wilbur H. Chen et al.   VACCINE

Vaccinomics and Personalized Vaccinology: Is Science Leading Us Toward a New Path of Directed Vaccine Development and Discovery?

(2011) Gregory A. Poland et al.   PLoS Pathogens

Decline of influenza-specific CD8+ T cell repertoire in healthy geriatric donors

(2011) Jessica B Lee et al.   Immunity & Ageing

Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity

(2010) Aishwarya Sridharan et al.   AGE

Systems Biology: An Approach

(2010) P Kohl et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Vaccinomics, predictive vaccinology and the future of vaccine development

(2010) Iana H Haralambieva et al.   Future Microbiology

Systems Vaccinology

(2010) Bali Pulendran et al.   IMMUNITY

Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response

(2010) Alexander Panda et al.   JOURNAL OF IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Reduction of Natural Killer but Not Effector CD8 T Lymphoyctes in Three Consecutive Cases of Severe/Lethal H1N1/09 Influenza A Virus Infection

(2010) Laura Denney et al.   PLoS One

Developing the next generation of vaccinologists

(2010) Gregory A. Poland et al.   VACCINE

Clinical and immunologic predictors of influenza illness among vaccinated older adults

(2010) Zainab Shahid et al.   VACCINE

Absolute Humidity and the Seasonal Onset of Influenza in the Continental United States

(2010) Jeffrey Shaman et al.   PLOS BIOLOGY

Aging Promotes Neutrophil-Induced Mortality by Augmenting IL-17 Production during Viral Infection

(2009) Heather W. Stout-Delgado et al.   Cell Host & Microbe

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Randomized, Double‐Blind Controlled Phase 3 Trial Comparing the Immunogenicity of High‐Dose and Standard‐Dose Influenza Vaccine in Adults 65 Years of Age and Older

(2009) Ann R. Falsey et al.   JOURNAL OF INFECTIOUS DISEASES

TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection

(2009) J. R. Aldridge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus

(2008) Eric J. Yager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vaccinia virus strain NYVAC induces substantially lower and qualitatively different human antibody responses compared with strains Lister and Dryvax

(2008) C. M. Midgley et al.   JOURNAL OF GENERAL VIROLOGY

Varicella Vaccination of Immunocompromised Children

(2008) Myron J. Levin   JOURNAL OF INFECTIOUS DISEASES

Dysregulation of TLR3 Impairs the Innate Immune Response to West Nile Virus in the Elderly

(2008) K.-F. Kong et al.   JOURNAL OF VIROLOGY

A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology

(2008) Markus J Herrgård et al.   NATURE BIOTECHNOLOGY

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

Immunogenetics of seasonal influenza vaccine response

(2008) Gregory A. Poland et al.   VACCINE

Age-related appearance of a CMV-specific high-avidity CD8+ T cell clonotype which does not occur in young adults

(2008) Angelika Schwanninger et al.   Immunity & Ageing

Human Genes and Influenza

(2007) Samira Mubareka et al.   JOURNAL OF INFECTIOUS DISEASES

Evidence for a Heritable Predisposition to Death Due to Influenza

(2007) Frederick S. Albright et al.   JOURNAL OF INFECTIOUS DISEASES