The future of cell culture-based influenza vaccine production

United States of America Department of Health and Human Services support for advancing influenza vaccine manufacturing in the developing world

(2011) Michael L. Perdue et al.   VACCINE

Development and strategies of cell-culture technology for influenza vaccine

(2010) Shao-Zhen Feng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Production of cell culture (MDCK) derived live attenuated influenza vaccine (LAIV) in a fully disposable platform process

(2010) Meena George et al.   BIOTECHNOLOGY AND BIOENGINEERING

Cell Culture–Derived Influenza Vaccines: Has Their Time Come?

(2010) David I. Bernstein   CLINICAL INFECTIOUS DISEASES

Vaccines against Seasonal and Pandemic Influenza and the Implications of Changes in Substrates for Virus Production

(2010) Philip D. Minor   CLINICAL INFECTIOUS DISEASES

Clinical Efficacy of Cell Culture–Derived and Egg‐Derived Inactivated Subunit Influenza Vaccines in Healthy Adults

(2010) Sharon Frey et al.   CLINICAL INFECTIOUS DISEASES

Vaccination strategies and vaccine formulations for epidemic and pandemic influenza control

(2010) Joost H.C.M. Kreijtz et al.   Human vaccines & immunotherapeutics

Emerging Trends: Vaccines in late development

(2010) R.L. Atmar   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Influenza is a Major Contributor to Childhood Pneumonia in a Tropical Developing Country

(2010) W Abdullah Brooks et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Global production of seasonal and pandemic (H1N1) influenza vaccines in 2009–2010 and comparison with previous estimates and global action plan targets

(2010) Jeffrey Partridge et al.   VACCINE

Evaluation of the cellular immune responses induced by a non-adjuvanted inactivated whole virus A/H5N1/VN/1203 pandemic influenza vaccine in humans

(2010) Brian A. Crowe et al.   VACCINE

Comparison of egg and high yielding MDCK cell-derived live attenuated influenza virus for commercial production of trivalent influenza vaccine: In vitro cell susceptibility and influenza virus replication kinetics in permissive and semi-permissive cells

(2010) Althaf I. Hussain et al.   VACCINE

FluBlok, a next generation influenza vaccine manufactured in insect cells

(2009) Manon M.J. Cox et al.   BIOLOGICALS

Trivalent MDCK cell culture-derived influenza vaccine Optaflu®(Novartis Vaccines)

(2009) Alexander Doroshenko et al.   Expert Review of Vaccines

Using plant cells as influenza vaccine substrates

(2009) Jessica A Chichester et al.   Expert Review of Vaccines

Influenza virus-like particle vaccines

(2009) Joel R Haynes   Expert Review of Vaccines

Vero cell platform in vaccine production: moving towards cell culture-based viral vaccines

(2009) P Noel Barrett et al.   Expert Review of Vaccines

Continuous cell lines as a production system for influenza vaccines

(2009) Yvonne Genzel et al.   Expert Review of Vaccines

Influenza Vaccine Manufacture: Keeping Up with Change

(2009) Kathleen M. Neuzil et al.   JOURNAL OF INFECTIOUS DISEASES

Safety and Immunogenicity of a Novel Influenza Subunit Vaccine Produced in Mammalian Cell Culture

(2009) Agnieszka Szymczakiewicz‐Multanowska et al.   JOURNAL OF INFECTIOUS DISEASES

Subunit Influenza Vaccines Produced from Cell Culture or in Embryonated Chicken Eggs: Comparison of Safety, Reactogenicity, and Immunogenicity

(2009) Keith S. Reisinger et al.   JOURNAL OF INFECTIOUS DISEASES

A Cell Culture (Vero)–Derived H5N1 Whole‐Virus Vaccine Induces Cross‐Reactive Memory Responses

(2009) Hartmut J. Ehrlich et al.   JOURNAL OF INFECTIOUS DISEASES

Nonreplicating Vaccinia Virus Vectors Expressing the H5 Influenza Virus Hemagglutinin Produced in Modified Vero Cells Induce Robust Protection

(2009) J. Mayrhofer et al.   JOURNAL OF VIROLOGY

Conversion of MDCK cell line to suspension culture by transfecting with human siat7e gene and its application for influenza virus production

(2009) C. Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel mammalian cell-culture technique for consistent production of a well-tolerated and immunogenic trivalent subunit influenza vaccine

(2009) Arvydas Ambrozaitis et al.   VACCINE

Suspension-Vero cell cultures as a platform for viral vaccine production

(2009) Cristian Paillet et al.   VACCINE

Safety and immunogenicity of inactivated, Vero cell culture-derived whole virus influenza A/H5N1 vaccine given alone or with aluminum hydroxide adjuvant in healthy adults

(2009) Wendy A. Keitel et al.   VACCINE

Use of MDCK cells for production of live attenuated influenza vaccine

(2009) Jonathan Liu et al.   VACCINE

Development of a live-attenuated influenza B ΔNS1 intranasal vaccine candidate

(2009) Nina Wressnigg et al.   VACCINE

Glycan analysis in cell culture-based influenza vaccine production: Influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin

(2009) Jana Schwarzer et al.   VACCINE

Current challenges in implementing cell-derived influenza vaccines: Implications for production and regulation, July 2007, NIBSC, Potters Bar, UK

(2009) Philip D. Minor et al.   VACCINE

A phase I clinical trial of a PER.C6® cell grown influenza H7 virus vaccine

(2009) Rebecca J. Cox et al.   VACCINE

Cloning and assessment of tumorigenicity and oncogenicity of a Madin–Darby canine kidney (MDCK) cell line for influenza vaccine production

(2009) Jonathan Liu et al.   VACCINE

Dose ranging of adjuvant and antigen in a cell culture H5N1 influenza vaccine: Safety and immunogenicity of a phase 1/2 clinical trial

(2009) Wendy Keitel et al.   VACCINE

Pre-clinical development of cell culture (Vero)-derived H5N1 pandemic vaccines

(2008) M. Keith Howard et al.   BIOLOGICAL CHEMISTRY

Scaling-up vaccine production: implementation aspects of a biomass growth observer and controller

(2008) Zita I. T. A. Soons et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza

(2008) J. Steel et al.   JOURNAL OF VIROLOGY

Growth Determinants for H5N1 Influenza Vaccine Seed Viruses in MDCK Cells

(2008) S. Murakami et al.   JOURNAL OF VIROLOGY

A Clinical Trial of a Whole-Virus H5N1 Vaccine Derived from Cell Culture

(2008) Hartmut J. Ehrlich et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cross-Clade Protective Immune Responses to Influenza Viruses with H5N1 HA and NA Elicited by an Influenza Virus-Like Particle

(2008) Rick A. Bright et al.   PLoS One

A quantitative risk assessment of exposure to adventitious agents in a cell culture-derived subunit influenza vaccine

(2008) Jens-Peter Gregersen   VACCINE

High titer growth of human and avian influenza viruses in an immortalized chick embryo cell line without the need for exogenous proteases

(2008) Kristen A. Smith et al.   VACCINE

Microcarrier-based MDCK cell culture system for the production of influenza H5N1 vaccines

(2008) Alan Yung-Chih Hu et al.   VACCINE

HPLC-based quantification of haemagglutinin in the production of egg- and MDCK cell-derived influenza virus seasonal and pandemic vaccines

(2008) J.C. Kapteyn et al.   VACCINE

Safety, tolerability and immunogenicity of a mammalian cell-culture-derived influenza vaccine: A sequential Phase I and Phase II clinical trial

(2008) N. Groth et al.   VACCINE