Intradermal naked plasmid DNA immunization: mechanisms of action

Modulation of Plasmid DNA Vaccine Antigen Clearance by Caspase 12 RNA Interference Potentiates Vaccination

(2011) Ralf Geiben-Lynn et al.   Clinical and Vaccine Immunology

Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity

(2011) Adrian Bot et al.   Journal of Translational Medicine

Protective Efficacy of DNA Vaccines Encoding Outer Membrane Protein A and OmpK36 ofKlebsiella pneumoniaein Mice

(2010) Prathiba Kurupati et al.   Clinical and Vaccine Immunology

Progress and prospects: nuclear import of nonviral vectors

(2010) A P Lam et al.   GENE THERAPY

Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin

(2010) Nikolaus Romani et al.   IMMUNOLOGICAL REVIEWS

Langerhans cells: critical regulators of skin immunity?

(2010) Björn E Clausen et al.   IMMUNOLOGY AND CELL BIOLOGY

Disentangling the complexity of the skin dendritic cell network

(2010) Sandrine Henri et al.   IMMUNOLOGY AND CELL BIOLOGY

Microneedles: A Valuable Physical Enhancer to Increase Transdermal Drug Delivery

(2010) José Juan Escobar-Chávez et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Directly Transfected Langerin+ Dermal Dendritic Cells Potentiate CD8+ T Cell Responses following Intradermal Plasmid DNA Immunization

(2010) M. Elnekave et al.   JOURNAL OF IMMUNOLOGY

The Role of Skin-Derived Dendritic Cells in CD8+ T Cell Priming Following Immunization with Lentivectors

(2010) K. Furmanov et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells in Distinct Oral Mucosal Tissues Engage Different Mechanisms To Prime CD8+ T Cells

(2010) I. Nudel et al.   JOURNAL OF IMMUNOLOGY

Essential Role for TLR9 in Prime but Not Prime-Boost Plasmid DNA Vaccination To Activate Dendritic Cells and Protect from Lethal Viral Infection

(2010) D. Rottembourg et al.   JOURNAL OF IMMUNOLOGY

Langerin+ Dermal Dendritic Cells Are Critical for CD8+ T Cell Activation and IgH  -1 Class Switching in Response to Gene Gun Vaccines

(2010) A. Stoecklinger et al.   JOURNAL OF IMMUNOLOGY

Functional Redundancy of Langerhans Cells and Langerin+ Dermal Dendritic Cells in Contact Hypersensitivity

(2010) Madelon Noordegraaf et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys

(2010) Sampa Santra et al.   NATURE MEDICINE

Priming Immunization with DNA Augments Immunogenicity of Recombinant Adenoviral Vectors for Both HIV-1 Specific Antibody and T-Cell Responses

(2010) Richard A. Koup et al.   PLoS One

Safety and Immunogenicity Study of Multiclade HIV-1 Adenoviral Vector Vaccine Alone or as Boost following a Multiclade HIV-1 DNA Vaccine in Africa

(2010) Walter Jaoko et al.   PLoS One

Immune response induced by a linear DNA vector: Influence of dose, formulation and route of injection

(2010) Anne Endmann et al.   VACCINE

Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands

(2009) Claudius Grossmann et al.   BMC IMMUNOLOGY

Optimization of Intradermal Vaccination by DNA Tattooing in Human Skin

(2009) Joost H. van den Berg et al.   HUMAN GENE THERAPY

Equivalent stimulation of naive and memory CD8 T cells by DNA vaccination: a dendritic cell-dependent process

(2009) Sammy Bedoui et al.   IMMUNOLOGY AND CELL BIOLOGY

Evaluation of apoptotic and anti-apoptotic genes on efficacy of DNA vaccine encoding glycoprotein B of Herpes Simplex Virus type 1

(2009) Masoud Parsania et al.   IMMUNOLOGY LETTERS

Non-classical Natural Killer T Cells Modulate Plasmid DNA Vaccine Antigen Expression and Vaccine-elicited Immune Responses by MCP-1 Secretion after Interaction with a β2-Microglobulin-independent CD1d

(2009) Ralf Geiben-Lynn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD207+CD103+dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

(2009) Sandrine Henri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Matter of Timing: Unsynchronized Antigen Expression and Antigen Presentation Diminish Secondary T Cell Responses

(2009) M. Elnekave et al.   JOURNAL OF IMMUNOLOGY

Skin-Resident T Cells: The Ups and Downs of On Site Immunity

(2009) Rachael A. Clark   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Optimization of Skin Electroporation in Mice to Increase Tolerability of DNA Vaccine Delivery to Patients

(2009) Anna-Karin Roos et al.   MOLECULAR THERAPY

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

Dendritic cell subsets in primary and secondary T cell responses at body surfaces

(2009) William R Heath et al.   NATURE IMMUNOLOGY

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions

(2009) K. Nagao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skin immune surveillance by T cells—A new order?

(2009) Jessica Strid et al.   SEMINARS IN IMMUNOLOGY

Enhancing DNA vaccination by sequential injection of lymph nodes with plasmid vectors and peptides

(2009) Kent A. Smith et al.   VACCINE

Skin-specific promoters for genetic immunisation by DNA electroporation

(2009) Gaëlle Vandermeulen et al.   VACCINE

Enhancing comparative rabies DNA vaccine effectiveness through glycoprotein gene modifications

(2009) M.O.V. Osinubi et al.   VACCINE

CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses

(2008) R. Geiben-Lynn et al.   BLOOD

Antimicrobial peptides and self-DNA in autoimmune skin inflammation

(2008) Michel Gilliet et al.   CURRENT OPINION IN IMMUNOLOGY

Intradermal NKT cell activation during DNA priming in heterologous prime-boost vaccination enhances T cell responses and protection againstLeishmania

(2008) Blaise Dondji et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-1, IL-18, and IL-33 families of cytokines

(2008) William P. Arend et al.   IMMUNOLOGICAL REVIEWS

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

(2008) Godwin Nchinda et al.   JOURNAL OF CLINICAL INVESTIGATION

DNA vaccines: ready for prime time?

(2008) Michele A. Kutzler et al.   NATURE REVIEWS GENETICS

Dendritic Cell-Induced Memory T Cell Activation in Nonlymphoid Tissues

(2008) L. M. Wakim et al.   SCIENCE

Immunogenicity and protective efficacy of a tuberculosis DNA vaccine co-expressing pro-apoptotic caspase-3

(2008) Tatiana Gartner et al.   VACCINE