Francisellavirulence: significant advances, ongoing challenges and unmet needs

Identification of migR, a Regulatory Element of the Francisella tularensis Live Vaccine Strain iglABCD Virulence Operon Required for Normal Replication and Trafficking in Macrophages

(2009) B. W. Buchan et al.   INFECTION AND IMMUNITY

Establishment of lethal inhalational infection withFrancisella tularensis(tularaemia) in the common marmoset (Callithrix jacchus)

(2009) Michelle Nelson et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Lethal pulmonary infection with Francisella novicida is associated with severe sepsis

(2009) Jyotika Sharma et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Antigen-specific B-1a antibodies induced by Francisella tularensis LPS provide long-term protection against F. tularensis LVS challenge

(2009) L. E. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant attenuated Listeria monocytogenes vaccine expressing Francisella tularensis IglC induces protection in mice against aerosolized Type A F. tularensis

(2009) Qingmei Jia et al.   VACCINE

Pathology of Inhalational Francisella tularensis spp. tularensis SCHU S4 Infection in African Green Monkeys (Chlorocebus aethiops)

(2009) N. A. Twenhafel et al.   VETERINARY PATHOLOGY

Comparative Genomic Characterization of Francisella tularensis Strains Belonging to Low and High Virulence Subspecies

(2009) Mia D. Champion et al.   PLoS Pathogens

Drosophila melanogaster as a model for elucidating the pathogenicity of Francisella tularensis

(2008) Malin Vonkavaara et al.   CELLULAR MICROBIOLOGY

Transcriptional profiling ofFrancisella tularensisinfected peripheral blood mononuclear cells: a predictive tool for tularemia

(2008) Chrysanthi Paranavitana et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Host Immune Response and Acute Disease in a Zebrafish Model of Francisella Pathogenesis

(2008) L. N. Vojtech et al.   INFECTION AND IMMUNITY

Identification of fevR, a Novel Regulator of Virulence Gene Expression in Francisella novicida

(2008) A. Brotcke et al.   INFECTION AND IMMUNITY

Diverse Myeloid and Lymphoid Cell Subpopulations Produce Gamma Interferon during Early Innate Immune Responses to Francisella tularensis Live Vaccine Strain

(2008) R. De Pascalis et al.   INFECTION AND IMMUNITY

NK Cells and Gamma Interferon Coordinate the Formation and Function of Hepatic Granulomas in Mice Infected with the Francisella tularensis Live Vaccine Strain

(2008) S. M. Bokhari et al.   INFECTION AND IMMUNITY

Acquisition of the Vacuolar ATPase Proton Pump and Phagosome Acidification Are Essential for Escape of Francisella tularensis into the Macrophage Cytosol

(2008) M. Santic et al.   INFECTION AND IMMUNITY

The Early Phagosomal Stage of Francisella tularensis Determines Optimal Phagosomal Escape and Francisella Pathogenicity Island Protein Expression

(2008) A. Chong et al.   INFECTION AND IMMUNITY

Native Outer Membrane Proteins Protect Mice against Pulmonary Challenge with Virulent Type A Francisella tularensis

(2008) J. F. Huntley et al.   INFECTION AND IMMUNITY

The Francisella Pathogenicity Island Protein PdpD Is Required for Full Virulence and Associates with Homologues of the Type VI Secretion System

(2008) J. S. Ludu et al.   JOURNAL OF BACTERIOLOGY

Francisella Genes Required for Replication in Mosquito Cells

(2008) Amanda Read et al.   JOURNAL OF MEDICAL ENTOMOLOGY

NK cells activated in vivo by bacterial DNA control the intracellular growth of Francisella tularensis LVS

(2008) K ELKINS et al.   MICROBES AND INFECTION

An improved Francisella tularensis live vaccine strain (LVS) is well tolerated and highly immunogenic when administered to rabbits in escalating doses using various immunization routes

(2008) Marcela F. Pasetti et al.   VACCINE

Protection afforded against aerosol challenge by systemic immunisation with inactivated Francisella tularensis live vaccine strain (LVS)

(2007) J.E. Eyles et al.   MICROBIAL PATHOGENESIS