Heat-shock proteins in cancer vaccines: agents of antigen cross-presentation

Both CD4+and CD8+T cell epitopes fused to heat shock cognate protein 70 (hsc70) can function to eradicate tumors

(2008) Shusaku Mizukami et al.   CANCER SCIENCE

Endocytosis mechanisms and the cell biology of antigen presentation

(2008) Sven Burgdorf et al.   CURRENT OPINION IN IMMUNOLOGY

Phase III Comparison of Vitespen, an Autologous Tumor-Derived Heat Shock Protein gp96 Peptide Complex Vaccine, With Physician's Choice of Treatment for Stage IV Melanoma: The C-100-21 Study Group

(2008) Alessandro Testori et al.   JOURNAL OF CLINICAL ONCOLOGY

Transforming Growth Factor   (TGF )-Stimulated Secretion of HSP90 : Using the Receptor LRP-1/CD91 To Promote Human Skin Cell Migration against a TGF -Rich Environment during Wound Healing

(2008) C.-F. Cheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

(2008) Sven Burgdorf et al.   NATURE IMMUNOLOGY

The dual immunoregulatory roles of stress proteins

(2008) Alan Graham Pockley et al.   TRENDS IN BIOCHEMICAL SCIENCES

A novel therapeutic fusion protein vaccine by two different families of heat shock proteins linked with HPV16 E7 generates potent antitumor immunity and antiangiogenesis

(2008) Bo Liu et al.   VACCINE