DNA-assisted protein detection technologies

Affinity reagents for lab on chips

(2011) Mathias Uhlen et al.   LAB ON A CHIP

Multiplexed Homogeneous Proximity Ligation Assays for High-throughput Protein Biomarker Research in Serological Material

(2011) Martin Lundberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Increasing the dynamic range of in situ PLA

(2011) Carl-Magnus Clausson et al.   NATURE METHODS

Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood

(2011) Martin Lundberg et al.   NUCLEIC ACIDS RESEARCH

Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery

(2011) Larry Gold et al.   PLoS One

ProteinSeq: High-Performance Proteomic Analyses by Proximity Ligation and Next Generation Sequencing

(2011) Spyros Darmanis et al.   PLoS One

Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer

(2011) G. Tavoosidana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of respiratory syncytial virus using nanoparticle amplified immuno-polymerase chain reaction

(2010) Jonas W. Perez et al.   ANALYTICAL BIOCHEMISTRY

Improvement of Sensitivity and Dynamic Range in Proximity Ligation Assays by Asymmetric Connector Hybridization

(2010) Joonyul Kim et al.   ANALYTICAL CHEMISTRY

Sensitive detection of Aβ protofibrils by proximity ligation - relevance for Alzheimer's disease

(2010) Masood Kamali-Moghaddam et al.   BMC NEUROSCIENCE

In situ quantification of HER2–protein tyrosine kinase 6 (PTK6) protein–protein complexes in paraffin sections from breast cancer tissues

(2010) M Aubele et al.   BRITISH JOURNAL OF CANCER

Proximity ligation assays: a recent addition to the proteomics toolbox

(2010) Irene Weibrecht et al.   Expert Review of Proteomics

Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine

(2010) A. Blokzijl et al.   JOURNAL OF INTERNAL MEDICINE

Interaction-Dependent PCR: Identification of Ligand−Target Pairs from Libraries of Ligands and Libraries of Targets in a Single Solution-Phase Experiment

(2010) Lynn M. McGregor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding applications of protein analysis using proximity ligation and qPCR

(2010) Elana Swartzman et al.   METHODS

A highly sensitive immuno-PCR assay for detection of H5N1 avian influenza virus

(2010) Ming Jun Deng et al.   MOLECULAR BIOLOGY REPORTS

Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations

(2010) David M Rissin et al.   NATURE BIOTECHNOLOGY

An On-Nanoparticle Rolling-Circle Amplification Platform for Ultrasensitive Protein Detection in Biological Fluids

(2010) Juan Yan et al.   Small

Generating recombinant antibodies to the complete human proteome

(2010) Stefan Dübel et al.   TRENDS IN BIOTECHNOLOGY

Immuno-PCR-based quantification of multiple phosphorylated tau-epitopes linked to Alzheimer’s disease

(2009) David Singer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Antibody-specific aptamer-based PCR analysis for sensitive protein detection

(2009) Yoshihito Yoshida et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Real-time immuno-PCR assay for detecting PCBs in soil samples

(2009) Han-Yu Chen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Protein Quantification in Complex Mixtures by Solid Phase Single-Molecule Counting

(2009) Lee A. Tessler et al.   ANALYTICAL CHEMISTRY

Diffractometric Detection of Proteins Using Microbead-Based Rolling Circle Amplification

(2009) Joonhyung Lee et al.   ANALYTICAL CHEMISTRY

Rolling Circle Amplification for Signal Enhancement in Ovalbumin Detection

(2009) Toshiro KOBORI et al.   ANALYTICAL SCIENCES

Full Dynamic Range Proteome Analysis of S. cerevisiae by Targeted Proteomics

(2009) Paola Picotti et al.   CELL

Bright-Field Microscopy Visualization of Proteins and Protein Complexes by In Situ Proximity Ligation with Peroxidase Detection

(2009) A. Zieba et al.   CLINICAL CHEMISTRY

MUC2 mucin is a major carrier of the cancer-associated sialyl-Tn antigen in intestinal metaplasia and gastric carcinomas

(2009) Tim Conze et al.   GLYCOBIOLOGY

Detection of gastric carcinoma-associated MG7-Ag by serum immuno-PCR assay in a high-risk Chinese population, with implication for screening

(2009) Lian Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

Gold nanoparticle enhanced immuno-PCR for ultrasensitive detection of Hantaan virus nucleocapsid protein

(2009) Longyan Chen et al.   JOURNAL OF IMMUNOLOGICAL METHODS

RAPID DETECTION OFBRUCELLA ABORTUSBY A NOVEL PROXIMITY LIGATION-BASED LOOP-MEDIATED ISOTHERMAL AMPLIFICATION METHOD

(2009) CHENGGANG ZHU et al.   JOURNAL OF RAPID METHODS AND AUTOMATION IN MICROBIOLOGY

Immunomagnetic quantitative immuno-PCR for detection of less than one HIV-1 virion

(2009) Janet Barletta et al.   JOURNAL OF VIROLOGICAL METHODS

Novel means of viral antigen identification: Improved detection of avian influenza viruses by proximity ligation

(2009) Joerg Schlingemann et al.   JOURNAL OF VIROLOGICAL METHODS

Sensitive Plasma Protein Analysis by Microparticle-based Proximity Ligation Assays

(2009) Spyros Darmanis et al.   MOLECULAR & CELLULAR PROTEOMICS

High Content Screening for Inhibitors of Protein Interactions and Post-translational Modifications in Primary Cells by Proximity Ligation

(2009) Karl-Johan Leuchowius et al.   MOLECULAR & CELLULAR PROTEOMICS

High sensitivity detection of the glial fibrillary acidic protein as indicator for TSE risk material in meat products using an immuno-PCR

(2009) Thorsten Kuczius et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

(2009) Terri A Addona et al.   NATURE BIOTECHNOLOGY

Nanoparticle-based bio-barcode assay redefines "undetectable" PSA and biochemical recurrence after radical prostatectomy

(2009) C. S. Thaxton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensitivity by combination: immuno-PCR and related technologies

(2008) Michael Adler et al.   ANALYST

Determination of anthracene by real-time immuno-polymerase chain reaction assay

(2008) Hui-Sheng Zhuang et al.   ANALYTICA CHIMICA ACTA

Real-time PCR detection of protein analytes with conformation-switching aptamers

(2008) Litao Yang et al.   ANALYTICAL BIOCHEMISTRY

Application of highly sensitive, modified glass substrate-based immuno-PCR on the early detection of nasopharyngeal carcinoma

(2008) Tzu-Wei Wang et al.   BIOMATERIALS

Multiplexed Proximity Ligation Assays to Profile Putative Plasma Biomarkers Relevant to Pancreatic and Ovarian Cancer

(2008) S. Fredriksson et al.   CLINICAL CHEMISTRY

BlobFinder, a tool for fluorescence microscopy image cytometry

(2008) A. Allalou et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

New Immuno-PCR Assay for Detection of Low Concentrations of Shiga Toxin 2 and Its Variants

(2008) W. Zhang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Determination of fluoranthene by antigen-coated indirect competitive real-time immuno-PCR assay

(2008) Chun Zhou et al.   JOURNAL OF ENVIRONMENTAL MONITORING

Detection of naphthalene by real-time immuno-PCR using molecular beacon

(2008) Qiyan Ye et al.   MOLECULAR AND CELLULAR PROBES

Detection of HIV-1 p24 Gag in plasma by a nanoparticle-based bio-barcode-amplification method

(2008) Eun-Young Kim et al.   Nanomedicine

Integrated barcode chips for rapid, multiplexed analysis of proteins in microliter quantities of blood

(2008) Rong Fan et al.   NATURE BIOTECHNOLOGY

HIT: a versatile proteomics platform for multianalyte phenotyping of cytokines, intracellular proteins and surface molecules

(2008) Michael G Kattah et al.   NATURE MEDICINE

A dual-tag microarray platform for high-performance nucleic acid and protein analyses

(2008) Olle Ericsson et al.   NUCLEIC ACIDS RESEARCH

A novel sensitive immunoassay method based on the Invader technique

(2007) Min-Jue Xie et al.   ANALYTICAL BIOCHEMISTRY

Assessment of the diagnostic potential of immuno-RCA in 96-well ELISA plates for foot-and-mouth disease virus

(2007) Wesley Van Dessel et al.   JOURNAL OF VIROLOGICAL METHODS