Brivaracetam for the treatment of epilepsy in adults

Brivaracetam as adjunctive treatment for uncontrolled partial epilepsy in adults: A phase III randomized, double-blind, placebo-controlled trial

(2013) Victor Biton et al.   EPILEPSIA

Adjunctive brivaracetam for uncontrolled focal and generalized epilepsies: Results of a phase III, double-blind, randomized, placebo-controlled, flexible-dose trial

(2013) Patrick Kwan et al.   EPILEPSIA

Adjunctive brivaracetam in adults with uncontrolled focal epilepsy: Results from a double-blind, randomized, placebo-controlled trial

(2013) Philippe Ryvlin et al.   EPILEPSIA

Investigating psychotropic properties of antiepileptic drugs

(2013) Marco Mula   Expert Review of Neurotherapeutics

Effect of brivaracetam (400 mg/day) on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive in healthy women

(2013) Armel Stockis et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Brivaracetam Disposition in Mild to Severe Hepatic Impairment

(2013) Armel Stockis et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Genetic variation in dopaminergic activity is associated with the risk for psychiatric side effects of levetiracetam

(2012) Christoph Helmstaedter et al.   EPILEPSIA

Efficacy and tolerability of adjunctive brivaracetam in adults with uncontrolled partial-onset seizures: A phase IIb, randomized, controlled trial

(2012) Wim Van Paesschen et al.   EPILEPSIA

Antiepileptic drug effects on mood and behavior: Molecular targets

(2012) Piero Perucca et al.   EPILEPSY & BEHAVIOR

Clinical efficacy and safety of the newer antiepileptic drugs as adjunctive treatment in adults with refractory partial-onset epilepsy: A meta-analysis of randomized placebo-controlled trials

(2012) Lan Gao et al.   EPILEPSY RESEARCH

Progress report on new antiepileptic drugs: A summary of the Eleventh Eilat Conference (EILAT XI)

(2012) Meir Bialer et al.   EPILEPSY RESEARCH

Brivaracetam Disposition in Renal Impairment

(2012) Maria Laura Sargentini-Maier et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: Relationship to anti-convulsant properties

(2011) Michel Gillard et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Progress report on new antiepileptic drugs: A summary of the Tenth Eilat Conference (EILAT X)

(2010) Meir Bialer et al.   EPILEPSY RESEARCH

Adjunctive brivaracetam for refractory partial-onset seizures: A randomized, controlled trial

(2010) J. A. French et al.   NEUROLOGY

Economic impact of epilepsy in the United States

(2009) Dokyoung Yoon et al.   EPILEPSIA

Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies

(2009) Patrick Kwan et al.   EPILEPSIA

Placebo-corrected efficacy of modern antiepileptic drugs for refractory epilepsy: Systematic review and meta-analysis

(2009) Stefan Beyenburg et al.   EPILEPSIA

Brivaracetam (ucb 34714) inhibits Na+ current in rat cortical neurons in culture

(2009) Cristina Zona et al.   EPILEPSY RESEARCH

Brivaracetam inhibits spreading depression in rat neocortical slices in vitro

(2009) Doru Georg Margineanu et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after multiple increasing oral doses in healthy men

(2008) Paul Rolan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Anti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A

(2008) A Matagne et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of brivaracetam on cardiac repolarisation – a thorough QT study

(2008) D. Rosillon et al.   CURRENT MEDICAL RESEARCH AND OPINION

The global burden and stigma of epilepsy

(2008) Hanneke M. de Boer et al.   EPILEPSY & BEHAVIOR

SV2A protein is a broad-spectrum anticonvulsant target: Functional correlation between protein binding and seizure protection in models of both partial and generalized epilepsy

(2007) Rafal M. Kaminski et al.   NEUROPHARMACOLOGY