Acetyl-L-carnitine: from a biological curiosity to a drug for the peripheral nervous system and beyond

Carnitine derivatives

(2012) Mariano Malaguarnera   CURRENT OPINION IN GASTROENTEROLOGY

HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity

(2012) Mitsumasa Kurita et al.   NATURE NEUROSCIENCE

Metabotropic glutamate receptors and the control of chronic pain

(2011) Santina Chiechio et al.   CURRENT OPINION IN PHARMACOLOGY

Growth Factors and Neuropathic Pain

(2011) Michael H. Ossipov   Current Pain and Headache Reports

Acetyl-L-Carnitine ameliorates spatial memory deficits induced by inhibition of phosphoinositol-3 kinase and protein kinase C

(2011) Xia Jiang et al.   JOURNAL OF NEUROCHEMISTRY

Advances in the diagnosis, pathogenesis and treatment of CIDP

(2011) Marinos C. Dalakas   Nature Reviews Neurology

Acetyl-l-Carnitine Attenuates Homocysteine-Induced Alzheimer-Like Histopathological and Behavioral Abnormalities

(2011) Peng Zhou et al.   REJUVENATION RESEARCH

Diagnostic and therapeutic challenges in chronic inflammatory demyelinating polyneuropathy and other immune-mediated neuropathies

(2010) Laurent Magy et al.   Current Opinion in Critical Care

Acetyl-l-carnitine increases artemin level and prevents neurotrophic factor alterations during neuropathy

(2010) E. Vivoli et al.   NEUROSCIENCE

Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain

(2010) Santina Chiechio et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection

(2009) V Valcour et al.   HIV MEDICINE

Ameliorating Hypertension and Insulin Resistance in Subjects at Increased Cardiovascular Risk

(2009) Piero Ruggenenti et al.   HYPERTENSION

Acetyl-l-carnitine increases nerve regeneration and target organ reinnervation – a morphological study

(2009) Andrew D.H. Wilson et al.   Journal of Plastic Reconstructive and Aesthetic Surgery

Epigenetic Modulation of mGlu2 Receptors by Histone Deacetylase Inhibitors in the Treatment of Inflammatory Pain

(2009) S. Chiechio et al.   MOLECULAR PHARMACOLOGY

Role of Acetyl-L-Carnitine in the Treatment of Diabetic Peripheral Neuropathy

(2008) Jeffery D Evans et al.   ANNALS OF PHARMACOTHERAPY

Group II metabotropic glutamate receptor activation on peripheral nociceptors modulates TRPV1 function

(2008) Susan M. Carlton et al.   BRAIN RESEARCH

Neuroprotective effects of acetyl-L-carnitine on neuropathic pain and apoptosis: A role for the nicotinic receptor

(2008) Lorenzo Di Cesare Mannelli et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Metabotropic Glutamate Receptors in Glial Cells

(2008) Simona D’Antoni et al.   NEUROCHEMICAL RESEARCH

Chemotherapy-evoked neuropathic pain: Abnormal spontaneous discharge in A-fiber and C-fiber primary afferent neurons and its suppression by acetyl-l-carnitine

(2007) Wen Hua Xiao et al.   PAIN