CNTF, STAT3 and new therapies for axonal degeneration: what are they and what can they do?

Axonal transcription factors signal retrogradely in lesioned peripheral nerve

(2012) Keren Ben-Yaakov et al.   EMBO JOURNAL

Local axonal function of STAT3 rescues axon degeneration in thepmnmodel of motoneuron disease

(2012) Bhuvaneish Thangaraj Selvaraj et al.   JOURNAL OF CELL BIOLOGY

The JAK/STAT Pathway Is Involved in Synaptic Plasticity

(2012) Céline S. Nicolas et al.   NEURON

γ-Secretase inhibitors and modulators for Alzheimer’s disease

(2011) Michael S. Wolfe   JOURNAL OF NEUROCHEMISTRY

Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model

(2011) Yimin Hua et al.   NATURE

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

(2011) Laura Ferraiuolo et al.   Nature Reviews Neurology

Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease

(2011) Eliezer Masliah et al.   PLoS One

GDP366, a novel small molecule dual inhibitor of survivin and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells

(2010) Xianping Shi et al.   CANCER BIOLOGY & THERAPY

STAT3-Stathmin Interactions Control Microtubule Dynamics in Migrating T-cells

(2009) Navin K. Verma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Function of Mitochondrial Stat3 in Cellular Respiration

(2009) J. Wegrzyn et al.   SCIENCE

Nmnat Delays Axonal Degeneration Caused by Mitochondrial and Oxidative Stress

(2008) C. Press et al.   JOURNAL OF NEUROSCIENCE