Anticancer therapies and CNS relapse: overcoming blood–brain and blood–cerebrospinal fluid barrier impermeability

Lapatinib Plus Capecitabine Resolved Human Epidermal Growth Factor Receptor 2-Positive Brain Metastases

(2009) Stefan Glück et al.   AMERICAN JOURNAL OF THERAPEUTICS

Intrathecal trastuzumab and thiotepa for leptomeningeal spread of breast cancer

(2009) C. Ferrario et al.   ANNALS OF ONCOLOGY

CNS events in elderly patients with aggressive lymphoma treated with modern chemotherapy (CHOP-14) with or without rituximab: an analysis of patients treated in the RICOVER-60 trial of the German High-Grade Non-Hodgkin Lymphoma Study Group (DSHNHL)

(2009) V. Boehme et al.   BLOOD

A phase III trial of topotecan and whole brain radiation therapy for patients with CNS-metastases due to lung cancer

(2009) T Neuhaus et al.   BRITISH JOURNAL OF CANCER

Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients

(2009) Y H Park et al.   BRITISH JOURNAL OF CANCER

Intracranial dural metastases

(2009) Lakshmi Nayak et al.   CANCER

Efficacy and safety of liposomal cytarabine in lymphoma patients with central nervous system involvement from lymphoma

(2009) Jose A. Garcia-Marco et al.   CANCER

Compartment-Specific Roles of ATP-Binding Cassette Transporters Define Differential Topotecan Distribution in Brain Parenchyma and Cerebrospinal Fluid

(2009) J. Shen et al.   CANCER RESEARCH

Multicenter Phase II Study of Lapatinib in Patients with Brain Metastases from HER2-Positive Breast Cancer

(2009) N. U. Lin et al.   CLINICAL CANCER RESEARCH

Convection-Enhanced Delivery: Neurosurgical Issues

(2009) W. Hall   CURRENT DRUG TARGETS

Diffuse large B-cell lymphoma with central nervous system relapse: prognosis and risk factors according to retrospective analysis from a single-center experience

(2009) Yutaka Shimazu et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Central Nervous System Metastases

(2009) Brian Leyland-Jones   JOURNAL OF CLINICAL ONCOLOGY

Phase I/II Trial of Tremelimumab in Patients With Metastatic Melanoma

(2009) Luis H. Camacho et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification of Leptomeningeal Disease in Aggressive B-Cell Non-Hodgkin's Lymphoma: Improved Sensitivity of Flow Cytometry

(2009) Sandra Quijano et al.   JOURNAL OF CLINICAL ONCOLOGY

High-dose intrathecal trastuzumab for leptomeningeal metastases secondary to HER-2 overexpressing breast cancer

(2008) O. Mir et al.   ANNALS OF ONCOLOGY

Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia

(2008) K. Porkka et al.   BLOOD

A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses

(2008) David Cameron et al.   BREAST CANCER RESEARCH AND TREATMENT

Effectiveness of intrathecal rituximab in patients with acute lymphoblastic leukaemia relapsed to the CNS and resistant to conventional therapy

(2008) José Carlos Jaime-Pérez et al.   BRITISH JOURNAL OF HAEMATOLOGY

Renal dysfunction during and after high-dose methotrexate

(2008) Myke R. Green et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

An Unexpected Synergist Role of P-Glycoprotein and Breast Cancer Resistance Protein on the Central Nervous System Penetration of the Tyrosine Kinase Inhibitor Lapatinib (N- -6-[5-( methyl)-2-furyl]-4-quinazolinamine; GW572016)

(2008) J. W. Polli et al.   DRUG METABOLISM AND DISPOSITION

First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX Plus125IUdR

(2008) C. Rebischung et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Natural History of CNS Relapse in Patients With Aggressive Non-Hodgkin's Lymphoma: A 20-Year Follow-Up Analysis of SWOG 8516—The Southwest Oncology Group

(2008) Steven H. Bernstein et al.   JOURNAL OF CLINICAL ONCOLOGY

Recurrent lymphomatous meningitis treated with intra-CSF rituximab and liposomal ara-C

(2008) Marc C. Chamberlain et al.   JOURNAL OF NEURO-ONCOLOGY

Prognostic factors and clinical outcomes in patients with leptomeningeal metastasis from solid tumors

(2008) Fusako Waki et al.   JOURNAL OF NEURO-ONCOLOGY

Strategies to advance translational research into brain barriers

(2008) Edward Neuwelt et al.   LANCET NEUROLOGY

A multicenter phase II trial of intrathecal topotecan in patients with meningeal malignancies

(2008) Morris D. Groves et al.   NEURO-ONCOLOGY

A pilot study: 131I-Antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost

(2008) David A. Reardon et al.   NEURO-ONCOLOGY