Article
Medicine, General & Internal
Masaharu Aga, Toru Naganuma, Yusuke Ohashi, Hiroki Matsuzawa, Suguru Matsuzaka, Ivor Cammack, Gen Yamada, Yoshimoto Serizawa
Summary: A retrospective cohort study found no reduction in in-hospital mortality with early antibiotic therapy for acute aspiration pneumonitis, but it was associated with longer hospital stays and prolonged antibiotic use in patients.
INTERNAL AND EMERGENCY MEDICINE
(2021)
Article
Infectious Diseases
Jonathan Binz, Mallory Heft, Samantha Robinson, Hanna Jensen, James Newton
Summary: This study investigates the use of procalcitonin (PCT) levels to differentiate between aspiration pneumonia (ASPNA) and aspiration pneumonitis. The results suggest that PCT levels differ significantly in these two conditions, and incorporating PCT levels into diagnostic criteria can lead to more appropriate treatment and improved antibiotic stewardship.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
(2023)
Article
Gastroenterology & Hepatology
Aoife M. Feighery, Nicholas R. Oblizajek, Matthew N. P. Vogt, Danse Bi, John League, Navtej S. Buttar, David O. Prichard
Summary: Residual food during esophagogastroduodenoscopy (EGD) is associated with an increased risk of gastric-to-pulmonary aspiration, especially when monitored anesthesia care (MAC) or general anesthesia (GA) are administered. The combination of residual food and MAC/GA is synergistically associated with increased odds of aspiration.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Review
Cardiac & Cardiovascular Systems
Jordi Almirall, Ramon Boixeda, Mari C. de la Torre, Antoni Torres
Summary: Aspiration pneumonia (AP) is a subtype of community-acquired pneumonia (CAP) that can be a potential cause of severe and life-threatening respiratory infection among frail and very old patients. While the diagnosis and prevention of AP can be difficult, establishing unified diagnostic criteria and prevention strategies is crucial.
RESPIRATORY MEDICINE
(2021)
Review
Physiology
Petra Kosutova, Pavol Mikolka
Summary: The passage discusses the impact of aspiration on pulmonary tissue, highlighting the potential health consequences of different types of aspiration syndromes and the clinical symptoms they may cause. It also outlines the detailed pathophysiological processes leading to lung tissue damage that can result from aspiration events.
PHYSIOLOGICAL RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Y. Zhang, K. Wang, H. Yu, T. Zhaoa, L. Lin, X. Qin, T. Wua, D. Chen, Y. Hua, Y. Wu
Summary: This study aimed to estimate the incidence and characteristics of aspiration pneumonia (AP) in Beijing, China. A historical cohort study was conducted using medical claim records. The results showed that the incidence of AP and pneumonia with risk factors for aspiration (PRFA) increased with age and patients with AP and PRFA had a higher burden of comorbidities compared to community-acquired pneumonia (CAP) patients. The 6-month and 1-year all-cause mortality rates were also higher for AP and PRFA patients compared to CAP patients. This study provides important baseline information for the prevention of AP.
Review
Geriatrics & Gerontology
Yuki Yoshimatsu, Yoichi Ohtake, Mamiko Ukai, Taiju Miyagami, Toru Morikawa, Yoshinosuke Shimamura, Yuki Kataoka, Tadayuki Hashimoto
Summary: This scoping review identified 12 clinical competencies required in the management of older adults with aspiration pneumonia. These competencies include diagnosis, treatment, swallow assessment, underlying condition management, nutrition, oral management, rehabilitation, multidisciplinary team, decision making, prevention, prognosis, and palliative care. Healthcare professionals are encouraged to share these competencies to improve patient care, with a focus on supportive care.
EUROPEAN GERIATRIC MEDICINE
(2023)
Review
Medicine, General & Internal
Aamer Imdad, Alice G. Wang, Vaishali Adlakha, Natalie M. Crespo, Jill Merrow, Abigail Smith, Olivia Tsistinas, Emily Tanner-Smith, Rachel Rosen
Summary: This study conducted a systematic review and meta-analysis to assess the risk of aspiration pneumonia in children with laryngeal penetration or tracheal aspiration. The results showed that laryngeal penetration may be associated with aspiration pneumonia, but the evidence was not conclusive. On the other hand, tracheal aspiration was found to be significantly associated with aspiration pneumonia. Further research with clear definitions and comprehensive measurements is needed to fully understand the association between laryngeal penetration and aspiration pneumonia.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, Research & Experimental
Yun-Xiao Bai, Jing-Jing Han, Jie Liu, Xia Li, Zhen-Zhen Xu, Yong Lv, Ke-Xuan Liu, Qing-Ping Wu
Summary: This study aimed to evaluate the efficacy of sugammadex on postoperative pulmonary complications (PPCs) in susceptible patients with ARISCAT-defined risk factors. The results showed that sugammadex significantly reduced the incidence of PPCs, residual neuromuscular block, atelectasis, pneumonia, and respiratory failure compared to neostigmine. Adverse events did not differ between the two groups.
ADVANCES IN THERAPY
(2023)
Article
Medicine, General & Internal
Dirk Bandorski, Khodr Tello, Harun Erdal, Janine Sommerlad, Jochen Wilhelm, Istvan Vadasz, Matthias Hecker, Dieter Walmrath, Werner Seeger, Ekaterina Krauss, Stefan Kuhnert
Summary: This study evaluates the diagnostic value of gastric biomarkers, such as pepsin and bile acid, in detecting aspiration in the intensive care unit (ICU). The results indicate that measuring pepsin and bile acid does not reliably diagnose aspiration or significantly impact survival outcomes. Further validation studies are needed to assess the clinical usefulness and reliability of these biomarkers in diagnosing aspiration-related conditions.
JOURNAL OF CLINICAL MEDICINE
(2023)
Letter
Otorhinolaryngology
Ru Tang, Jiayao Zhou, Shiyao Zhang, Song Mao, Weitian Zhang
Summary: This study evaluated the association between cerebrospinal fluid (CSF) leaks and aspiration pneumonitis (AP). The results showed that AP secondary to CSF leaks is frequently underestimated and neglected. Spontaneous CSF leaks are associated with a higher incidence of AP.
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Suzanne Suk Kwan Tso, Ellie Leister, Claire Rebecca Sharp, Jane Heller, Justine S. Gibson
Summary: This study describes the clinical course, culture and susceptibility profiles of dogs and cats mechanically ventilated for tick paralysis. The majority of these cases had concurrent evidence of aspiration pneumonia. Appropriate use of antimicrobials improved outcome. Clinicians should be aware of the development of bacterial pneumonia and select antimicrobials based on culture and susceptibility testing.
Article
Allergy
Silvia Sanchez-Diez, Xavier Munoz, Inigo Ojanguren, Christian Romero-Mesones, David Espejo, Ana Villar, Susana Gomez-Olles, Maria-Jesus Cruz
Summary: This study investigates the value of KL-6 and YKL-40 as biomarkers in the diagnosis and prognosis of patients with hypersensitivity pneumonitis (HP). The results suggest that KL-6 and YKL-40 have the potential to differentiate HP patients from healthy individuals and from those with idiopathic pulmonary fibrosis (IPF), with KL-6 possibly serving as a predictor of disease progression.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2022)
Article
Clinical Neurology
Bendix Labeit, Thalia Grond, Achim G. Beule, Maik Boehmer, Christian Thomas, Paul Muhle, Inga Claus, Malte Roderigo, Claudia Rudack, Heinz Wiendl, Rainer Dziewas, Tobias Warnecke, Sonja Suntrup-Krueger
Summary: The specific diagnostic algorithm presented in this study helps identify patients with an IIM-compatible dysphagia pattern and provides further IIM-focused diagnostic and therapeutic procedures. Treatment of patients diagnosed with IIM resulted in improvement of dysphagia in some cases post-therapy.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Multidisciplinary Sciences
Jun Hee Won, Seong Jun Byun, Byung-Mo Oh, Sang Jun Park, Han Gil Seo
Summary: Patients with Parkinson's disease are at an increased risk for aspiration pneumonia, with approximately two-thirds of patients dying within a year after experiencing it. Further studies are needed to prevent aspiration pneumonia and implement effective treatments to reduce mortality in PD patients.
SCIENTIFIC REPORTS
(2021)
