Recent progress in genetic variants associated with cancer and their implications in diagnostics development

Structural Variation in the Human Genome and its Role in Disease

(2010) Paweł Stankiewicz et al.   Annual Review of Medicine

Mature MicroRNA Sequence Polymorphism in MIR196A2 Is Associated with Risk and Prognosis of Head and Neck Cancer

(2010) B. C. Christensen et al.   CLINICAL CANCER RESEARCH

Micromarkers: miRNAs in cancer diagnosis and prognosis

(2010) Manuela Ferracin et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Conquering cancer through discovery research

(2010) William C. S. Cho   IUBMB LIFE

A Compendium of Genome-Wide Associations for Cancer: Critical Synopsis and Reappraisal

(2010) John P. A. Ioannidis et al.   JNCI-Journal of the National Cancer Institute

Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk

(2010) Dalemari Crowther-Swanepoel et al.   NATURE GENETICS

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

(2010) Gloria M Petersen et al.   NATURE GENETICS

A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci

(2010) Jin-Xin Bei et al.   NATURE GENETICS

Genome-wide association study identifies five new breast cancer susceptibility loci

(2010) Clare Turnbull et al.   NATURE GENETICS

Uncovering the roles of rare variants in common disease through whole-genome sequencing

(2010) Elizabeth T. Cirulli et al.   NATURE REVIEWS GENETICS

Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer

(2010) Antonella Galvan et al.   TRENDS IN GENETICS

Copy Number Variation in Human Health, Disease, and Evolution

(2009) Feng Zhang et al.   Annual Review of Genomics and Human Genetics

Genome-wide association studies of bladder cancer risk: a field synopsis of progress and potential applications

(2009) Xifeng Wu et al.   CANCER AND METASTASIS REVIEWS

Lung Adenocarcinoma with EGFR Amplification Has Distinct Clinicopathologic and Molecular Features in Never-Smokers

(2009) L. M. Sholl et al.   CANCER RESEARCH

Genetic variation of regulatory systems

(2009) Antigone S Dimas et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Role of miRNAs in lung cancer

(2009) William CS Cho   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

MicroRNAs: Potential biomarkers for cancer diagnosis, prognosis and targets for therapy

(2009) William C.S. Cho   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Genomic copy number variation, human health, and disease

(2009) Louise V Wain et al.   LANCET

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

New common variants affecting susceptibility to basal cell carcinoma

(2009) Simon N Stacey et al.   NATURE GENETICS

Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility

(2009) Margaret Wrensch et al.   NATURE GENETICS

Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

(2009) Julius Gudmundsson et al.   NATURE GENETICS

Common variations in BARD1 influence susceptibility to high-risk neuroblastoma

(2009) Mario Capasso et al.   NATURE GENETICS

Genome-wide association study identifies three loci associated with melanoma risk

(2009) D Timothy Bishop et al.   NATURE GENETICS

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

(2009) Elli Papaemmanuil et al.   NATURE GENETICS

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)

(2009) Gilles Thomas et al.   NATURE GENETICS

Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1

(2009) Wei Zheng et al.   NATURE GENETICS

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2

(2009) Shahana Ahmed et al.   NATURE GENETICS

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

(2009) Laufey Amundadottir et al.   NATURE GENETICS

Copy-number variation: the end of the human genome?

(2009) Paul H. Dear   TRENDS IN BIOTECHNOLOGY

Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas

(2008) X. Tang et al.   Cancer Prevention Research

Epidermal Growth Factor Receptor Gene Amplification Is Acquired in Association with Tumor Progression of EGFR-Mutated Lung Cancer

(2008) Y. Yatabe et al.   CANCER RESEARCH

A SNP in a let-7 microRNA Complementary Site in the KRAS 3' Untranslated Region Increases Non-Small Cell Lung Cancer Risk

(2008) L. J. Chin et al.   CANCER RESEARCH

A variant affecting a putative miRNA target site in estrogen receptor (ESR) 1 is associated with breast cancer risk in premenopausal women

(2008) Sandrine Tchatchou et al.   CARCINOGENESIS

The success of the genome-wide association approach: a brief story of a long struggle

(2008) Ku Chee Seng et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Sequential Molecular Changes during Multistage Pathogenesis of Small Peripheral Adenocarcinomas of the Lung

(2008) Junichi Soh et al.   Journal of Thoracic Oncology

Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits

(2008) Simon N Stacey et al.   NATURE GENETICS

Common 5p15.33 and 6p21.33 variants influence lung cancer risk

(2008) Yufei Wang et al.   NATURE GENETICS

Multiple loci identified in a genome-wide association study of prostate cancer

(2008) Gilles Thomas et al.   NATURE GENETICS

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21

(2008) Albert Tenesa et al.   NATURE GENETICS

Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer

(2008) Hiromi Sakamoto et al.   NATURE GENETICS

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS

A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia

(2008) Maria Chiara Di Bernardo et al.   NATURE GENETICS

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

(2008) Julius Gudmundsson et al.   NATURE GENETICS

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

(2008) Ian PM Tomlinson et al.   NATURE GENETICS

Lung cancer susceptibility locus at 5p15.33

(2008) James D McKay et al.   NATURE GENETICS

Common sequence variants on 20q11.22 confer melanoma susceptibility

(2008) Kevin M Brown et al.   NATURE GENETICS

Common variants on chromosome 5p12 confer susceptibility to estrogen receptor–positive breast cancer

(2008) Simon N Stacey et al.   NATURE GENETICS

Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome

(2008) A. Shlien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA target site polymorphisms and human disease

(2008) Praveen Sethupathy et al.   TRENDS IN GENETICS