Advances and perspectives from genetic research: development of biological markers in Alzheimer’s disease

Creativity in the Context of Neurologic Illness

(2016) Bruce L. Miller   CNS SPECTRUMS

APOE ε4 Genotype and Longitudinal Changes in Cerebral Blood Flow in Normal Aging

(2010) Madhav Thambisetty et al.   ARCHIVES OF NEUROLOGY

High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation

(2010) David O Azorsa et al.   BMC GENOMICS

Apolipoprotein E4allele in the normal elderly: neuropsychologic and brain MRI correlates

(2010) H. Schmidt et al.   CLINICAL GENETICS

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects

(2010) Kristel Sleegers et al.   TRENDS IN GENETICS

Genetics of Alzheimer disease in the pre- and post-GWAS era

(2010) Nilüfer Ertekin-Taner   Alzheimers Research & Therapy

Amyloid precursor protein transgenic mouse models and Alzheimer's disease: Understanding the paradigms, limitations, and contributions

(2009) Tyler A. Kokjohn et al.   Alzheimers & Dementia

Serotonergic System Genes in Psychosis of Alzheimer Dementia: Meta-Analysis

(2009) Seethalakshmi Ramanathan et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Genome-wide Association Study Implicates a Chromosome 12 Risk Locus for Late-Onset Alzheimer Disease

(2009) Gary W. Beecham et al.   AMERICAN JOURNAL OF HUMAN GENETICS

APOEpredicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

(2009) John C. Morris et al.   ANNALS OF NEUROLOGY

CSF Biomarkers

(2009) Niklas Mattsson et al.   Annals of the New York Academy of Sciences

Use of Genetic Variation as Biomarkers for Alzheimer's Disease

(2009) Christiane Reitz et al.   Annals of the New York Academy of Sciences

APOE-4 Genotype and Neurophysiological Vulnerability to Alzheimer's and Cognitive Aging

(2009) Susan Bookheimer et al.   Annual Review of Clinical Psychology

Influence of Cognitive Status, Age, and APOE-4 Genetic Risk on Brain FDDNP Positron-Emission Tomography Imaging in Persons Without Dementia

(2009) Gary W. Small et al.   ARCHIVES OF GENERAL PSYCHIATRY

A Genomewide Association Study Points to Multiple Loci That Predict Antidepressant Drug Treatment Outcome in Depression

(2009) Marcus Ising et al.   ARCHIVES OF GENERAL PSYCHIATRY

The GAB2 Gene and the Risk of Alzheimer's Disease: Replication and Meta-Analysis

(2009) M. Arfan Ikram et al.   BIOLOGICAL PSYCHIATRY

Cortical Binding of Pittsburgh Compound B, an Endophenotype for Genetic Studies of Alzheimer's Disease

(2009) Anthony L. Hinrichs et al.   BIOLOGICAL PSYCHIATRY

MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers

(2009) N. Schuff et al.   BRAIN

Association of SORL1 gene variants with Alzheimer's disease

(2009) Heike Kölsch et al.   BRAIN RESEARCH

Clusterin: A forgotten player in Alzheimer's disease

(2009) Tapio Nuutinen et al.   BRAIN RESEARCH REVIEWS

Biological Marker Candidates of Alzheimer's Disease in Blood, Plasma, and Serum

(2009) Philine Schneider et al.   CNS Neuroscience & Therapeutics

The Role of Vascular Factors in Late-Onset Sporadic Alzheimers Disease. Genetic and Molecular Aspects

(2009) A. Rocchi et al.   Current Alzheimer Research

Epigenetic dysregulation in cognitive disorders

(2009) Johannes Gräff et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Epigenetics, oxidative stress, and Alzheimer disease

(2009) Nasser H. Zawia et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genome-wide association studies in Alzheimer's disease

(2009) L. Bertram et al.   HUMAN MOLECULAR GENETICS

Investigation of dopamine receptors in susceptibility to behavioural and psychological symptoms in Alzheimer's disease

(2009) Antonia L. Pritchard et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Elderly Patients With Dementia-Related Symptoms of Severe Agitation and Aggression

(2009) Carl Salzman et al.   JOURNAL OF CLINICAL PSYCHIATRY

Examination of the current top candidate genes for AD in a genome-wide association study

(2009) T M Feulner et al.   MOLECULAR PSYCHIATRY

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

(2009) Minerva M Carrasquillo et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Meta-analysis of linkage studies for Alzheimer's disease—A web resource

(2009) Amy W. Butler et al.   NEUROBIOLOGY OF AGING

Sequence variation in SORL1 and dementia risk in Swedes

(2009) Chandra A. Reynolds et al.   NEUROGENETICS

Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease

(2009) A. Drzezga et al.   NEUROLOGY

The Role of Apolipoprotein E in Alzheimer's Disease

(2009) Jungsu Kim et al.   NEURON

Fibrillar amyloid-  burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

(2009) E. M. Reiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics of Alzheimer's disease: recent advances

(2009) Dimitrios Avramopoulos   Genome Medicine

Hippocampal volumes are important predictors for memory function in elderly women

(2009) Martin A Ystad et al.   BMC MEDICAL IMAGING

Disease-modifying therapies in Alzheimer’s disease

(2008) Stephen Salloway et al.   Alzheimers & Dementia

Apolipoprotein E represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer’s disease

(2008) Judes Poirier   Alzheimers & Dementia

Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE

(2008) Lars Bertram et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis

(2008) S.E. Poduslo et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

(2008) Richard Abraham et al.   BMC Medical Genomics

Increased CSF-BACE 1 activity is associated with ApoE-ε4 genotype in subjects with mild cognitive impairment and Alzheimer's disease

(2008) Michael Ewers et al.   BRAIN

Neuropsychological performance in advanced age: Influences of Demographic factors and Apolipoprotein E: Findings from the Cache County Memory Study

(2008) Katheen A. Welsh-Bohmer et al.   CLINICAL NEUROPSYCHOLOGIST

Pharmacogenomics and therapeutic prospects in dementia

(2008) Ramón Cacabelos   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

GAB2 is not associated with late-onset Alzheimer's disease in Japanese

(2008) Akinori Miyashita et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Novel MRI techniques in the assessment of dementia

(2008) Stefan J. Teipel et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Amyloid plaque imaging in vivo: current achievement and future prospects

(2008) Agneta Nordberg   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Vascular risk factors and Alzheimer’s disease

(2008) David F Cechetto et al.   Expert Review of Neurotherapeutics

SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population

(2008) Karolien Bettens et al.   HUMAN MUTATION

Common variation inGRB-associated Binding Protein 2 (GAB2)and increased risk for Alzheimer dementia

(2008) Kristel Sleegers et al.   HUMAN MUTATION

Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD

(2008) J. Wu et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's disease: advances in trafficking

(2008) Richard Mayeux et al.   LANCET NEUROLOGY

Therapeutic Strategies for Alzheimer’s Disease

(2008) Donna M. Barten et al.   MOLECULAR NEUROBIOLOGY

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

(2008) Lars Bertram et al.   NATURE REVIEWS NEUROSCIENCE

Association study of the GAB2 gene with the risk of developing Alzheimer's disease

(2008) Julien Chapuis et al.   NEUROBIOLOGY OF DISEASE

Alzheimer’s disease risk variants show association with cerebrospinal fluid amyloid beta

(2008) John S. K. Kauwe et al.   NEUROGENETICS

APOE  4 allele predicts faster cognitive decline in mild Alzheimer disease

(2008) S. Cosentino et al.   NEUROLOGY

Amyloid imaging in Alzheimer's disease

(2008) Agneta Nordberg   NEUROPSYCHOLOGIA

The Medical and Economic Roles of Pipeline Pharmacogenetics: Alzheimer's Disease as a Model of Efficacy and HLA-B*5701 as a Model of Safety

(2008) Allen D Roses   NEUROPSYCHOPHARMACOLOGY

No association of SORL1 SNPs with Alzheimer's disease

(2008) Ryan L. Minster et al.   NEUROSCIENCE LETTERS

Influence of SORL1 gene variants: Association with CSF amyloid-β products in probable Alzheimer's disease

(2008) Heike Kölsch et al.   NEUROSCIENCE LETTERS

Pharmacogenomics and treatment for dementia induced by Alzheimer’s disease

(2008) Meenal Gupta et al.   PHARMACOGENOMICS

Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease

(2008) Sun-Chong Wang et al.   PLoS One

Core candidate neurochemical and imaging biomarkers of Alzheimer’s disease

(2007) Harald Hampel et al.   Alzheimers & Dementia

Candidate Single-Nucleotide Polymorphisms From a Genomewide Association Study of Alzheimer Disease

(2007) Hao Li et al.   ARCHIVES OF NEUROLOGY

Hypometabolism and Altered Cerebrospinal Fluid Markers in Normal Apolipoprotein E E4 Carriers with Subjective Memory Complaints

(2007) Lisa Mosconi et al.   BIOLOGICAL PSYCHIATRY

The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease

(2007) Lidia Glodzik-Sobanska et al.   NEUROBIOLOGY OF AGING

SORL1 variants and risk of late-onset Alzheimer’s disease

(2007) Yonghong Li et al.   NEUROBIOLOGY OF DISEASE

Role of 5HT2A and 5HT2C polymorphisms in behavioural and psychological symptoms of Alzheimer's disease

(2006) Antonia L. Pritchard et al.   NEUROBIOLOGY OF AGING