Mea Culpawith cancer-targeted therapy: new thinking and new agents design for novel, causal networks-based, personalized biomedicine

Trial Offers Early Test Case for Personalized Medicine

(2009) K. Garber   JNCI-Journal of the National Cancer Institute

HER2 and Trastuzumab: Impact of a New Standard Agent on Local Control and Surgery for Breast Cancer

(2008) Dimosthenis Ziogas et al.   ANNALS OF SURGICAL ONCOLOGY

Human Genetic and Structural Genomic Variation: Would Genome-Wide Association Studies Be the Solution for Cancer Complexity Like Alexander the Great for the “Gordian Knot”?

(2008) Dimitrios H. Roukos et al.   ANNALS OF SURGICAL ONCOLOGY

Personal Genomics and Genome-Wide Association Studies: Novel Discoveries but Limitations for Practical Personalized Medicine

(2008) Dimitrios H. Roukos   ANNALS OF SURGICAL ONCOLOGY

THE LOCI OF EVOLUTION: HOW PREDICTABLE IS GENETIC EVOLUTION?

(2008) David L. Stern et al.   EVOLUTION

Genetics and genome-wide association studies: surgery-guided algorithm and promise for future breast cancer personalized surgery

(2008) Dimitrios H Roukos   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Assessing both genetic variation (SNPs/CNVs) and gene–environment interactions may lead to personalized gastric cancer prevention

(2008) Dimitrios H Roukos   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Genome-wide association studies in cancer

(2008) D. F. Easton et al.   HUMAN MOLECULAR GENETICS

Current and Future Utilization of Services From Medical Oncologists

(2008) Joan L. Warren et al.   JOURNAL OF CLINICAL ONCOLOGY

Wild-TypeBRAFIs Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer

(2008) Federica Di Nicolantonio et al.   JOURNAL OF CLINICAL ONCOLOGY

Quo Vadis With Targeted Drugs in the 21st Century?

(2008) Jonas Bergh   JOURNAL OF CLINICAL ONCOLOGY

Cancer: The Road to Amiens

(2008) David J. Stewart et al.   JOURNAL OF CLINICAL ONCOLOGY

Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer

(2008) Helena Linardou et al.   LANCET ONCOLOGY

Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial

(2008)   LANCET ONCOLOGY

Quantitative genetics

(2008) Chris Gunter   NATURE

Reverse engineering the genotype–phenotype map with natural genetic variation

(2008) Matthew V. Rockman   NATURE

Progress and challenges in genome-wide association studies in humans

(2008) Peter Donnelly   NATURE

Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

(2008) Jun Zhu et al.   NATURE GENETICS

HER2 and Response to Paclitaxel in Node-Positive Breast Cancer

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Targeting EGFR in Colorectal Cancer

(2008) Wells A. Messersmith et al.   NEW ENGLAND JOURNAL OF MEDICINE

EGFR Antagonists in Cancer Treatment

(2008) Fortunato Ciardiello et al.   NEW ENGLAND JOURNAL OF MEDICINE

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE

Linking contralateral breast cancer with genetics

(2008) Dimitrios H. Roukos   RADIOTHERAPY AND ONCOLOGY

From Signals to Patterns: Space, Time, and Mathematics in Developmental Biology

(2008) J. Lewis   SCIENCE

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

In silico cancer modeling: is it ready for prime time?

(2008) Thomas S Deisboeck et al.   Nature clinical practice. Oncology

Gene–Environment Interaction in Yeast Gene Expression

(2008) Erin N Smith et al.   PLOS BIOLOGY